Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004843 | molecular_function | cysteine-type deubiquitinase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0006508 | biological_process | proteolysis |
| A | 0008234 | molecular_function | cysteine-type peptidase activity |
| A | 0016579 | biological_process | protein deubiquitination |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0035871 | biological_process | protein K11-linked deubiquitination |
| A | 0043130 | molecular_function | ubiquitin binding |
| A | 0070536 | biological_process | protein K63-linked deubiquitination |
| A | 0071108 | biological_process | protein K48-linked deubiquitination |
| A | 2000780 | biological_process | negative regulation of double-strand break repair |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | binding site for residue J51 A 301 |
| Chain | Residue |
| A | GLY47 |
| A | ASP48 |
| A | ARG49 |
| A | ASN50 |
| A | CYS51 |
| A | THR222 |
| A | SER223 |
| A | HOH521 |
| A | HOH552 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 302 |
| Chain | Residue |
| A | ARG38 |
| A | GLN192 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 303 |
| Chain | Residue |
| A | PHE6 |
| A | ASN7 |
| A | LEU8 |
| A | LYS44 |
| A | LYS46 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue PEG A 304 |
| Chain | Residue |
| A | ASP129 |
| A | HIS130 |
| A | MET171 |
| A | HOH403 |
| A | HOH404 |
| A | HOH484 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 305 |
| Chain | Residue |
| A | GLY89 |
| A | ARG144 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 306 |
| Chain | Residue |
| A | ALA202 |
| A | ASN204 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 307 |
| Chain | Residue |
| A | ASP176 |
| A | HIS177 |
| A | ILE180 |
| A | TYR195 |
| A | TYR225 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP48 | |
| A | HIS224 | |
| Chain | Residue | Details |
| A | CYS51 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | SITE: Required to orient and stabilize the active site H-224 => ECO:0000305|PubMed:15258613 |
| Chain | Residue | Details |
| A | ASN226 | |
