Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006508 | biological_process | proteolysis |
| A | 0008234 | molecular_function | cysteine-type peptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008234 | molecular_function | cysteine-type peptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | binding site for residue BGJ A 901 |
| Chain | Residue |
| A | GLY23 |
| A | VAL162 |
| A | ASN163 |
| A | HIS164 |
| A | GLY165 |
| A | SO4902 |
| A | HOH1107 |
| A | HOH1117 |
| B | GLU115 |
| B | TYR118 |
| B | HOH1046 |
| A | GLY62 |
| A | CYS66 |
| A | ASN67 |
| A | GLY68 |
| A | GLY69 |
| A | PHE70 |
| A | MET71 |
| A | ASN161 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 A 902 |
| Chain | Residue |
| A | GLN19 |
| A | GLY23 |
| A | ALA24 |
| A | SER25 |
| A | ASN163 |
| A | HIS164 |
| A | TRP186 |
| A | BGJ901 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 903 |
| Chain | Residue |
| A | LYS177 |
| A | HOH1050 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 904 |
| Chain | Residue |
| A | LYS125 |
| A | GLU178 |
| A | ARG200 |
| A | ASN201 |
| A | HOH1024 |
| A | HOH1090 |
| site_id | AC5 |
| Number of Residues | 12 |
| Details | binding site for residue BGJ B 901 |
| Chain | Residue |
| A | GLU115 |
| A | TYR118 |
| A | HOH1136 |
| B | PHE70 |
| B | MET71 |
| B | ASN161 |
| B | VAL162 |
| B | HIS164 |
| B | GLY165 |
| B | PHE211 |
| B | HOH1046 |
| B | HOH1087 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 B 902 |
| Chain | Residue |
| B | GLN19 |
| B | GLY23 |
| B | ALA24 |
| B | SER25 |
| B | ASN163 |
| B | HIS164 |
| B | TRP186 |
Functional Information from PROSITE/UniProt
| site_id | PS00639 |
| Number of Residues | 11 |
| Details | THIOL_PROTEASE_HIS Eukaryotic thiol (cysteine) proteases histidine active site. VNHGVLVVGYG |
| Chain | Residue | Details |
| A | VAL162-GLY172 | |
| site_id | PS00640 |
| Number of Residues | 20 |
| Details | THIOL_PROTEASE_ASN Eukaryotic thiol (cysteine) proteases asparagine active site. YWLvKNSWghnFGeeGYIrM |
| Chain | Residue | Details |
| A | TYR179-MET198 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | ACT_SITE: ACT_SITE => ECO:0000250 |
| Chain | Residue | Details |
| A | SER25 | |
| A | HIS164 | |
| A | ASN184 | |
| B | SER25 | |
| B | HIS164 | |
| B | ASN184 | |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 4 |
| Details | M-CSA 814 |
| Chain | Residue | Details |
| A | GLN19 | electrostatic stabiliser |
| A | SER25 | nucleofuge, nucleophile, proton acceptor, proton donor |
| A | HIS164 | proton acceptor, proton donor |
| A | ASN184 | electrostatic stabiliser |
| site_id | MCSA2 |
| Number of Residues | 4 |
| Details | M-CSA 814 |
| Chain | Residue | Details |
| B | GLN19 | electrostatic stabiliser |
| B | SER25 | nucleofuge, nucleophile, proton acceptor, proton donor |
| B | HIS164 | proton acceptor, proton donor |
| B | ASN184 | electrostatic stabiliser |
