English 日本語简体中文繁體中文 한국어

✖

Menu

RCSB PDB PDBe BMRB Adv. Search Search help

Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5OLZ

Structure of the A2A-StaR2-bRIL562-Compound 4e complex at 1.9A obtained from bespoke co-crystallisation experiments.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001609	molecular_function	G protein-coupled adenosine receptor activity
A	0001973	biological_process	G protein-coupled adenosine receptor signaling pathway
A	0004930	molecular_function	G protein-coupled receptor activity
A	0005506	molecular_function	iron ion binding
A	0007186	biological_process	G protein-coupled receptor signaling pathway
A	0009055	molecular_function	electron transfer activity
A	0016020	cellular_component	membrane
A	0020037	molecular_function	heme binding
A	0022900	biological_process	electron transport chain
A	0042597	cellular_component	periplasmic space
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	binding site for residue T4E A 1201

Chain	Residue
A	ALA63
A	HIS278
A	HOH1309
A	HOH1355
A	VAL84
A	LEU85
A	PHE168
A	GLU169
A	MET177
A	TRP246
A	HIS250
A	ASN253

site_id	AC2
Number of Residues	5
Details	binding site for residue CLR A 1202

Chain	Residue
A	HIS75
A	GLY76
A	OLC1229
A	HOH1305
A	HOH1326

site_id	AC3
Number of Residues	8
Details	binding site for residue CLR A 1203

Chain	Residue
A	ALA72
A	ALA73
A	GLY76
A	ILE80
A	CLR1205
A	OLC1221
A	OLC1225
A	OLC1226

site_id	AC4
Number of Residues	5
Details	binding site for residue CLR A 1204

Chain	Residue
A	PRO248
A	CYS262
A	SER263
A	OLA1218
A	OLC1223

site_id	AC5
Number of Residues	7
Details	binding site for residue CLR A 1205

Chain	Residue
A	CYS254
A	PHE255
A	PHE258
A	CYS259
A	CLR1203
A	OLC1225
A	HOH1344

site_id	AC6
Number of Residues	1
Details	binding site for residue OLA A 1206

Chain	Residue
A	THR65

site_id	AC7
Number of Residues	3
Details	binding site for residue OLA A 1207

Chain	Residue
A	PHE44
A	ALA97
A	VAL116

site_id	AC8
Number of Residues	5
Details	binding site for residue OLA A 1208

Chain	Residue
A	GLY123
A	LEU131
A	VAL188
A	OLC1224
A	HOH1356

site_id	AC9
Number of Residues	5
Details	binding site for residue OLA A 1209

Chain	Residue
A	GLY5
A	TYR271
A	VAL275
A	OLA1213
A	OLA1214

site_id	AD1
Number of Residues	1
Details	binding site for residue OLA A 1210

Chain	Residue
A	OLC1228

site_id	AD2
Number of Residues	3
Details	binding site for residue OLA A 1211

Chain	Residue
A	SER7
A	LEU26
A	PHE286

site_id	AD3
Number of Residues	2
Details	binding site for residue OLA A 1212

Chain	Residue
A	TRP268
A	LEU272

site_id	AD4
Number of Residues	2
Details	binding site for residue OLA A 1213

Chain	Residue
A	OLA1209
A	OLA1214

site_id	AD5
Number of Residues	4
Details	binding site for residue OLA A 1214

Chain	Residue
A	THR279
A	VAL283
A	OLA1209
A	OLA1213

site_id	AD6
Number of Residues	3
Details	binding site for residue OLA A 1215

Chain	Residue
A	LEU190
A	ALA236
A	OLA1217

site_id	AD7
Number of Residues	4
Details	binding site for residue OLA A 1216

Chain	Residue
A	TRP29
A	TRP32
A	PHE201
A	LYS233

site_id	AD8
Number of Residues	2
Details	binding site for residue OLA A 1217

Chain	Residue
A	LEU244
A	OLA1215

site_id	AD9
Number of Residues	2
Details	binding site for residue OLA A 1218

Chain	Residue
A	LEU244
A	CLR1204

site_id	AE1
Number of Residues	2
Details	binding site for residue OLA A 1219

Chain	Residue
A	TRP268
A	LEU272

site_id	AE2
Number of Residues	4
Details	binding site for residue OLC A 1220

Chain	Residue
A	TYR179
A	OLC1221
A	OLC1222
A	OLC1229

site_id	AE3
Number of Residues	8
Details	binding site for residue OLC A 1221

Chain	Residue
A	GLN163
A	PHE183
A	PHE258
A	CLR1203
A	OLC1220
A	HOH1305
A	HOH1348
A	HOH1380

site_id	AE4
Number of Residues	10
Details	binding site for residue OLC A 1222

Chain	Residue
A	HIS75
A	MET140
A	LEU141
A	GLY142
A	ASN144
A	TYR179
A	OLC1220
A	OLC1229
A	HOH1301
A	HOH1311

site_id	AE5
Number of Residues	6
Details	binding site for residue OLC A 1223

Chain	Residue
A	SER263
A	LYS1085
A	CLR1204
A	OLC1225
A	HOH1302
A	ASP261

site_id	AE6
Number of Residues	3
Details	binding site for residue OLC A 1224

Chain	Residue
A	ARG120
A	PHE180
A	OLA1208

site_id	AE7
Number of Residues	7
Details	binding site for residue OLC A 1225

Chain	Residue
A	THR65
A	PHE70
A	CYS71
A	CLR1203
A	CLR1205
A	OLC1223
A	HOH1375

site_id	AE8
Number of Residues	7
Details	binding site for residue OLC A 1226

Chain	Residue
A	TYR43
A	LEU58
A	PHE83
A	ILE125
A	TRP129
A	PHE133
A	CLR1203

site_id	AE9
Number of Residues	5
Details	binding site for residue OLC A 1227

Chain	Residue
A	CYS28
A	VAL31
A	TYR43
A	LEU54
A	ARG205

site_id	AF1
Number of Residues	6
Details	binding site for residue OLC A 1228

Chain	Residue
A	SER6
A	ILE10
A	SER67
A	THR68
A	GLN157
A	OLA1210

site_id	AF2
Number of Residues	6
Details	binding site for residue OLC A 1229

Chain	Residue
A	HIS75
A	MET140
A	CLR1202
A	OLC1220
A	OLC1222
A	OLC1230

site_id	AF3
Number of Residues	1
Details	binding site for residue OLC A 1230

Chain	Residue
A	OLC1229

site_id	AF4
Number of Residues	10
Details	binding site for residue TAR A 1231

Chain	Residue
A	GLY142
A	GLY142
A	TRP143
A	TRP143
A	ASN144
A	ASN144
A	ASN145
A	ASN145
A	ASN175
A	ASN175

site_id	AF5
Number of Residues	3
Details	binding site for residue OLA A 1232

Chain	Residue
A	SER7
A	THR11
A	THR11

site_id	AF6
Number of Residues	5
Details	binding site for residue PGE A 1233

Chain	Residue
A	HIS264
A	ALA265
A	PRO266
A	LEU267
A	HOH1308

site_id	AF7
Number of Residues	5
Details	binding site for residue NA A 1234

Chain	Residue
A	ASP52
A	SER91
A	HOH1343
A	HOH1368
A	HOH1376

Functional Information from PROSITE/UniProt

site_id	PS00237
Number of Residues	17
Details	G_PROTEIN_RECEP_F1_1 G-protein coupled receptors family 1 signature. SSIfSLLAIAIDRYIaI

Chain	Residue	Details
A	SER90-ILE106

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	TRANSMEM: Helical; Name=1

Chain	Residue	Details
A	VAL8-TRP32

site_id	SWS_FT_FI2
Number of Residues	28
Details	TOPO_DOM: Cytoplasmic => ECO:0000269\|PubMed:18832607

Chain	Residue	Details
A	LEU33-ASN42
A	ASP101-ARG120

site_id	SWS_FT_FI3
Number of Residues	23
Details	TRANSMEM: Helical; Name=2

Chain	Residue	Details
A	TYR43-ILE66

site_id	SWS_FT_FI4
Number of Residues	46
Details	TOPO_DOM: Extracellular => ECO:0000269\|PubMed:18832607

Chain	Residue	Details
A	SER67-CYS77
A	ASN144-PRO173
A	CYS259-PRO266

site_id	SWS_FT_FI5
Number of Residues	22
Details	TRANSMEM: Helical; Name=3

Chain	Residue	Details
A	LEU78-ILE100

site_id	SWS_FT_FI6
Number of Residues	22
Details	TRANSMEM: Helical; Name=4

Chain	Residue	Details
A	ALA121-TRP143

site_id	SWS_FT_FI7
Number of Residues	24
Details	TRANSMEM: Helical; Name=5

Chain	Residue	Details
A	MET174-LEU198

site_id	SWS_FT_FI8
Number of Residues	23
Details	TRANSMEM: Helical; Name=6

Chain	Residue	Details
A	ALA235-PHE258

site_id	SWS_FT_FI9
Number of Residues	23
Details	TRANSMEM: Helical; Name=7

Chain	Residue	Details
A	LEU267-TYR290

site_id	SWS_FT_FI10
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269\|PubMed:21593763, ECO:0007744\|PDB:2YDO

Chain	Residue	Details
A	GLU169
A	ASN253
A	ALA277
A	HIS278

site_id	SWS_FT_FI11
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
A	ALA154

site_id	SWS_FT_FI12
Number of Residues	2
Details	BINDING: axial binding residue

Chain	Residue	Details
A	TRP1007
A	ILE1102

237423

PDB entries from 2025-06-11

PDB statistics

PDBj update info

Contact PDBj

numon