5OTV
Extracellular domain of GLP-1 receptor in complex with GLP-1 variant Ala8Cyc/Thr11Hcs
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004930 | molecular_function | G protein-coupled receptor activity |
| A | 0004967 | molecular_function | glucagon receptor activity |
| A | 0007186 | biological_process | G protein-coupled receptor signaling pathway |
| A | 0008528 | molecular_function | G protein-coupled peptide receptor activity |
| A | 0016020 | cellular_component | membrane |
| B | 0005179 | molecular_function | hormone activity |
| B | 0005576 | cellular_component | extracellular region |
| C | 0004930 | molecular_function | G protein-coupled receptor activity |
| C | 0004967 | molecular_function | glucagon receptor activity |
| C | 0007186 | biological_process | G protein-coupled receptor signaling pathway |
| C | 0008528 | molecular_function | G protein-coupled peptide receptor activity |
| C | 0016020 | cellular_component | membrane |
| D | 0005179 | molecular_function | hormone activity |
| D | 0005576 | cellular_component | extracellular region |
Functional Information from PROSITE/UniProt
| site_id | PS00649 |
| Number of Residues | 25 |
| Details | G_PROTEIN_RECEP_F2_1 G-protein coupled receptors family 2 signature 1. CnrtFDeya.CWpdGepgsfvnvsCP |
| Chain | Residue | Details |
| C | CYS62-PRO86 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Site: {"description":"Interaction with the endogenous ligand GLP-1","evidences":[{"source":"PubMed","id":"19861722","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 5 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"22412906","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P55095","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
