5OVQ

Crystal Structure of the peroxiredoxin (AhpC2) from the Hyperthermophilic bacteria Aquifex aeolicus VF

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004601	molecular_function	peroxidase activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0016209	molecular_function	antioxidant activity
A	0016491	molecular_function	oxidoreductase activity
A	0045454	biological_process	cell redox homeostasis
A	0051920	molecular_function	peroxiredoxin activity
A	0098869	biological_process	cellular oxidant detoxification
A	0140824	molecular_function	thioredoxin-dependent peroxiredoxin activity
B	0004601	molecular_function	peroxidase activity
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0016209	molecular_function	antioxidant activity
B	0016491	molecular_function	oxidoreductase activity
B	0045454	biological_process	cell redox homeostasis
B	0051920	molecular_function	peroxiredoxin activity
B	0098869	biological_process	cellular oxidant detoxification
B	0140824	molecular_function	thioredoxin-dependent peroxiredoxin activity
C	0004601	molecular_function	peroxidase activity
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0016209	molecular_function	antioxidant activity
C	0016491	molecular_function	oxidoreductase activity
C	0045454	biological_process	cell redox homeostasis
C	0051920	molecular_function	peroxiredoxin activity
C	0098869	biological_process	cellular oxidant detoxification
C	0140824	molecular_function	thioredoxin-dependent peroxiredoxin activity
D	0004601	molecular_function	peroxidase activity
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0016209	molecular_function	antioxidant activity
D	0016491	molecular_function	oxidoreductase activity
D	0045454	biological_process	cell redox homeostasis
D	0051920	molecular_function	peroxiredoxin activity
D	0098869	biological_process	cellular oxidant detoxification
D	0140824	molecular_function	thioredoxin-dependent peroxiredoxin activity
E	0004601	molecular_function	peroxidase activity
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0016209	molecular_function	antioxidant activity
E	0016491	molecular_function	oxidoreductase activity
E	0045454	biological_process	cell redox homeostasis
E	0051920	molecular_function	peroxiredoxin activity
E	0098869	biological_process	cellular oxidant detoxification
E	0140824	molecular_function	thioredoxin-dependent peroxiredoxin activity
F	0004601	molecular_function	peroxidase activity
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0016209	molecular_function	antioxidant activity
F	0016491	molecular_function	oxidoreductase activity
F	0045454	biological_process	cell redox homeostasis
F	0051920	molecular_function	peroxiredoxin activity
F	0098869	biological_process	cellular oxidant detoxification
F	0140824	molecular_function	thioredoxin-dependent peroxiredoxin activity
G	0004601	molecular_function	peroxidase activity
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0016209	molecular_function	antioxidant activity
G	0016491	molecular_function	oxidoreductase activity
G	0045454	biological_process	cell redox homeostasis
G	0051920	molecular_function	peroxiredoxin activity
G	0098869	biological_process	cellular oxidant detoxification
G	0140824	molecular_function	thioredoxin-dependent peroxiredoxin activity
H	0004601	molecular_function	peroxidase activity
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0016209	molecular_function	antioxidant activity
H	0016491	molecular_function	oxidoreductase activity
H	0045454	biological_process	cell redox homeostasis
H	0051920	molecular_function	peroxiredoxin activity
H	0098869	biological_process	cellular oxidant detoxification
H	0140824	molecular_function	thioredoxin-dependent peroxiredoxin activity
I	0004601	molecular_function	peroxidase activity
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0016209	molecular_function	antioxidant activity
I	0016491	molecular_function	oxidoreductase activity
I	0045454	biological_process	cell redox homeostasis
I	0051920	molecular_function	peroxiredoxin activity
I	0098869	biological_process	cellular oxidant detoxification
I	0140824	molecular_function	thioredoxin-dependent peroxiredoxin activity
J	0004601	molecular_function	peroxidase activity
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0016209	molecular_function	antioxidant activity
J	0016491	molecular_function	oxidoreductase activity
J	0045454	biological_process	cell redox homeostasis
J	0051920	molecular_function	peroxiredoxin activity
J	0098869	biological_process	cellular oxidant detoxification
J	0140824	molecular_function	thioredoxin-dependent peroxiredoxin activity
K	0004601	molecular_function	peroxidase activity
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0016209	molecular_function	antioxidant activity
K	0016491	molecular_function	oxidoreductase activity
K	0045454	biological_process	cell redox homeostasis
K	0051920	molecular_function	peroxiredoxin activity
K	0098869	biological_process	cellular oxidant detoxification
K	0140824	molecular_function	thioredoxin-dependent peroxiredoxin activity
L	0004601	molecular_function	peroxidase activity
L	0005737	cellular_component	cytoplasm
L	0005829	cellular_component	cytosol
L	0016209	molecular_function	antioxidant activity
L	0016491	molecular_function	oxidoreductase activity
L	0045454	biological_process	cell redox homeostasis
L	0051920	molecular_function	peroxiredoxin activity
L	0098869	biological_process	cellular oxidant detoxification
L	0140824	molecular_function	thioredoxin-dependent peroxiredoxin activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue UNL A 301

Chain	Residue
A	PRO42
A	THR46
A	OCS49
A	LEU145
A	PRO195
A	HOH511
A	HOH583

---

site_id	AC2
Number of Residues	6
Details	binding site for residue UNL B 301

Chain	Residue
B	OCS49
B	ARG126
B	LEU145
B	HOH478
B	PRO42
B	THR46

---

site_id	AC3
Number of Residues	5
Details	binding site for residue UNL D 301

Chain	Residue
D	PRO42
D	THR46
D	OCS49
D	LEU145
D	PRO195

---

site_id	AC4
Number of Residues	5
Details	binding site for residue UNL E 301

Chain	Residue
E	PRO42
E	THR46
E	OCS49
E	LEU145
H	PHE79

---

site_id	AC5
Number of Residues	6
Details	binding site for residue UNL F 301

Chain	Residue
F	PRO42
F	THR46
F	OCS49
F	LEU145
F	HOH455
F	HOH476

---

site_id	AC6
Number of Residues	4
Details	binding site for residue UNL G 301

Chain	Residue
G	PRO42
G	THR46
G	OCS49
G	HOH463

---

site_id	AC7
Number of Residues	4
Details	binding site for residue UNL H 301

Chain	Residue
H	THR46
H	OCS49
H	PRO195
H	HOH515

---

site_id	AC8
Number of Residues	6
Details	binding site for residue UNL I 301

Chain	Residue
I	PRO42
I	THR46
I	OCS49
I	LEU145
I	PRO195
I	HOH495

---

site_id	AC9
Number of Residues	8
Details	binding site for residue UNL J 301

Chain	Residue
J	PRO42
J	THR46
J	OCS49
J	LEU145
J	PRO195
J	HOH465
J	HOH481
K	PHE79

---

site_id	AD1
Number of Residues	8
Details	binding site for residue UNL K 301

Chain	Residue
J	PHE79
K	PRO42
K	THR46
K	OCS49
K	ARG126
K	HOH434
K	HOH473
K	HOH511

---

site_id	AD2
Number of Residues	4
Details	binding site for residue UNL L 301

Chain	Residue
L	THR46
L	OCS49
L	PRO195
L	HOH444

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	Active site: {"description":"Cysteine sulfenic acid (-SOH) intermediate","evidences":[{"source":"HAMAP-Rule","id":"MF_00401","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00401","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---