Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005085 | molecular_function | guanyl-nucleotide exchange factor activity |
| A | 0007264 | biological_process | small GTPase-mediated signal transduction |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue AXH A 2001 |
| Chain | Residue |
| A | ASN879 |
| A | HOH2296 |
| A | VAL883 |
| A | TYR884 |
| A | LEU886 |
| A | ASP887 |
| A | PHE890 |
| A | GLU902 |
| A | HIS905 |
| A | EDO2004 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 2002 |
| Chain | Residue |
| A | ASP775 |
| A | TYR1031 |
| A | HOH2140 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 2003 |
| Chain | Residue |
| A | ARG786 |
| A | GLU864 |
| A | PRO1042 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 2004 |
| Chain | Residue |
| A | TYR884 |
| A | ARG950 |
| A | AXH2001 |
| A | HOH2139 |
| A | HOH2184 |
Functional Information from PROSITE/UniProt
| site_id | PS00720 |
| Number of Residues | 34 |
| Details | RASGEF Ras Guanine-nucleotide exchange factors domain signature. VPFfGiyLtNIlkteegnpevlkrhgkel.................INFsK |
| Chain | Residue | Details |
| A | VAL927-LYS960 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 144 |
| Details | Domain: {"description":"N-terminal Ras-GEF","evidences":[{"source":"PROSITE-ProRule","id":"PRU00135","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 239 |
| Details | Domain: {"description":"Ras-GEF","evidences":[{"source":"PROSITE-ProRule","id":"PRU00168","evidenceCode":"ECO:0000255"}]} |
