Functional Information from GO Data
| Chain | GOid | namespace | contents |
| C | 0004252 | molecular_function | serine-type endopeptidase activity |
| C | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 301 |
| Chain | Residue |
| A | SER163 |
| A | ASP164 |
| A | HOH405 |
| C | ARG331 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 302 |
| Chain | Residue |
| A | HOH402 |
| A | HOH439 |
| C | SER453 |
| C | GLU454 |
| C | HOH712 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 303 |
| Chain | Residue |
| A | ARG173 |
| A | CYS174 |
| A | TYR178 |
| A | SER179 |
| A | LEU180 |
| A | HOH402 |
| A | HOH415 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue CA C 501 |
| Chain | Residue |
| C | GLU270 |
| C | ASP272 |
| C | GLU275 |
| C | GLU280 |
| C | HOH645 |
| C | HOH782 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 C 502 |
| Chain | Residue |
| C | MET366 |
| C | THR367 |
| C | ARG439 |
| C | HOH629 |
| C | HOH698 |
| C | HOH715 |
| C | HOH750 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 C 503 |
| Chain | Residue |
| A | TYR193 |
| C | THR315 |
| C | ASP316 |
| C | HIS317 |
| C | HOH668 |
| C | HOH680 |
| C | HOH682 |
| C | HOH755 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 C 504 |
| Chain | Residue |
| C | GLY458 |
| C | VAL459 |
| C | HOH756 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue GOL C 505 |
| Chain | Residue |
| C | PHE255 |
| C | ASP256 |
| C | TRP261 |
| C | ILE290 |
| C | PRO296 |
| C | HOH610 |
| C | HOH636 |
| site_id | AC9 |
| Number of Residues | 17 |
| Details | binding site for residue 7Z7 C 506 |
| Chain | Residue |
| C | LEU237 |
| C | HIS253 |
| C | CYS254 |
| C | LYS257 |
| C | SER399 |
| C | CYS400 |
| C | LYS401 |
| C | SER404 |
| C | SER423 |
| C | TRP424 |
| C | GLY425 |
| C | GLY427 |
| C | HOH601 |
| C | HOH604 |
| C | HOH613 |
| C | HOH630 |
| C | HOH658 |
| site_id | AD1 |
| Number of Residues | 2 |
| Details | binding site for residue CL C 507 |
| Chain | Residue |
| C | ARG284 |
| C | HIS309 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
| Chain | Residue | Details |
| C | VAL249-CYS254 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DSckGDSGGPHA |
| Chain | Residue | Details |
| C | ASP398-ALA409 | |
| site_id | PS01186 |
| Number of Residues | 16 |
| Details | EGF_2 EGF-like domain signature 2. CrCheGYslladgvsC |
| Chain | Residue | Details |
| A | CYS172-CYS187 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Charge relay system => ECO:0000250 |
| Chain | Residue | Details |
| C | HIS253 | |
| C | ASP302 | |
| C | SER404 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| C | ASP398 | |
| Chain | Residue | Details |
| C | ASN382 | |
