Functional Information from GO Data
| Chain | GOid | namespace | contents |
| C | 0004252 | molecular_function | serine-type endopeptidase activity |
| C | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue CA C 501 |
| Chain | Residue |
| C | GLU270 |
| C | ASP272 |
| C | GLU275 |
| C | GLU280 |
| C | HOH650 |
| C | HOH798 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 C 502 |
| Chain | Residue |
| C | HOH632 |
| C | HOH670 |
| C | HOH679 |
| C | HOH765 |
| C | MET366 |
| C | THR367 |
| C | ARG439 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 C 503 |
| Chain | Residue |
| A | HOH320 |
| C | SER453 |
| C | GLU454 |
| C | HOH688 |
| C | HOH806 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | binding site for residue 7YP C 504 |
| Chain | Residue |
| C | HIS253 |
| C | THR298 |
| C | THR299 |
| C | ASP398 |
| C | SER399 |
| C | SER404 |
| C | SER423 |
| C | TRP424 |
| C | GLY425 |
| C | GLY427 |
| C | GLY435 |
| C | HOH617 |
| C | HOH749 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
| Chain | Residue | Details |
| C | VAL249-CYS254 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DSckGDSGGPHA |
| Chain | Residue | Details |
| C | ASP398-ALA409 | |
| site_id | PS01186 |
| Number of Residues | 16 |
| Details | EGF_2 EGF-like domain signature 2. CrCheGYslladgvsC |
| Chain | Residue | Details |
| A | CYS172-CYS187 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Charge relay system => ECO:0000250 |
| Chain | Residue | Details |
| C | HIS253 | |
| C | ASP302 | |
| C | SER404 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| C | ASP398 | |
| Chain | Residue | Details |
| C | ASN382 | |
