Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003723 | molecular_function | RNA binding |
| A | 0003968 | molecular_function | RNA-dependent RNA polymerase activity |
| A | 0039694 | biological_process | viral RNA genome replication |
| B | 0003723 | molecular_function | RNA binding |
| B | 0003968 | molecular_function | RNA-dependent RNA polymerase activity |
| B | 0039694 | biological_process | viral RNA genome replication |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue 23E A 601 |
| Chain | Residue |
| A | ALA396 |
| A | HOH820 |
| B | 23E601 |
| B | HOH801 |
| B | HOH842 |
| A | HIS428 |
| A | LEU492 |
| A | GLY493 |
| A | VAL494 |
| A | PRO495 |
| A | ARG498 |
| A | VAL499 |
| A | ARG503 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | binding site for residue 2N5 A 602 |
| Chain | Residue |
| A | ARG200 |
| A | LEU204 |
| A | LEU314 |
| A | CYS316 |
| A | ASP319 |
| A | VAL321 |
| A | LEU360 |
| A | ILE363 |
| A | SER365 |
| A | CYS366 |
| A | SER368 |
| A | LEU384 |
| A | MET414 |
| A | TYR415 |
| A | TYR448 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 603 |
| Chain | Residue |
| A | HIS374 |
| A | ARG380 |
| A | GLY516 |
| A | ARG517 |
| A | HOH849 |
| A | HOH862 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 604 |
| Chain | Residue |
| A | THR329 |
| A | ARG505 |
| A | VAL530 |
| A | ARG531 |
| A | THR532 |
| A | HOH707 |
| A | HOH792 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 605 |
| Chain | Residue |
| A | ARG48 |
| A | LYS51 |
| A | ARG222 |
| A | CYS223 |
| A | HOH794 |
| A | HOH845 |
| A | HOH856 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 606 |
| Chain | Residue |
| A | SER84 |
| A | VAL85 |
| A | ARG120 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 607 |
| Chain | Residue |
| A | GLY188 |
| A | SER189 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 608 |
| Chain | Residue |
| A | ASP244 |
| A | LEU245 |
| A | PRO247 |
| A | GOL610 |
| A | HOH775 |
| A | HOH836 |
| B | ASN231 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 609 |
| Chain | Residue |
| A | ARG65 |
| A | ASN231 |
| A | VAL235 |
| A | HOH808 |
| B | LYS79 |
| B | ASP244 |
| B | GOL610 |
| site_id | AD1 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 610 |
| Chain | Residue |
| A | LYS79 |
| A | ASP244 |
| A | GOL608 |
| B | ARG65 |
| B | LEU68 |
| B | ASN231 |
| B | VAL235 |
| B | HOH852 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue PG4 A 611 |
| Chain | Residue |
| A | LYS209 |
| A | GLU361 |
| A | TYR382 |
| A | GLU437 |
| site_id | AD3 |
| Number of Residues | 13 |
| Details | binding site for residue 23E B 601 |
| Chain | Residue |
| A | ALA400 |
| A | ARG401 |
| A | 23E601 |
| B | ALA396 |
| B | HIS428 |
| B | LEU492 |
| B | GLY493 |
| B | VAL494 |
| B | PRO495 |
| B | ARG498 |
| B | VAL499 |
| B | ARG503 |
| B | HOH842 |
| site_id | AD4 |
| Number of Residues | 16 |
| Details | binding site for residue 2N5 B 602 |
| Chain | Residue |
| B | LEU360 |
| B | ILE363 |
| B | SER365 |
| B | CYS366 |
| B | SER368 |
| B | LEU384 |
| B | MET414 |
| B | TYR415 |
| B | TYR448 |
| B | PRO197 |
| B | ARG200 |
| B | LEU204 |
| B | LEU314 |
| B | CYS316 |
| B | ASP319 |
| B | VAL321 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 603 |
| Chain | Residue |
| B | ARG48 |
| B | LYS51 |
| B | ARG222 |
| B | CYS223 |
| site_id | AD6 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 B 604 |
| Chain | Residue |
| B | GLU361 |
| B | SER478 |
| B | PRO479 |
| B | GLY480 |
| B | GLU481 |
| B | HOH722 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 605 |
| Chain | Residue |
| B | ARG505 |
| B | VAL530 |
| B | ARG531 |
| B | THR532 |
| site_id | AD8 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 606 |
| Chain | Residue |
| B | HIS475 |
| B | SER476 |
| B | HOH847 |
| site_id | AD9 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 B 607 |
| Chain | Residue |
| B | GLY188 |
| B | SER189 |
| site_id | AE1 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 608 |
| Chain | Residue |
| B | GLY516 |
| B | ARG517 |
| B | HOH881 |
| site_id | AE2 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 609 |
| Chain | Residue |
| B | SER84 |
| B | VAL85 |
| B | GLU86 |
| B | ARG120 |
| site_id | AE3 |
| Number of Residues | 7 |
| Details | binding site for residue GOL B 610 |
| Chain | Residue |
| A | ASN231 |
| A | GOL609 |
| B | ASP244 |
| B | LEU245 |
| B | PRO247 |
| B | HOH729 |
| B | HOH794 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP220 | |
| A | ASP318 | |
| A | ASP319 | |
| B | ASP220 | |
| B | ASP318 | |
| B | ASP319 | |
| Chain | Residue | Details |
| A | SER29 | |
| A | SER42 | |
| B | SER29 | |
| B | SER42 | |
