5O96

Structure of the putative methyltransferase Lpg2936 from Legionella pneumophila in complex with the bound cofactor SAM

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0006364	biological_process	rRNA processing
A	0008168	molecular_function	methyltransferase activity
A	0032259	biological_process	methylation
A	0070042	molecular_function	rRNA (uridine-N3-)-methyltransferase activity
A	0070475	biological_process	rRNA base methylation
B	0005737	cellular_component	cytoplasm
B	0006364	biological_process	rRNA processing
B	0008168	molecular_function	methyltransferase activity
B	0032259	biological_process	methylation
B	0070042	molecular_function	rRNA (uridine-N3-)-methyltransferase activity
B	0070475	biological_process	rRNA base methylation
C	0005737	cellular_component	cytoplasm
C	0006364	biological_process	rRNA processing
C	0008168	molecular_function	methyltransferase activity
C	0032259	biological_process	methylation
C	0070042	molecular_function	rRNA (uridine-N3-)-methyltransferase activity
C	0070475	biological_process	rRNA base methylation
D	0005737	cellular_component	cytoplasm
D	0006364	biological_process	rRNA processing
D	0008168	molecular_function	methyltransferase activity
D	0032259	biological_process	methylation
D	0070042	molecular_function	rRNA (uridine-N3-)-methyltransferase activity
D	0070475	biological_process	rRNA base methylation
E	0005737	cellular_component	cytoplasm
E	0006364	biological_process	rRNA processing
E	0008168	molecular_function	methyltransferase activity
E	0032259	biological_process	methylation
E	0070042	molecular_function	rRNA (uridine-N3-)-methyltransferase activity
E	0070475	biological_process	rRNA base methylation
F	0005737	cellular_component	cytoplasm
F	0006364	biological_process	rRNA processing
F	0008168	molecular_function	methyltransferase activity
F	0032259	biological_process	methylation
F	0070042	molecular_function	rRNA (uridine-N3-)-methyltransferase activity
F	0070475	biological_process	rRNA base methylation
G	0005737	cellular_component	cytoplasm
G	0006364	biological_process	rRNA processing
G	0008168	molecular_function	methyltransferase activity
G	0032259	biological_process	methylation
G	0070042	molecular_function	rRNA (uridine-N3-)-methyltransferase activity
G	0070475	biological_process	rRNA base methylation
H	0005737	cellular_component	cytoplasm
H	0006364	biological_process	rRNA processing
H	0008168	molecular_function	methyltransferase activity
H	0032259	biological_process	methylation
H	0070042	molecular_function	rRNA (uridine-N3-)-methyltransferase activity
H	0070475	biological_process	rRNA base methylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	20
Details	binding site for residue SAM A 501

Chain	Residue
A	LEU173
A	GLY220
A	ARG222
A	VAL223
A	LEU224
A	ARG225
A	THR226
A	ALA229
A	HOH602
A	HOH623
A	HOH624
A	HIS174
A	HOH633
A	PRO175
A	GLY196
A	PRO197
A	GLU198
A	GLY200
A	SER218
A	LEU219

---

site_id	AC2
Number of Residues	17
Details	binding site for residue SAM B 501

Chain	Residue
B	LEU173
B	HIS174
B	PRO175
B	GLY196
B	PRO197
B	GLU198
B	GLY199
B	GLY200
B	LEU217
B	SER218
B	LEU219
B	GLY220
B	ARG222
B	LEU224
B	ALA229
B	HOH601
B	HOH663

---

site_id	AC3
Number of Residues	13
Details	binding site for residue SAM C 501

Chain	Residue
C	LEU173
C	HIS174
C	GLY196
C	PRO197
C	GLU198
C	GLY199
C	GLY200
C	LEU217
C	SER218
C	LEU219
C	GLY220
C	ARG222
C	LEU224

---

site_id	AC4
Number of Residues	16
Details	binding site for residue SAM D 501

Chain	Residue
C	ARG4
D	LEU173
D	HIS174
D	GLY196
D	PRO197
D	GLU198
D	GLY199
D	GLY200
D	LEU217
D	SER218
D	LEU219
D	GLY220
D	ARG222
D	VAL223
D	LEU224
D	ALA229

---

site_id	AC5
Number of Residues	17
Details	binding site for residue SAM E 501

Chain	Residue
E	LEU173
E	HIS174
E	PRO175
E	GLY196
E	PRO197
E	GLU198
E	PHE201
E	SER218
E	LEU219
E	GLY220
E	ARG222
E	VAL223
E	LEU224
E	ARG225
E	THR226
E	HOH615
F	GLN143

---

site_id	AC6
Number of Residues	13
Details	binding site for residue SAM F 501

Chain	Residue
E	GLN143
F	LEU173
F	HIS174
F	GLU198
F	LEU217
F	SER218
F	LEU219
F	GLY220
F	ARG222
F	VAL223
F	LEU224
F	ARG225
F	ALA229

---

site_id	AC7
Number of Residues	17
Details	binding site for residue SAM G 501

Chain	Residue
G	PRO197
G	GLU198
G	LEU217
G	SER218
G	LEU219
G	GLY220
G	ARG222
G	VAL223
G	LEU224
G	ARG225
G	THR226
G	GLU227
G	ALA229
G	HOH601
G	LEU173
G	HIS174
G	GLY196

---

site_id	AC8
Number of Residues	14
Details	binding site for residue SAM H 501

Chain	Residue
H	LEU173
H	HIS174
H	PRO175
H	GLY196
H	PRO197
H	GLU198
H	GLY200
H	LEU217
H	SER218
H	LEU219
H	GLY220
H	ARG222
H	LEU224
H	ALA229

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