5O6V

The cryo-EM structure of Tick-borne encephalitis virus complexed with Fab fragment of neutralizing antibody 19/1786

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0046983	molecular_function	protein dimerization activity
B	0046983	molecular_function	protein dimerization activity
C	0046983	molecular_function	protein dimerization activity
D	0019058	biological_process	viral life cycle
E	0019058	biological_process	viral life cycle
F	0019058	biological_process	viral life cycle

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH

Chain	Residue	Details
L	TYR192-HIS198

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1338
Details	TOPO_DOM: Extracellular => ECO:0000255

Chain	Residue	Details
A	SER1-SER447
B	SER1-SER447
C	SER1-SER447
E	VAL57-ALA75
F	LYS38-GLU55
F	VAL57-ALA75

---

site_id	SWS_FT_FI2
Number of Residues	60
Details	TRANSMEM: Helical => ECO:0000255

Chain	Residue	Details
A	ILE448-GLY468
B	ILE448-GLY468
C	ILE448-GLY468

---

site_id	SWS_FT_FI3
Number of Residues	18
Details	TOPO_DOM: Extracellular

Chain	Residue	Details
A	LEU469-THR475
B	LEU469-THR475
C	LEU469-THR475

---

site_id	SWS_FT_FI4
Number of Residues	60
Details	TRANSMEM: Helical => ECO:0000305

Chain	Residue	Details
A	MET476-ALA496
B	MET476-ALA496
C	MET476-ALA496

---

site_id	SWS_FT_FI5
Number of Residues	3
Details	SITE: Cleavage; by host signal peptidase => ECO:0000250|UniProtKB:P03314

Chain	Residue	Details
A	ALA496
B	ALA496
C	ALA496

---

site_id	SWS_FT_FI6
Number of Residues	3
Details	CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000250|UniProtKB:P14336, ECO:0000255|PROSITE-ProRule:PRU00498

Chain	Residue	Details
A	ASN154
B	ASN154
C	ASN154

---