5O6C
Crystal Structure of a threonine-selective RCR E3 ligase
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 4701 |
| Chain | Residue |
| A | CYS4390 |
| A | CYS4393 |
| A | HIS4413 |
| A | CYS4416 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 4702 |
| Chain | Residue |
| A | CYS4408 |
| A | HIS4410 |
| A | CYS4437 |
| A | CYS4440 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 4703 |
| Chain | Residue |
| A | CYS4509 |
| A | CYS4537 |
| A | CYS4540 |
| A | CYS4506 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 4704 |
| Chain | Residue |
| A | CYS4549 |
| A | HIS4552 |
| A | CYS4631 |
| A | CYS4634 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 4705 |
| Chain | Residue |
| A | CYS4561 |
| A | CYS4564 |
| A | CYS4579 |
| A | CYS4582 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 4706 |
| Chain | Residue |
| A | CYS4565 |
| A | CYS4600 |
| A | CYS4614 |
| A | HIS4620 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 51 |
| Details | ZN_FING: RING-type; atypical => ECO:0000255|PROSITE-ProRule:PRU00175 |
| Chain | Residue | Details |
| A | PRO4428-SER4479 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: ACT_SITE => ECO:0000269|PubMed:29643511 |
| Chain | Residue | Details |
| A | GLU4558 | |
| A | GLU4610 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 20 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:29643511, ECO:0007744|PDB:5O6C |
| Chain | Residue | Details |
| A | PRO4428 | |
| A | GLN4547 | |
| A | THR4575 | |
| A | PHE4578 | |
| A | GLN4587 | |
| A | THR4590 | |
| A | HIS4599 | |
| A | ALA4602 | |
| A | GLY4603 | |
| A | HIS4617 | |
| A | HIS4620 | |
| A | THR4431 | |
| A | HIS4638 | |
| A | HIS4446 | |
| A | VAL4448 | |
| A | ASP4451 | |
| A | ASP4454 | |
| A | GLY4475 | |
| A | LYS4478 | |
| A | SER4544 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | SITE: Important for catalysis => ECO:0000269|PubMed:29643511 |
| Chain | Residue | Details |
| A | GLY4611 | |
| A | LEU4616 | |
| A | GLY4624 |
