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5OV8

Crystal structure of the human BRPF1 bromodomain in complex with BZ097

Functional Information from PDB Data
site_idAC1
Number of Residues12
Detailsbinding site for residue AXN A 801
ChainResidue
AILE652
AHOH917
BLYS639
BGLU642
AVAL657
APRO658
AGLU661
ACYS704
ATYR707
AASN708
APHE714
AHOH916

site_idAC2
Number of Residues8
Detailsbinding site for residue NO3 A 802
ChainResidue
AGLU694
ALEU729
AARG730
AARG733
AHOH901
BASP691
BGLU694
BARG733

site_idAC3
Number of Residues13
Detailsbinding site for residue AXN B 801
ChainResidue
AILE635
ALYS639
BILE652
BPHE653
BVAL657
BPRO658
BGLU661
BVAL662
BCYS704
BTYR707
BASN708
BPHE714
BHOH919

Functional Information from PROSITE/UniProt
site_idPS00633
Number of Residues58
DetailsBROMODOMAIN_1 Bromodomain signature. GniFsepvPlsevp..DYLdhIkkpMdfftMkqnleayr..Ylnfddfeedfnl.IvsNClkY
ChainResidueDetails
AGLY650-TYR707

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PDB entries from 2024-11-06

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