Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0004252 | molecular_function | serine-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 301 |
| Chain | Residue |
| A | GLY196 |
| A | LYS197 |
| A | ILE198 |
| A | LEU201 |
| A | GLU202 |
| B | GLY414 |
| B | TRP416 |
| B | GOL507 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 302 |
| Chain | Residue |
| A | CYS174 |
| A | SER179 |
| A | LEU180 |
| A | HOH403 |
| A | HOH410 |
| A | HOH411 |
| B | HOH809 |
| A | ARG173 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue CA B 501 |
| Chain | Residue |
| B | GLU270 |
| B | ASP272 |
| B | GLU275 |
| B | GLU280 |
| B | HOH641 |
| B | HOH802 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue CL B 502 |
| Chain | Residue |
| B | ARG262 |
| B | VAL459 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 B 503 |
| Chain | Residue |
| B | MET366 |
| B | THR367 |
| B | ARG439 |
| B | HOH615 |
| B | HOH622 |
| B | HOH718 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 B 504 |
| Chain | Residue |
| B | HIS253 |
| B | LYS401 |
| B | GLY402 |
| B | SER404 |
| B | 7LR508 |
| B | HOH612 |
| B | HOH719 |
| B | HOH752 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 B 505 |
| Chain | Residue |
| A | HOH403 |
| B | SER453 |
| B | GLU454 |
| B | HOH701 |
| B | HOH779 |
| B | HOH809 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 506 |
| Chain | Residue |
| B | SER374 |
| B | PRO381 |
| B | HIS433 |
| B | PHE434 |
| B | HOH662 |
| site_id | AC9 |
| Number of Residues | 9 |
| Details | binding site for residue GOL B 507 |
| Chain | Residue |
| A | ILE198 |
| A | GOL301 |
| B | CYS219 |
| B | GLU223 |
| B | LEU340 |
| B | TRP416 |
| B | HOH602 |
| B | HOH649 |
| B | HOH789 |
| site_id | AD1 |
| Number of Residues | 17 |
| Details | binding site for residue 7LR B 508 |
| Chain | Residue |
| B | HIS253 |
| B | ASP256 |
| B | GLY297 |
| B | ASP302 |
| B | ASP398 |
| B | SER399 |
| B | CYS400 |
| B | SER404 |
| B | VAL422 |
| B | SER423 |
| B | TRP424 |
| B | GLY425 |
| B | GLY427 |
| B | CYS428 |
| B | SO4504 |
| B | HOH768 |
| B | HOH780 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue TFA B 509 |
| Chain | Residue |
| B | ASN300 |
| B | HIS301 |
| B | THR384 |
| B | TYR386 |
| B | HOH724 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
| Chain | Residue | Details |
| B | VAL249-CYS254 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DSckGDSGGPHA |
| Chain | Residue | Details |
| B | ASP398-ALA409 | |
| site_id | PS01186 |
| Number of Residues | 16 |
| Details | EGF_2 EGF-like domain signature 2. CrCheGYslladgvsC |
| Chain | Residue | Details |
| A | CYS172-CYS187 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19167329","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"3264725","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Charge relay system","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
