5OL2
The electron transferring flavoprotein/butyryl-CoA dehydrogenase complex from Clostridium difficile
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0009055 | molecular_function | electron transfer activity |
| A | 0033539 | biological_process | fatty acid beta-oxidation using acyl-CoA dehydrogenase |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0009055 | molecular_function | electron transfer activity |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0003995 | molecular_function | acyl-CoA dehydrogenase activity |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0016627 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors |
| C | 0016937 | molecular_function | short-chain fatty acyl-CoA dehydrogenase activity |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0009055 | molecular_function | electron transfer activity |
| D | 0033539 | biological_process | fatty acid beta-oxidation using acyl-CoA dehydrogenase |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| E | 0000166 | molecular_function | nucleotide binding |
| E | 0009055 | molecular_function | electron transfer activity |
| F | 0000166 | molecular_function | nucleotide binding |
| F | 0003995 | molecular_function | acyl-CoA dehydrogenase activity |
| F | 0016491 | molecular_function | oxidoreductase activity |
| F | 0016627 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors |
| F | 0016937 | molecular_function | short-chain fatty acyl-CoA dehydrogenase activity |
| F | 0046872 | molecular_function | metal ion binding |
| F | 0050660 | molecular_function | flavin adenine dinucleotide binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 28 |
| Details | binding site for residue FAD A 401 |
| Chain | Residue |
| A | GLY216 |
| A | GLN259 |
| A | THR260 |
| A | GLY261 |
| A | GLY273 |
| A | ILE274 |
| A | SER275 |
| A | GLY276 |
| A | ALA277 |
| A | GLN279 |
| A | HIS280 |
| A | ARG217 |
| A | ASN294 |
| A | LYS295 |
| A | GLY311 |
| A | ASP312 |
| A | VAL313 |
| C | THR343 |
| C | TYR346 |
| F | PRO127 |
| F | GLU198 |
| A | GLY218 |
| A | SER242 |
| A | ARG243 |
| A | ALA244 |
| A | GLN256 |
| A | VAL257 |
| A | GLY258 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue CA A 402 |
| Chain | Residue |
| A | GLU75 |
| A | ASP188 |
| site_id | AC3 |
| Number of Residues | 23 |
| Details | binding site for residue FAD B 300 |
| Chain | Residue |
| A | LEU116 |
| A | THR117 |
| A | ARG136 |
| A | ILE147 |
| B | CYS11 |
| B | ILE12 |
| B | LYS13 |
| B | ASP43 |
| B | MET66 |
| B | ALA97 |
| B | ASP98 |
| B | THR99 |
| B | THR102 |
| B | ALA120 |
| B | GLY121 |
| B | ALA124 |
| B | GLY127 |
| B | ASP128 |
| B | THR129 |
| B | ALA130 |
| B | GLN131 |
| B | VAL132 |
| B | THR227 |
| site_id | AC4 |
| Number of Residues | 23 |
| Details | binding site for residue FAD C 401 |
| Chain | Residue |
| C | PHE122 |
| C | LEU124 |
| C | THR125 |
| C | GLY130 |
| C | THR131 |
| C | PHE155 |
| C | ILE156 |
| C | THR157 |
| C | GLN278 |
| C | ILE357 |
| C | TYR361 |
| C | GLU362 |
| C | THR364 |
| C | GLU366 |
| C | COS402 |
| F | ARG267 |
| F | GLN269 |
| F | PHE270 |
| F | LEU274 |
| F | GLN335 |
| F | LEU336 |
| F | GLY338 |
| F | GLY339 |
| site_id | AC5 |
| Number of Residues | 11 |
| Details | binding site for residue COS C 402 |
| Chain | Residue |
| B | ASP24 |
| B | THR27 |
| C | THR131 |
| C | SER134 |
| C | PHE231 |
| C | MET235 |
| C | LEU238 |
| C | ARG242 |
| C | GLU362 |
| C | GLY363 |
| C | FAD401 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue CA C 403 |
| Chain | Residue |
| C | GLU29 |
| C | GLU33 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue CA D 402 |
| Chain | Residue |
| D | GLU75 |
| D | ASP188 |
| site_id | AC8 |
| Number of Residues | 25 |
| Details | binding site for residue FAD E 301 |
| Chain | Residue |
| E | MET66 |
| E | ALA97 |
| E | ASP98 |
| E | THR99 |
| E | THR102 |
| E | ALA120 |
| E | GLY121 |
| E | ARG122 |
| E | GLN123 |
| E | ALA124 |
| E | GLY127 |
| E | ASP128 |
| E | THR129 |
| E | ALA130 |
| E | GLN131 |
| E | VAL132 |
| E | THR227 |
| D | LEU116 |
| D | THR117 |
| D | ARG136 |
| D | ILE147 |
| E | CYS11 |
| E | ILE12 |
| E | LYS13 |
| E | ASP43 |
| site_id | AC9 |
| Number of Residues | 23 |
| Details | binding site for residue FAD F 401 |
| Chain | Residue |
| C | ARG267 |
| C | PHE270 |
| C | LEU274 |
| C | PHE277 |
| C | GLN335 |
| C | LEU336 |
| C | GLY338 |
| C | GLY339 |
| F | PHE122 |
| F | LEU124 |
| F | THR125 |
| F | GLY130 |
| F | THR131 |
| F | PHE155 |
| F | ILE156 |
| F | THR157 |
| F | GLN278 |
| F | ILE357 |
| F | TYR361 |
| F | GLU362 |
| F | THR364 |
| F | GLU366 |
| F | COS402 |
| site_id | AD1 |
| Number of Residues | 10 |
| Details | binding site for residue COS F 402 |
| Chain | Residue |
| F | THR125 |
| F | THR131 |
| F | MET235 |
| F | LEU238 |
| F | ARG242 |
| F | LYS276 |
| F | GLU362 |
| F | GLY363 |
| F | MET370 |
| F | FAD401 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue CA F 403 |
| Chain | Residue |
| F | GLU29 |
| F | GLU33 |
| F | ARG35 |
| site_id | AD3 |
| Number of Residues | 30 |
| Details | binding site for Di-peptide FAD D 401 and ASN D 294 |
| Chain | Residue |
| C | PRO127 |
| C | GLU198 |
| D | GLY216 |
| D | ARG217 |
| D | GLY218 |
| D | SER242 |
| D | ARG243 |
| D | ALA244 |
| D | GLN256 |
| D | VAL257 |
| D | GLY258 |
| D | GLN259 |
| D | THR260 |
| D | GLY261 |
| D | GLY273 |
| D | ILE274 |
| D | SER275 |
| D | GLY276 |
| D | ALA277 |
| D | GLN279 |
| D | HIS280 |
| D | ILE293 |
| D | LYS295 |
| D | ASN296 |
| D | ILE309 |
| D | VAL310 |
| D | GLY311 |
| D | VAL313 |
| F | THR343 |
| F | TYR346 |
| site_id | AD4 |
| Number of Residues | 32 |
| Details | binding site for Di-peptide FAD D 401 and HIS D 280 |
| Chain | Residue |
| C | PRO127 |
| C | GLU198 |
| D | GLY216 |
| D | ARG217 |
| D | GLY218 |
| D | SER242 |
| D | ARG243 |
| D | ALA244 |
| D | GLN256 |
| D | VAL257 |
| D | GLY258 |
| D | GLN259 |
| D | THR260 |
| D | GLY261 |
| D | TYR269 |
| D | GLY273 |
| D | ILE274 |
| D | SER275 |
| D | GLY276 |
| D | ALA277 |
| D | ILE278 |
| D | GLN279 |
| D | ILE281 |
| D | ALA282 |
| D | GLY283 |
| D | ASN294 |
| D | LYS295 |
| D | ASN296 |
| D | GLY311 |
| D | VAL313 |
| F | THR343 |
| F | TYR346 |
Functional Information from PROSITE/UniProt
| site_id | PS00072 |
| Number of Residues | 13 |
| Details | ACYL_COA_DH_1 Acyl-CoA dehydrogenases signature 1. GLTEpnAGTDasG |
| Chain | Residue | Details |
| C | GLY123-GLY135 |
| site_id | PS00073 |
| Number of Residues | 20 |
| Details | ACYL_COA_DH_2 Acyl-CoA dehydrogenases signature 2. QlHGGyGYtrDypveRmmrD |
| Chain | Residue | Details |
| C | GLN335-ASP354 |
| site_id | PS00696 |
| Number of Residues | 27 |
| Details | ETF_ALPHA Electron transfer flavoprotein alpha-subunit signature. LYIAcGISGaIQHiaGmedaefIvAIN |
| Chain | Residue | Details |
| A | LEU268-ASN294 |
