5O5X

Crystal structure of Thermococcus litoralis ADP-dependent glucokinase (GK)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005975	biological_process	carbohydrate metabolic process
A	0016773	molecular_function	phosphotransferase activity, alcohol group as acceptor
B	0005975	biological_process	carbohydrate metabolic process
B	0016773	molecular_function	phosphotransferase activity, alcohol group as acceptor

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue SO4 A 501

Chain	Residue
A	LYS374
A	ILE375
A	VAL376
A	ALA419

---

site_id	AC2
Number of Residues	3
Details	binding site for residue SO4 A 502

Chain	Residue
A	GLU247
A	ARG287
B	TYR158

---

site_id	AC3
Number of Residues	4
Details	binding site for residue SO4 A 503

Chain	Residue
A	GLU58
A	HOH679
A	LYS54
A	ARG55

---

site_id	AC4
Number of Residues	5
Details	binding site for residue GOL A 504

Chain	Residue
A	ASN40
A	ASP42
A	GLU96
A	HIS184
A	HOH623

---

site_id	AC5
Number of Residues	4
Details	binding site for residue GOL A 505

Chain	Residue
A	ARG109
A	GLY112
A	TRP113
A	HOH684

---

site_id	AC6
Number of Residues	3
Details	binding site for residue GOL A 506

Chain	Residue
A	LYS13
A	ARG14
B	PHE331

---

site_id	AC7
Number of Residues	1
Details	binding site for residue GOL A 507

Chain	Residue
A	ASN338

---

site_id	AC8
Number of Residues	8
Details	binding site for residue GOL A 508

Chain	Residue
A	GLU279
A	ALA281
A	LEU304
A	ASN305
A	GLU308
A	HIS352
A	GLY386
A	ASP387

---

site_id	AC9
Number of Residues	5
Details	binding site for residue SO4 B 501

Chain	Residue
B	GLU279
B	GLY303
B	LEU304
B	GLU308
B	HIS352

---

site_id	AD1
Number of Residues	5
Details	binding site for residue SO4 B 502

Chain	Residue
B	LYS374
B	ILE375
B	VAL376
B	ALA416
B	ALA419

---

site_id	AD2
Number of Residues	3
Details	binding site for residue SO4 B 503

Chain	Residue
B	ASP212
B	TYR213
B	ARG216

---

site_id	AD3
Number of Residues	6
Details	binding site for residue GOL B 504

Chain	Residue
A	PRO437
A	GLU440
B	ASN273
B	LYS275
B	GLU347
B	GOL507

---

site_id	AD4
Number of Residues	2
Details	binding site for residue GOL B 505

Chain	Residue
B	GLY112
B	TRP113

---

site_id	AD5
Number of Residues	6
Details	binding site for residue GOL B 506

Chain	Residue
B	ASP42
B	GLU96
B	GLY119
B	GLY120
B	ILE124
B	HIS184

---

site_id	AD6
Number of Residues	4
Details	binding site for residue GOL B 507

Chain	Residue
A	ARG441
B	GLU397
B	PHE398
B	GOL504

---

site_id	AD7
Number of Residues	6
Details	binding site for residue GOL B 508

Chain	Residue
A	TYR354
B	MET341
B	ASP342
B	GLY345
B	GLN362
B	ARG366

---

site_id	AD8
Number of Residues	2
Details	binding site for residue GOL B 509

Chain	Residue
B	LEU368
B	GLU446

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00809","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"23818958","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4B8S","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00809","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"23818958","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4B8S","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00809","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11286887","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23818958","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1GC5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4B8S","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---