Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 401 |
| Chain | Residue |
| A | VAL272 |
| A | TYR277 |
| A | ALA312 |
| A | SER329 |
| A | LYS330 |
| A | HOH675 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 402 |
| Chain | Residue |
| A | THR8 |
| A | HOH508 |
| A | HOH658 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 403 |
| Chain | Residue |
| A | ALA203 |
| A | VAL204 |
| A | GLY207 |
| A | THR208 |
| A | LYS210 |
| A | HOH502 |
| A | HOH504 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 404 |
| Chain | Residue |
| A | ALA187 |
| A | SER189 |
| A | GLU196 |
| A | TRP197 |
| A | THR198 |
| A | ASP215 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 405 |
| Chain | Residue |
| A | LEU69 |
| A | GLY72 |
| A | GLY181 |
| A | SER182 |
| A | HOH540 |
| A | HOH665 |
| site_id | AC6 |
| Number of Residues | 11 |
| Details | binding site for residue GOL A 406 |
| Chain | Residue |
| A | SER182 |
| A | THR184 |
| A | VAL266 |
| A | ALA269 |
| A | ARG270 |
| A | ILE271 |
| A | PHE327 |
| A | ALA328 |
| A | SER329 |
| A | HOH503 |
| A | HOH540 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue DMS A 407 |
| Chain | Residue |
| A | GLY37 |
| A | SER78 |
| A | D6V409 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue DMS A 408 |
| Chain | Residue |
| A | SER4 |
| A | THR6 |
| A | HOH523 |
| site_id | AC9 |
| Number of Residues | 11 |
| Details | binding site for residue D6V A 409 |
| Chain | Residue |
| A | GLY37 |
| A | GLY80 |
| A | PHE194 |
| A | ASP219 |
| A | THR222 |
| A | ILE300 |
| A | ILE304 |
| A | DMS407 |
| A | HOH555 |
| A | HOH670 |
| A | HOH734 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue ACT A 411 |
| Chain | Residue |
| A | ASP279 |
| A | GLY281 |
| A | CYS290 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. LDFDTGSSDLWV |
| Chain | Residue | Details |
| A | LEU32-VAL43 | |
| A | GLY216-LEU227 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 311 |
| Details | Domain: {"description":"Peptidase A1","evidences":[{"source":"PROSITE-ProRule","id":"PRU01103","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {} |
