Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003723 | molecular_function | RNA binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005759 | cellular_component | mitochondrial matrix |
| A | 0005829 | cellular_component | cytosol |
| A | 0008413 | molecular_function | 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity |
| A | 0008828 | molecular_function | dATP diphosphatase activity |
| A | 0009151 | biological_process | purine deoxyribonucleotide metabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016791 | molecular_function | phosphatase activity |
| A | 0016818 | molecular_function | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides |
| A | 0042262 | biological_process | DNA protection |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0047429 | molecular_function | nucleoside triphosphate diphosphatase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | binding site for residue 6OG A 201 |
| Chain | Residue |
| A | THR8 |
| A | GLU100 |
| A | TRP117 |
| A | ASP119 |
| A | ASP120 |
| A | GOL202 |
| A | GOL205 |
| A | CA211 |
| A | HOH344 |
| A | HOH387 |
| A | HOH428 |
| A | LEU9 |
| A | LYS23 |
| A | ASN33 |
| A | GLY36 |
| A | GLY37 |
| A | LYS38 |
| A | PHE72 |
| A | MET81 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 202 |
| Chain | Residue |
| A | LYS5 |
| A | LYS38 |
| A | LEU54 |
| A | 6OG201 |
| A | HOH357 |
| A | HOH376 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 203 |
| Chain | Residue |
| A | VAL39 |
| A | THR41 |
| A | LEU122 |
| A | LEU126 |
| A | LEU150 |
| A | GOL204 |
| A | HOH352 |
| A | HOH360 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | binding site for residue GOL A 204 |
| Chain | Residue |
| A | SER4 |
| A | GLU79 |
| A | PRO125 |
| A | LEU126 |
| A | GLN129 |
| A | LYS131 |
| A | GOL203 |
| A | HOH352 |
| A | HOH353 |
| A | HOH389 |
| site_id | AC5 |
| Number of Residues | 12 |
| Details | binding site for residue GOL A 205 |
| Chain | Residue |
| A | LYS23 |
| A | ARG25 |
| A | GLY26 |
| A | PHE27 |
| A | VAL61 |
| A | ASP62 |
| A | GLU92 |
| A | GLU100 |
| A | 6OG201 |
| A | CA213 |
| A | CL217 |
| A | HOH428 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 206 |
| Chain | Residue |
| A | PHE2 |
| A | GLN14 |
| A | GLY16 |
| A | LEU128 |
| A | LYS130 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 207 |
| Chain | Residue |
| A | GLN14 |
| A | GLN40 |
| A | ARG51 |
| A | ASN90 |
| A | TYR91 |
| A | HOH307 |
| A | HOH309 |
| A | HOH410 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 208 |
| Chain | Residue |
| A | THR44 |
| A | ILE45 |
| A | ALA118 |
| A | ILE121 |
| A | HOH361 |
| A | HOH377 |
| A | HOH416 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 209 |
| Chain | Residue |
| A | SER114 |
| A | ASP155 |
| A | LEU156 |
| A | HOH340 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 210 |
| Chain | Residue |
| A | PRO95 |
| A | PRO103 |
| A | GLU152 |
| A | HOH398 |
| A | HOH403 |
| A | HOH413 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 211 |
| Chain | Residue |
| A | GLY36 |
| A | GLU56 |
| A | GLU100 |
| A | 6OG201 |
| A | HOH426 |
| A | HOH428 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 212 |
| Chain | Residue |
| A | GLU52 |
| A | GLU55 |
| A | ASP62 |
| A | GLU92 |
| A | HOH331 |
| A | HOH397 |
| site_id | AD4 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 213 |
| Chain | Residue |
| A | GLU100 |
| A | GOL205 |
| A | HOH331 |
| A | HOH428 |
| A | ASP62 |
| A | GLU92 |
| site_id | AD5 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 214 |
| Chain | Residue |
| A | LEU128 |
| A | GLN129 |
| A | HOH355 |
| site_id | AD6 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 215 |
| Chain | Residue |
| A | LYS66 |
| A | ASN69 |
| A | SER114 |
| A | LEU134 |
| A | LEU156 |
| A | EDO216 |
| A | HOH439 |
| site_id | AD7 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 216 |
| Chain | Residue |
| A | PRO112 |
| A | PHE113 |
| A | SER114 |
| A | GLN115 |
| A | EDO215 |
| A | HOH439 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 217 |
| Chain | Residue |
| A | GLY26 |
| A | ARG50 |
| A | GOL205 |
| A | HOH444 |
Functional Information from PROSITE/UniProt
| site_id | PS00893 |
| Number of Residues | 22 |
| Details | NUDIX_BOX Nudix box signature. GkvqtgEtieqAArRELlEEsG |
| Chain | Residue | Details |
| A | GLY37-GLY58 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 129 |
| Details | Domain: {"description":"Nudix hydrolase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00794","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 21 |
| Details | Motif: {"description":"Nudix box","evidences":[{"source":"PROSITE-ProRule","id":"PRU00794","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"30304478","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5OTN","evidenceCode":"ECO:0007744"}]} |
