Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004252 | molecular_function | serine-type endopeptidase activity |
A | 0006508 | biological_process | proteolysis |
A | 0008236 | molecular_function | serine-type peptidase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 3 |
Details | binding site for residue SO4 A 301 |
Chain | Residue |
A | PRO172 |
A | SER173 |
A | ARG247 |
site_id | AC2 |
Number of Residues | 3 |
Details | binding site for residue SO4 A 302 |
Chain | Residue |
A | LYS237 |
A | ALA274 |
A | GLN275 |
site_id | AC3 |
Number of Residues | 4 |
Details | binding site for residue SO4 A 303 |
Chain | Residue |
A | SER260 |
A | LYS256 |
A | GLY258 |
A | ASP259 |
site_id | AC4 |
Number of Residues | 2 |
Details | binding site for residue SO4 A 304 |
Chain | Residue |
A | THR158 |
A | GLY160 |
Functional Information from PROSITE/UniProt
site_id | PS00136 |
Number of Residues | 12 |
Details | SUBTILASE_ASP Serine proteases, subtilase family, aspartic acid active site. VAVLDSGIdssH |
Chain | Residue | Details |
A | VAL28-HIS39 | |
site_id | PS00137 |
Number of Residues | 11 |
Details | SUBTILASE_HIS Serine proteases, subtilase family, histidine active site. HGThVAGtVLA |
Chain | Residue | Details |
A | HIS64-ALA74 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | ASP32 | |
A | HIS64 | |
A | ALA230 | |
site_id | SWS_FT_FI2 |
Number of Residues | 9 |
Details | BINDING: |
Chain | Residue | Details |
A | LYS2 | |
A | ASP41 | |
A | VAL75 | |
A | PRO86 | |
A | ALA88 | |
A | LEU90 | |
A | GLY178 | |
A | VAL180 | |
A | SER183 | |
Catalytic Information from CSA
site_id | MCSA1 |
Number of Residues | |
Details | M-CSA 723 |
Chain | Residue | Details |
A | ASP32 | electrostatic interaction, electrostatic stabiliser |
A | HIS64 | proton acceptor, proton donor |
A | THR164 | electrostatic interaction, electrostatic stabiliser |
A | ALA230 | nucleofuge, nucleophile, proton acceptor, proton donor |