5OHF

Globin sensor domain of AfGcHK (FeIII form) in complex with cyanide, partially reduced

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0019825	molecular_function	oxygen binding
A	0020037	molecular_function	heme binding
B	0019825	molecular_function	oxygen binding
B	0020037	molecular_function	heme binding
C	0019825	molecular_function	oxygen binding
C	0020037	molecular_function	heme binding
D	0019825	molecular_function	oxygen binding
D	0020037	molecular_function	heme binding
E	0019825	molecular_function	oxygen binding
E	0020037	molecular_function	heme binding
F	0019825	molecular_function	oxygen binding
F	0020037	molecular_function	heme binding
G	0019825	molecular_function	oxygen binding
G	0020037	molecular_function	heme binding
H	0019825	molecular_function	oxygen binding
H	0020037	molecular_function	heme binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	binding site for residue HEM A 200

Chain	Residue
A	ILE48
A	MET153
A	CYN201
A	HOH305
A	HOH379
A	ALA54
A	ALA57
A	MET72
A	TRP75
A	HIS99
A	LEU104
A	MET109
A	MET113

---

site_id	AC2
Number of Residues	4
Details	binding site for residue CYN A 201

Chain	Residue
A	PHE44
A	TYR45
A	MET72
A	HEM200

---

site_id	AC3
Number of Residues	2
Details	binding site for residue CL A 202

Chain	Residue
A	ARG139
B	ARG139

---

site_id	AC4
Number of Residues	12
Details	binding site for residue HEM B 200

Chain	Residue
B	ILE48
B	ALA54
B	ALA57
B	MET72
B	TRP75
B	HIS99
B	ILE102
B	LEU104
B	MET109
B	MET113
B	MET153
B	CYN201

---

site_id	AC5
Number of Residues	4
Details	binding site for residue CYN B 201

Chain	Residue
B	TYR45
B	MET72
B	HEM200
B	HOH318

---

site_id	AC6
Number of Residues	11
Details	binding site for residue HEM C 200

Chain	Residue
C	ALA54
C	ALA57
C	MET72
C	TRP75
C	VAL98
C	HIS99
C	ILE102
C	LEU104
C	ALA112
C	MET113
C	CYN201

---

site_id	AC7
Number of Residues	5
Details	binding site for residue CYN C 201

Chain	Residue
C	TYR45
C	LEU68
C	MET72
C	HEM200
C	HOH312

---

site_id	AC8
Number of Residues	2
Details	binding site for residue CL C 202

Chain	Residue
C	ARG139
D	ARG139

---

site_id	AC9
Number of Residues	13
Details	binding site for residue HEM D 200

Chain	Residue
D	ALA54
D	ALA57
D	LEU68
D	MET72
D	TRP75
D	HIS99
D	ILE102
D	LEU104
D	ALA112
D	MET113
D	CYN201
D	HOH337
D	HOH354

---

site_id	AD1
Number of Residues	4
Details	binding site for residue CYN D 201

Chain	Residue
D	TYR45
D	MET72
D	HEM200
D	HOH313

---

site_id	AD2
Number of Residues	2
Details	binding site for residue CL D 202

Chain	Residue
D	ARG55
F	HOH411

---

site_id	AD3
Number of Residues	16
Details	binding site for residue HEM E 201

Chain	Residue
E	ALA54
E	GLN64
E	MET72
E	TRP75
E	VAL98
E	HIS99
E	ARG101
E	ILE102
E	LEU104
E	MET109
E	ALA112
E	MET113
E	CYN202
E	HOH340
E	HOH359
E	HOH380

---

site_id	AD4
Number of Residues	3
Details	binding site for residue CYN E 202

Chain	Residue
E	TYR45
E	MET72
E	HEM201

---

site_id	AD5
Number of Residues	2
Details	binding site for residue CL E 203

Chain	Residue
E	ARG139
F	ARG139

---

site_id	AD6
Number of Residues	5
Details	binding site for residue NA E 204

Chain	Residue
E	ARG55
E	LEU58
E	HOH402
E	HOH414
H	HOH318

---

site_id	AD7
Number of Residues	14
Details	binding site for residue HEM F 200

Chain	Residue
F	ALA54
F	GLN64
F	LEU68
F	MET72
F	TRP75
F	VAL98
F	HIS99
F	ARG101
F	ILE102
F	LEU104
F	MET109
F	MET113
F	CYN201
F	ILE48

---

site_id	AD8
Number of Residues	4
Details	binding site for residue CYN F 201

Chain	Residue
F	TYR45
F	LEU68
F	HEM200
F	HOH324

---

site_id	AD9
Number of Residues	2
Details	binding site for residue CL G 202

Chain	Residue
G	ARG139
H	ARG139

---

site_id	AE1
Number of Residues	17
Details	binding site for residue HEM H 200

Chain	Residue
E	HOH339
H	ILE48
H	ALA54
H	GLN64
H	LEU68
H	MET72
H	TRP75
H	VAL98
H	HIS99
H	LEU104
H	MET109
H	ALA112
H	MET113
H	CYN201
H	HOH318
H	HOH329
H	HOH333

---

site_id	AE2
Number of Residues	4
Details	binding site for residue CYN H 201

Chain	Residue
H	TYR45
H	MET72
H	HEM200
H	HOH349

---

site_id	AE3
Number of Residues	26
Details	binding site for residues HEM G 200 and CYN G 201

Chain	Residue
F	VAL59
G	PHE44
G	TYR45
G	ILE48
G	ALA54
G	ALA57
G	LEU58
G	GLN64
G	HIS67
G	LEU68
G	THR71
G	MET72
G	TRP75
G	ARG94
G	ILE95
G	VAL98
G	HIS99
G	ILE102
G	LEU104
G	MET109
G	ALA112
G	MET113
G	HIS116
G	MET153
G	HOH317
H	TYR15

---

site_id	AE4
Number of Residues	26
Details	binding site for residues HEM G 200 and CYN G 201

Chain	Residue
F	VAL59
G	PHE44
G	TYR45
G	ILE48
G	ALA54
G	ALA57
G	LEU58
G	GLN64
G	HIS67
G	LEU68
G	THR71
G	MET72
G	TRP75
G	ARG94
G	ILE95
G	VAL98
G	HIS99
G	ILE102
G	LEU104
G	MET109
G	ALA112
G	MET113
G	HIS116
G	MET153
G	HOH317
H	TYR15

---

site_id	AE5
Number of Residues	26
Details	binding site for residues HEM G 200 and CYN G 201

Chain	Residue
F	VAL59
G	PHE44
G	TYR45
G	ILE48
G	ALA54
G	ALA57
G	LEU58
G	GLN64
G	HIS67
G	LEU68
G	THR71
G	MET72
G	TRP75
G	ARG94
G	ILE95
G	VAL98
G	HIS99
G	ILE102
G	LEU104
G	MET109
G	ALA112
G	MET113
G	HIS116
G	MET153
G	HOH317
H	TYR15

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21852234","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	Binding site: {"description":"proximal binding residue","evidences":[{"source":"PubMed","id":"21852234","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---