Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue ACT A 401 |
| Chain | Residue |
| A | CYS255 |
| A | ASP279 |
| A | GLY281 |
| A | CYS290 |
| A | HOH501 |
| A | HOH504 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ACT A 402 |
| Chain | Residue |
| A | HOH745 |
| A | SER154 |
| A | SER284 |
| A | THR285 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue ACT A 403 |
| Chain | Residue |
| A | ASP160 |
| A | GLY162 |
| A | PRO166 |
| A | GLY167 |
| A | LYS330 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue ACT A 404 |
| Chain | Residue |
| A | ALA298 |
| A | HOH661 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue DMS A 405 |
| Chain | Residue |
| A | ASP81 |
| A | GLY82 |
| A | SER83 |
| A | SER113 |
| A | SER114 |
| A | SER115 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue DMS A 406 |
| Chain | Residue |
| A | THR132 |
| A | LEU133 |
| A | LYS191 |
| site_id | AC7 |
| Number of Residues | 11 |
| Details | binding site for residue DD7 A 407 |
| Chain | Residue |
| A | ASP15 |
| A | ALA16 |
| A | GLY80 |
| A | ASP81 |
| A | GLY221 |
| A | THR222 |
| A | THR223 |
| A | ILE300 |
| A | ILE304 |
| A | HOH511 |
| A | HOH581 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue PEG A 408 |
| Chain | Residue |
| A | ALA187 |
| A | SER189 |
| A | GLU196 |
| A | THR198 |
| A | ASP215 |
| A | HOH645 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. LDFDTGSSDLWV |
| Chain | Residue | Details |
| A | LEU32-VAL43 | |
| A | GLY216-LEU227 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: |
| Chain | Residue | Details |
| A | ASP35 | |
| A | SER199 | |
