5QAU

OXA-48 IN COMPLEX WITH COMPOUND 26a

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008658	molecular_function	penicillin binding
A	0008800	molecular_function	beta-lactamase activity
A	0016787	molecular_function	hydrolase activity
A	0017001	biological_process	antibiotic catabolic process
A	0046677	biological_process	response to antibiotic
A	0046872	molecular_function	metal ion binding
B	0008658	molecular_function	penicillin binding
B	0008800	molecular_function	beta-lactamase activity
B	0016787	molecular_function	hydrolase activity
B	0017001	biological_process	antibiotic catabolic process
B	0046677	biological_process	response to antibiotic
B	0046872	molecular_function	metal ion binding
C	0008658	molecular_function	penicillin binding
C	0008800	molecular_function	beta-lactamase activity
C	0016787	molecular_function	hydrolase activity
C	0017001	biological_process	antibiotic catabolic process
C	0046677	biological_process	response to antibiotic
C	0046872	molecular_function	metal ion binding
D	0008658	molecular_function	penicillin binding
D	0008800	molecular_function	beta-lactamase activity
D	0016787	molecular_function	hydrolase activity
D	0017001	biological_process	antibiotic catabolic process
D	0046677	biological_process	response to antibiotic
D	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	binding site for residue CL A 301

Chain	Residue
A	ARG206
C	ARG206

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site_id	AC2
Number of Residues	5
Details	binding site for residue EDO A 302

Chain	Residue
A	LYS94
A	TRP95
A	ASP96
A	HOH452
A	HOH462

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site_id	AC3
Number of Residues	7
Details	binding site for residue EDO A 303

Chain	Residue
A	HOH426
A	HOH428
A	HOH522
C	ASP88
C	HIS90
A	HIS178
A	ASN179

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site_id	AC4
Number of Residues	5
Details	binding site for residue EDO A 304

Chain	Residue
A	GLN64
A	ALA65
A	PRO217
A	HOH483
A	HOH554

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site_id	AC5
Number of Residues	5
Details	binding site for residue EDO B 301

Chain	Residue
A	ARG214
B	ARG100
B	HOH416
B	HOH471
B	HOH549

---

site_id	AC6
Number of Residues	4
Details	binding site for residue EDO B 302

Chain	Residue
B	ASN110
B	HOH403
B	HOH526
B	HOH538

---

site_id	AC7
Number of Residues	7
Details	binding site for residue V7V C 301

Chain	Residue
C	SER70
C	SER118
C	THR209
C	GLY210
C	TYR211
C	ARG250
C	HOH401

---

site_id	AC8
Number of Residues	7
Details	binding site for residue EDO C 302

Chain	Residue
A	HIS90
A	HOH412
C	TYR177
C	GLU227
C	VAL232
C	HOH423
C	HOH482

---

site_id	AC9
Number of Residues	4
Details	binding site for residue EDO C 303

Chain	Residue
B	LYS60
B	GLN64
C	ASN146
C	GLU147

---

site_id	AD1
Number of Residues	9
Details	binding site for residue V7V D 301

Chain	Residue
D	SER70
D	SER118
D	THR209
D	GLY210
D	TYR211
D	SER244
D	LEU247
D	ARG250
D	HOH401

---

site_id	AD2
Number of Residues	1
Details	binding site for residue CL D 302

Chain	Residue
D	ARG206

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site_id	AD3
Number of Residues	4
Details	binding site for residue EDO D 303

Chain	Residue
D	LYS94
D	TRP95
D	ASP96
D	HOH432

---

site_id	AD4
Number of Residues	9
Details	binding site for residue EDO D 304

Chain	Residue
D	MET115
D	ALA194
D	MET195
D	LEU196
D	THR197
D	ALA207
D	LYS208
D	HOH415
D	HOH425

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Functional Information from PROSITE/UniProt

site_id	PS00337
Number of Residues	11
Details	BETA_LACTAMASE_D Beta-lactamase class-D active site. PaSTFKIPnSL

Chain	Residue	Details
A	PRO68-LEU78

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