5OAS

Crystal structure of malate synthase G from Pseudomonas aeruginosa in apo form.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0003824	molecular_function	catalytic activity
A	0004474	molecular_function	malate synthase activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006097	biological_process	glyoxylate cycle
A	0006099	biological_process	tricarboxylic acid cycle
A	0009436	biological_process	glyoxylate catabolic process
A	0016740	molecular_function	transferase activity
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue GOL A 801

Chain	Residue
A	VAL280
A	THR347
A	GLU358
A	HIS713
A	HOH1059
A	HOH1256
A	HOH1299

---

site_id	AC2
Number of Residues	3
Details	binding site for residue GOL A 802

Chain	Residue
A	LYS555
A	GLU87
A	PHE171

---

site_id	AC3
Number of Residues	11
Details	binding site for residue GOL A 803

Chain	Residue
A	GLU108
A	ARG134
A	HIS332
A	ARG334
A	SER335
A	LEU336
A	LYS384
A	ASN385
A	ARG387
A	MG821
A	HOH1210

---

site_id	AC4
Number of Residues	7
Details	binding site for residue GOL A 804

Chain	Residue
A	GLN61
A	HIS467
A	THR701
A	PRO704
A	ASN705
A	HOH970
A	HOH1039

---

site_id	AC5
Number of Residues	1
Details	binding site for residue EDO A 805

Chain	Residue
A	ARG111

---

site_id	AC6
Number of Residues	6
Details	binding site for residue EDO A 806

Chain	Residue
A	ASP33
A	THR37
A	THR322
A	GLU328
A	HOH986
A	HOH1271

---

site_id	AC7
Number of Residues	4
Details	binding site for residue EDO A 807

Chain	Residue
A	LEU377
A	ASN378
A	LEU420
A	EDO812

---

site_id	AC8
Number of Residues	9
Details	binding site for residue EDO A 808

Chain	Residue
A	GLU432
A	GLY457
A	PHE458
A	LEU459
A	ASP460
A	ALA633
A	MG820
A	HOH909
A	HOH969

---

site_id	AC9
Number of Residues	3
Details	binding site for residue EDO A 809

Chain	Residue
A	TYR139
A	ASP140
A	HOH1146

---

site_id	AD1
Number of Residues	4
Details	binding site for residue EDO A 810

Chain	Residue
A	LYS14
A	HIS332
A	ARG387
A	HOH944

---

site_id	AD2
Number of Residues	7
Details	binding site for residue EDO A 811

Chain	Residue
A	MET122
A	ASN123
A	ALA124
A	ARG125
A	ASN291
A	GLU302
A	HOH1459

---

site_id	AD3
Number of Residues	4
Details	binding site for residue EDO A 812

Chain	Residue
A	THR28
A	LEU418
A	GLY419
A	EDO807

---

site_id	AD4
Number of Residues	3
Details	binding site for residue EDO A 813

Chain	Residue
A	ALA324
A	ASP325
A	HOH973

---

site_id	AD5
Number of Residues	6
Details	binding site for residue EDO A 814

Chain	Residue
A	ASP281
A	ARG717
A	LYS720
A	ALA721
A	HOH904
A	HOH1386

---

site_id	AD6
Number of Residues	5
Details	binding site for residue EDO A 815

Chain	Residue
A	ASP284
A	ARG716
A	LYS720
A	HOH926
A	HOH927

---

site_id	AD7
Number of Residues	6
Details	binding site for residue EDO A 816

Chain	Residue
A	MET513
A	TRP514
A	ALA515
A	MET516
A	HOH906
A	HOH1153

---

site_id	AD8
Number of Residues	7
Details	binding site for residue EDO A 817

Chain	Residue
A	GLU94
A	VAL438
A	LEU440
A	LYS441
A	HOH962
A	HOH980
A	HOH1211

---

site_id	AD9
Number of Residues	7
Details	binding site for residue MG A 820

Chain	Residue
A	EDO808
A	GLU274
A	ARG340
A	PRO396
A	LYS397
A	GLU432
A	ASP460

---

site_id	AE1
Number of Residues	6
Details	binding site for residue MG A 821

Chain	Residue
A	ASP318
A	HIS332
A	GLY333
A	ARG334
A	ARG387
A	GOL803

---

site_id	AE2
Number of Residues	12
Details	binding site for residues EDO A 818 and EDO A 819

Chain	Residue
A	ALA-2
A	ARG-1
A	ALA-2
A	MET1
A	MET1
A	PRO26
A	PRO26
A	LYS297
A	LYS297
A	ASN380
A	ASN380
A	ALA721

---

site_id	AE3
Number of Residues	12
Details	binding site for residues EDO A 818 and EDO A 819

Chain	Residue
A	ALA-2
A	ARG-1
A	ALA-2
A	MET1
A	MET1
A	PRO26
A	PRO26
A	LYS297
A	LYS297
A	ASN380
A	ASN380
A	ALA721

---

site_id	AE4
Number of Residues	12
Details	binding site for residues EDO A 818 and EDO A 819

Chain	Residue
A	ALA-2
A	ARG-1
A	ALA-2
A	MET1
A	MET1
A	PRO26
A	PRO26
A	LYS297
A	LYS297
A	ASN380
A	ASN380
A	ALA721

---

site_id	AE5
Number of Residues	12
Details	binding site for residues EDO A 818 and EDO A 819

Chain	Residue
A	ALA-2
A	ARG-1
A	ALA-2
A	MET1
A	MET1
A	PRO26
A	PRO26
A	LYS297
A	LYS297
A	ASN380
A	ASN380
A	ALA721

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_00641","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"description":"Proton donor","evidences":[{"source":"HAMAP-Rule","id":"MF_00641","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	11
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00641","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"Cysteine sulfenic acid (-SOH)","evidences":[{"source":"HAMAP-Rule","id":"MF_00641","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---