5O3I
Human Brd2(BD2) mutant in complex with AL-tBu
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | binding site for residue 9HN A 501 |
| Chain | Residue |
| A | LYS345 |
| A | TRP370 |
| A | PRO371 |
| A | TYR428 |
| A | ASN429 |
| A | HIS433 |
| A | MET438 |
| A | HOH601 |
| A | HOH623 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 502 |
| Chain | Residue |
| A | ARG419 |
| A | ARG419 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | binding site for residue DQW A 503 |
| Chain | Residue |
| A | TYR426 |
| A | TYR426 |
| A | ARG440 |
| A | ARG440 |
| A | GLN443 |
| A | ASP444 |
| A | ASP444 |
| A | GLU447 |
| A | HOH622 |
Functional Information from PROSITE/UniProt
| site_id | PS00633 |
| Number of Residues | 60 |
| Details | BROMODOMAIN_1 Bromodomain signature. AwpFykpvDasalgvhDYHdiIkhpMdlstVkrkmenrd..Yrdaqefaadvrl.MfsNCykY |
| Chain | Residue | Details |
| A | ALA369-TYR428 |
