5OWO
Human cytoplasmic Dynein N-Terminus dimerization domain at 1.8 Angstrom resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0007018 | biological_process | microtubule-based movement |
| A | 0030286 | cellular_component | dynein complex |
| A | 0045505 | molecular_function | dynein intermediate chain binding |
| A | 0051959 | molecular_function | dynein light intermediate chain binding |
| B | 0007018 | biological_process | microtubule-based movement |
| B | 0030286 | cellular_component | dynein complex |
| B | 0045505 | molecular_function | dynein intermediate chain binding |
| B | 0051959 | molecular_function | dynein light intermediate chain binding |
| C | 0007018 | biological_process | microtubule-based movement |
| C | 0030286 | cellular_component | dynein complex |
| C | 0045505 | molecular_function | dynein intermediate chain binding |
| C | 0051959 | molecular_function | dynein light intermediate chain binding |
| D | 0007018 | biological_process | microtubule-based movement |
| D | 0030286 | cellular_component | dynein complex |
| D | 0045505 | molecular_function | dynein intermediate chain binding |
| D | 0051959 | molecular_function | dynein light intermediate chain binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 301 |
| Chain | Residue |
| A | ALA51 |
| A | GLU97 |
| A | PHE98 |
| A | ILE99 |
| A | MG305 |
| C | PHE98 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 302 |
| Chain | Residue |
| A | SER154 |
| A | ASN155 |
| D | HIS75 |
| A | GLU147 |
| A | HIS150 |
| A | SER151 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 303 |
| Chain | Residue |
| A | ALA127 |
| A | ASP128 |
| A | LYS129 |
| A | PRO130 |
| A | HIS195 |
| A | MG307 |
| A | HOH441 |
| D | ASP44 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 304 |
| Chain | Residue |
| A | ASN104 |
| A | ASP106 |
| A | HIS108 |
| A | HOH468 |
| A | HOH471 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 305 |
| Chain | Residue |
| A | PRO49 |
| A | ALA50 |
| A | ALA51 |
| A | GOL301 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue MG A 306 |
| Chain | Residue |
| A | THR83 |
| A | LYS112 |
| A | HOH458 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue MG A 307 |
| Chain | Residue |
| A | GLN198 |
| A | GOL303 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | binding site for residue MG A 308 |
| Chain | Residue |
| A | PHE152 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue MG A 309 |
| Chain | Residue |
| A | GLU58 |
| A | LYS59 |
| C | GLU80 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 310 |
| Chain | Residue |
| A | SER132 |
| A | LEU135 |
| A | VAL137 |
| A | HOH459 |
| D | THR139 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 311 |
| Chain | Residue |
| A | VAL29 |
| A | HIS195 |
| A | GLN198 |
| A | ASN199 |
| A | HOH467 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 312 |
| Chain | Residue |
| A | GLU58 |
| A | ASN102 |
| A | HOH420 |
| C | GLU58 |
| C | ASN102 |
| C | HOH415 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 301 |
| Chain | Residue |
| B | ALA51 |
| B | GLU97 |
| B | PHE98 |
| B | ILE99 |
| B | HOH449 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 302 |
| Chain | Residue |
| B | THR122 |
| B | PRO123 |
| B | MG304 |
| B | HOH414 |
| C | GOL302 |
| site_id | AD6 |
| Number of Residues | 2 |
| Details | binding site for residue GOL B 303 |
| Chain | Residue |
| B | GLU147 |
| B | HOH401 |
| site_id | AD7 |
| Number of Residues | 3 |
| Details | binding site for residue MG B 304 |
| Chain | Residue |
| B | PRO72 |
| B | HIS75 |
| B | GOL302 |
| site_id | AD8 |
| Number of Residues | 3 |
| Details | binding site for residue MG B 305 |
| Chain | Residue |
| B | SER154 |
| B | ALA158 |
| B | GLU190 |
| site_id | AD9 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 306 |
| Chain | Residue |
| B | LYS162 |
| B | GLU183 |
| B | ALA187 |
| B | HOH411 |
| B | HOH443 |
| site_id | AE1 |
| Number of Residues | 3 |
| Details | binding site for residue MG B 307 |
| Chain | Residue |
| B | LYS32 |
| B | ARG35 |
| B | HOH444 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 308 |
| Chain | Residue |
| B | HIS195 |
| B | GLN198 |
| B | ASN199 |
| D | VAL29 |
| D | HOH460 |
| site_id | AE3 |
| Number of Residues | 3 |
| Details | binding site for residue MG B 309 |
| Chain | Residue |
| B | TYR164 |
| C | SER144 |
| C | ILE200 |
| site_id | AE4 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 310 |
| Chain | Residue |
| B | LEU78 |
| B | ASN104 |
| B | ASP106 |
| B | HIS108 |
| B | HOH451 |
| site_id | AE5 |
| Number of Residues | 1 |
| Details | binding site for residue MG B 311 |
| Chain | Residue |
| D | ASP128 |
| site_id | AE6 |
| Number of Residues | 6 |
| Details | binding site for residue NA B 312 |
| Chain | Residue |
| B | HOH421 |
| B | GLU58 |
| B | GLU58 |
| B | ASN102 |
| B | ASN102 |
| B | HOH421 |
| site_id | AE7 |
| Number of Residues | 5 |
| Details | binding site for residue GOL C 301 |
| Chain | Residue |
| C | ALA51 |
| C | GLU97 |
| C | PHE98 |
| C | ILE99 |
| C | MG303 |
| site_id | AE8 |
| Number of Residues | 8 |
| Details | binding site for residue GOL C 302 |
| Chain | Residue |
| B | HIS75 |
| B | GOL302 |
| B | HOH414 |
| C | GLU147 |
| C | HIS150 |
| C | SER151 |
| C | SER154 |
| C | ASN155 |
| site_id | AE9 |
| Number of Residues | 4 |
| Details | binding site for residue MG C 303 |
| Chain | Residue |
| C | PRO49 |
| C | ALA50 |
| C | ALA51 |
| C | GOL301 |
| site_id | AF1 |
| Number of Residues | 5 |
| Details | binding site for residue MG C 304 |
| Chain | Residue |
| C | THR83 |
| C | LYS112 |
| C | ASN114 |
| C | GLU142 |
| C | HOH451 |
| site_id | AF2 |
| Number of Residues | 2 |
| Details | binding site for residue MG C 305 |
| Chain | Residue |
| C | PRO72 |
| C | PRO123 |
| site_id | AF3 |
| Number of Residues | 3 |
| Details | binding site for residue MG C 307 |
| Chain | Residue |
| C | ASP26 |
| C | VAL29 |
| C | HOH405 |
| site_id | AF4 |
| Number of Residues | 1 |
| Details | binding site for residue MG C 308 |
| Chain | Residue |
| C | HIS75 |
| site_id | AF5 |
| Number of Residues | 2 |
| Details | binding site for residue MG C 309 |
| Chain | Residue |
| C | THR122 |
| C | VAL124 |
| site_id | AF6 |
| Number of Residues | 5 |
| Details | binding site for residue GOL D 301 |
| Chain | Residue |
| D | ALA51 |
| D | GLU97 |
| D | PHE98 |
| D | ILE99 |
| D | MG302 |
| site_id | AF7 |
| Number of Residues | 4 |
| Details | binding site for residue MG D 302 |
| Chain | Residue |
| D | PRO49 |
| D | ALA50 |
| D | ALA51 |
| D | GOL301 |
| site_id | AF8 |
| Number of Residues | 4 |
| Details | binding site for residue MG D 303 |
| Chain | Residue |
| D | GLY110 |
| D | VAL111 |
| D | LYS112 |
| D | SER113 |
| site_id | AF9 |
| Number of Residues | 3 |
| Details | binding site for residue MG D 304 |
| Chain | Residue |
| D | PRO72 |
| D | HIS75 |
| D | HOH466 |
| site_id | AG1 |
| Number of Residues | 6 |
| Details | binding site for residue CA D 305 |
| Chain | Residue |
| D | GLU58 |
| D | GLU58 |
| D | ASN102 |
| D | ASN102 |
| D | HOH412 |
| D | HOH412 |
| site_id | AG2 |
| Number of Residues | 8 |
| Details | binding site for residue K D 306 |
| Chain | Residue |
| D | SER60 |
| D | SER60 |
| D | ASN102 |
| D | ASN102 |
| D | HOH404 |
| D | HOH404 |
| D | HOH418 |
| D | HOH418 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
