Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004067 | molecular_function | asparaginase activity |
A | 0006520 | biological_process | amino acid metabolic process |
A | 0016787 | molecular_function | hydrolase activity |
B | 0004067 | molecular_function | asparaginase activity |
B | 0006520 | biological_process | amino acid metabolic process |
B | 0016787 | molecular_function | hydrolase activity |
C | 0004067 | molecular_function | asparaginase activity |
C | 0006520 | biological_process | amino acid metabolic process |
C | 0016787 | molecular_function | hydrolase activity |
D | 0004067 | molecular_function | asparaginase activity |
D | 0006520 | biological_process | amino acid metabolic process |
D | 0016787 | molecular_function | hydrolase activity |
E | 0004067 | molecular_function | asparaginase activity |
E | 0006520 | biological_process | amino acid metabolic process |
E | 0016787 | molecular_function | hydrolase activity |
F | 0004067 | molecular_function | asparaginase activity |
F | 0006520 | biological_process | amino acid metabolic process |
F | 0016787 | molecular_function | hydrolase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 9 |
Details | binding site for residue PO4 A 401 |
Chain | Residue |
A | GLY10 |
A | THR11 |
A | ASP53 |
A | SER54 |
A | GLY84 |
A | THR85 |
A | ASP86 |
A | HOH505 |
A | HOH524 |
site_id | AC2 |
Number of Residues | 9 |
Details | binding site for residue EDO A 402 |
Chain | Residue |
A | ASN169 |
A | ALA264 |
A | LEU265 |
A | TYR266 |
A | GLY267 |
A | GLY268 |
A | MET291 |
A | LYS293 |
A | HOH531 |
site_id | AC3 |
Number of Residues | 11 |
Details | binding site for residue PO4 B 401 |
Chain | Residue |
A | TYR274 |
B | GLY10 |
B | THR11 |
B | ASP53 |
B | SER54 |
B | GLY84 |
B | THR85 |
B | ASP86 |
B | HOH507 |
B | HOH510 |
B | HOH516 |
site_id | AC4 |
Number of Residues | 9 |
Details | binding site for residue EDO B 402 |
Chain | Residue |
B | ASN169 |
B | ALA264 |
B | LEU265 |
B | TYR266 |
B | GLY267 |
B | GLY268 |
B | MET291 |
B | LYS293 |
B | HOH526 |
site_id | AC5 |
Number of Residues | 7 |
Details | binding site for residue EDO B 403 |
Chain | Residue |
B | GLY7 |
B | ALA13 |
B | LEU25 |
B | ASP48 |
B | LEU50 |
B | ASN51 |
B | HOH511 |
site_id | AC6 |
Number of Residues | 8 |
Details | binding site for residue PG4 B 404 |
Chain | Residue |
B | ASP28 |
B | GLU45 |
B | THR46 |
B | ASP48 |
D | ILE49 |
D | LEU50 |
D | ASN51 |
D | EDO402 |
site_id | AC7 |
Number of Residues | 7 |
Details | binding site for residue PO4 C 401 |
Chain | Residue |
C | GLY10 |
C | THR11 |
C | SER54 |
C | GLY84 |
C | THR85 |
C | ASP86 |
D | TYR274 |
site_id | AC8 |
Number of Residues | 9 |
Details | binding site for residue PO4 D 401 |
Chain | Residue |
C | TYR274 |
D | GLY10 |
D | THR11 |
D | ASP53 |
D | SER54 |
D | GLY84 |
D | THR85 |
D | ASP86 |
D | HOH504 |
site_id | AC9 |
Number of Residues | 10 |
Details | binding site for residue EDO D 402 |
Chain | Residue |
B | PG4404 |
D | GLY9 |
D | ALA13 |
D | ALA24 |
D | LEU25 |
D | ASP48 |
D | LEU50 |
D | ASN51 |
D | HOH502 |
D | HOH510 |
site_id | AD1 |
Number of Residues | 9 |
Details | binding site for residue EDO D 403 |
Chain | Residue |
D | ASN169 |
D | ALA264 |
D | LEU265 |
D | TYR266 |
D | GLY267 |
D | GLY268 |
D | MET291 |
D | LYS293 |
D | HOH528 |
site_id | AD2 |
Number of Residues | 9 |
Details | binding site for residue PO4 E 401 |
Chain | Residue |
E | GLY10 |
E | THR11 |
E | SER54 |
E | GLY84 |
E | THR85 |
E | ASP86 |
E | HOH504 |
E | HOH514 |
F | TYR274 |
site_id | AD3 |
Number of Residues | 7 |
Details | binding site for residue PO4 F 401 |
Chain | Residue |
F | THR11 |
F | SER54 |
F | GLY84 |
F | THR85 |
F | ASP86 |
E | TYR274 |
F | GLY10 |
site_id | AD4 |
Number of Residues | 8 |
Details | binding site for residue EDO F 402 |
Chain | Residue |
F | ASN169 |
F | THR262 |
F | ALA264 |
F | LEU265 |
F | TYR266 |
F | GLY267 |
F | GLY268 |
F | LYS293 |
Functional Information from PROSITE/UniProt
site_id | PS00144 |
Number of Residues | 9 |
Details | ASN_GLN_ASE_1 Asparaginase / glutaminase active site signature 1. VlGTGGTIA |
Chain | Residue | Details |
A | VAL5-ALA13 | |
site_id | PS00917 |
Number of Residues | 11 |
Details | ASN_GLN_ASE_2 Asparaginase / glutaminase active site signature 2. GiVitHGTDTL |
Chain | Residue | Details |
A | GLY78-LEU88 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | THR11 | |
B | THR11 | |
C | THR11 | |
D | THR11 | |
E | THR11 | |
F | THR11 | |
Chain | Residue | Details |
A | THR85 | |
C | ASP86 | |
C | LYS156 | |
C | TYR274 | |
D | THR85 | |
D | ASP86 | |
D | LYS156 | |
D | TYR274 | |
E | THR85 | |
E | ASP86 | |
E | LYS156 | |
A | ASP86 | |
E | TYR274 | |
F | THR85 | |
F | ASP86 | |
F | LYS156 | |
F | TYR274 | |
A | LYS156 | |
A | TYR274 | |
B | THR85 | |
B | ASP86 | |
B | LYS156 | |
B | TYR274 | |
C | THR85 | |
Chain | Residue | Details |
A | THR11 | |
B | ASP86 | |
C | THR11 | |
C | ASP53 | |
C | SER54 | |
C | THR85 | |
C | ASP86 | |
D | THR11 | |
D | ASP53 | |
D | SER54 | |
D | THR85 | |
A | ASP53 | |
D | ASP86 | |
E | THR11 | |
E | ASP53 | |
E | SER54 | |
E | THR85 | |
E | ASP86 | |
F | THR11 | |
F | ASP53 | |
F | SER54 | |
F | THR85 | |
A | SER54 | |
F | ASP86 | |
A | THR85 | |
A | ASP86 | |
B | THR11 | |
B | ASP53 | |
B | SER54 | |
B | THR85 | |