5OES
The structure of a glutathione synthetase (StGSS1) from Solanum tuberosum in ADP and y-EC bound closed conformation.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0004363 | molecular_function | glutathione synthase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0006750 | biological_process | glutathione biosynthetic process |
| A | 0016874 | molecular_function | ligase activity |
| A | 0043295 | molecular_function | glutathione binding |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0004363 | molecular_function | glutathione synthase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0006750 | biological_process | glutathione biosynthetic process |
| B | 0016874 | molecular_function | ligase activity |
| B | 0043295 | molecular_function | glutathione binding |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0000287 | molecular_function | magnesium ion binding |
| C | 0004363 | molecular_function | glutathione synthase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005829 | cellular_component | cytosol |
| C | 0006750 | biological_process | glutathione biosynthetic process |
| C | 0016874 | molecular_function | ligase activity |
| C | 0043295 | molecular_function | glutathione binding |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0000287 | molecular_function | magnesium ion binding |
| D | 0004363 | molecular_function | glutathione synthase activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005829 | cellular_component | cytosol |
| D | 0006750 | biological_process | glutathione biosynthetic process |
| D | 0016874 | molecular_function | ligase activity |
| D | 0043295 | molecular_function | glutathione binding |
| D | 0046872 | molecular_function | metal ion binding |
| E | 0000166 | molecular_function | nucleotide binding |
| E | 0000287 | molecular_function | magnesium ion binding |
| E | 0004363 | molecular_function | glutathione synthase activity |
| E | 0005524 | molecular_function | ATP binding |
| E | 0005829 | cellular_component | cytosol |
| E | 0006750 | biological_process | glutathione biosynthetic process |
| E | 0016874 | molecular_function | ligase activity |
| E | 0043295 | molecular_function | glutathione binding |
| E | 0046872 | molecular_function | metal ion binding |
| F | 0000166 | molecular_function | nucleotide binding |
| F | 0000287 | molecular_function | magnesium ion binding |
| F | 0004363 | molecular_function | glutathione synthase activity |
| F | 0005524 | molecular_function | ATP binding |
| F | 0005829 | cellular_component | cytosol |
| F | 0006750 | biological_process | glutathione biosynthetic process |
| F | 0016874 | molecular_function | ligase activity |
| F | 0043295 | molecular_function | glutathione binding |
| F | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | binding site for residue ADP A 501 |
| Chain | Residue |
| A | MET141 |
| A | ARG410 |
| A | ILE411 |
| A | GLU434 |
| A | LYS461 |
| A | MG504 |
| A | ILE152 |
| A | GLU153 |
| A | LYS318 |
| A | LYS372 |
| A | ASN381 |
| A | TYR383 |
| A | MET408 |
| A | GLN409 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | binding site for residue 3GC A 502 |
| Chain | Residue |
| A | ARG137 |
| A | ASN155 |
| A | ILE157 |
| A | SER158 |
| A | SER160 |
| A | GLU225 |
| A | ASN227 |
| A | GLN231 |
| A | ARG279 |
| A | TYR282 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue MG A 503 |
| Chain | Residue |
| A | LEU154 |
| A | GLY316 |
| A | HOH666 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 504 |
| Chain | Residue |
| A | ASP139 |
| A | GLU153 |
| A | GLU434 |
| A | ARG459 |
| A | ADP501 |
| site_id | AC5 |
| Number of Residues | 11 |
| Details | binding site for residue ADP B 501 |
| Chain | Residue |
| B | MET141 |
| B | GLU153 |
| B | LYS372 |
| B | ASN381 |
| B | TYR383 |
| B | MET408 |
| B | GLN409 |
| B | ARG410 |
| B | ILE411 |
| B | GLU434 |
| B | LYS461 |
| site_id | AC6 |
| Number of Residues | 10 |
| Details | binding site for residue 3GC B 502 |
| Chain | Residue |
| B | ARG137 |
| B | ASN155 |
| B | ILE157 |
| B | SER158 |
| B | SER160 |
| B | GLU225 |
| B | ASN227 |
| B | GLN231 |
| B | ARG279 |
| B | TYR282 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue MG B 503 |
| Chain | Residue |
| B | LEU154 |
| B | GLY316 |
| B | HOH655 |
| site_id | AC8 |
| Number of Residues | 16 |
| Details | binding site for residue ADP C 501 |
| Chain | Residue |
| C | MET141 |
| C | ILE152 |
| C | GLU153 |
| C | LYS318 |
| C | VAL370 |
| C | LYS372 |
| C | ASN381 |
| C | TYR383 |
| C | MET408 |
| C | GLN409 |
| C | ARG410 |
| C | ILE411 |
| C | GLU434 |
| C | LYS461 |
| C | MG504 |
| C | HOH629 |
| site_id | AC9 |
| Number of Residues | 10 |
| Details | binding site for residue 3GC C 502 |
| Chain | Residue |
| C | ARG137 |
| C | ASN155 |
| C | ILE157 |
| C | SER158 |
| C | SER160 |
| C | GLU225 |
| C | ASN227 |
| C | GLN231 |
| C | ARG279 |
| C | TYR282 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue MG C 503 |
| Chain | Residue |
| C | LEU154 |
| C | GLY316 |
| C | HOH616 |
| C | HOH634 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue MG C 504 |
| Chain | Residue |
| C | ASP139 |
| C | GLU153 |
| C | GLU434 |
| C | ARG459 |
| C | ADP501 |
| site_id | AD3 |
| Number of Residues | 13 |
| Details | binding site for residue ADP D 501 |
| Chain | Residue |
| D | ARG410 |
| D | ILE411 |
| D | GLU434 |
| D | LYS461 |
| D | MG503 |
| D | MET141 |
| D | GLU153 |
| D | VAL370 |
| D | LYS372 |
| D | ASN381 |
| D | TYR383 |
| D | MET408 |
| D | GLN409 |
| site_id | AD4 |
| Number of Residues | 10 |
| Details | binding site for residue 3GC D 502 |
| Chain | Residue |
| D | ARG137 |
| D | ASN155 |
| D | ILE157 |
| D | SER158 |
| D | SER160 |
| D | GLU225 |
| D | ASN227 |
| D | GLN231 |
| D | ARG279 |
| D | TYR282 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue MG D 503 |
| Chain | Residue |
| D | ASP139 |
| D | GLU153 |
| D | GLU434 |
| D | ARG459 |
| D | ADP501 |
| site_id | AD6 |
| Number of Residues | 3 |
| Details | binding site for residue MG D 504 |
| Chain | Residue |
| D | LEU154 |
| D | GLY316 |
| D | HOH629 |
| site_id | AD7 |
| Number of Residues | 13 |
| Details | binding site for residue ADP E 501 |
| Chain | Residue |
| E | MET141 |
| E | GLU153 |
| E | LYS372 |
| E | GLU376 |
| E | ASN381 |
| E | TYR383 |
| E | MET408 |
| E | GLN409 |
| E | ARG410 |
| E | ILE411 |
| E | GLU434 |
| E | LYS461 |
| E | HOH632 |
| site_id | AD8 |
| Number of Residues | 10 |
| Details | binding site for residue 3GC E 502 |
| Chain | Residue |
| E | ARG137 |
| E | ASN155 |
| E | ILE157 |
| E | SER158 |
| E | SER160 |
| E | GLU225 |
| E | ASN227 |
| E | GLN231 |
| E | ARG279 |
| E | TYR282 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue MG E 503 |
| Chain | Residue |
| E | LEU154 |
| E | GLY316 |
| E | GLU376 |
| E | HOH651 |
| site_id | AE1 |
| Number of Residues | 4 |
| Details | binding site for residue MG E 504 |
| Chain | Residue |
| E | ASP139 |
| E | GLU153 |
| E | GLU434 |
| E | ARG459 |
| site_id | AE2 |
| Number of Residues | 13 |
| Details | binding site for residue ADP F 501 |
| Chain | Residue |
| F | MET141 |
| F | ILE152 |
| F | GLU153 |
| F | LYS318 |
| F | LYS372 |
| F | ASN381 |
| F | TYR383 |
| F | MET408 |
| F | GLN409 |
| F | ILE411 |
| F | GLU434 |
| F | LYS461 |
| F | HOH621 |
| site_id | AE3 |
| Number of Residues | 10 |
| Details | binding site for residue 3GC F 502 |
| Chain | Residue |
| F | ARG137 |
| F | ASN155 |
| F | ILE157 |
| F | SER158 |
| F | SER160 |
| F | GLU225 |
| F | ASN227 |
| F | GLN231 |
| F | ARG279 |
| F | TYR282 |
| site_id | AE4 |
| Number of Residues | 4 |
| Details | binding site for residue MG F 503 |
| Chain | Residue |
| F | LEU154 |
| F | GLY316 |
| F | GLN321 |
| F | HOH642 |
