5O0S

Crystal structure of txGH116 (beta-glucosidase from Thermoanaerobacterium xylolyticum) in complex with unreacted beta Cyclophellitol Cyclosulfate probe ME711

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004348	molecular_function	glucosylceramidase activity
A	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
A	0005975	biological_process	carbohydrate metabolic process
A	0006680	biological_process	glucosylceramide catabolic process
A	0008422	molecular_function	beta-glucosidase activity
A	0016020	cellular_component	membrane
A	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue EDO A 901

Chain	Residue
A	THR45
A	ILE46
A	GLU50
A	TYR764
A	LYS766
A	HOH1108

---

site_id	AC2
Number of Residues	8
Details	binding site for residue EDO A 902

Chain	Residue
A	LYS366
A	SER368
A	PHE369
A	HOH1368
A	HOH1398
A	GLN225
A	LYS235
A	GLU264

---

site_id	AC3
Number of Residues	6
Details	binding site for residue EDO A 903

Chain	Residue
A	VAL124
A	GLN126
A	LYS142
A	PRO146
A	ASN165
A	ASP167

---

site_id	AC4
Number of Residues	4
Details	binding site for residue EDO A 904

Chain	Residue
A	GLY362
A	LYS363
A	ASN364
A	HOH1175

---

site_id	AC5
Number of Residues	6
Details	binding site for residue EDO A 905

Chain	Residue
A	PHE443
A	ASP444
A	TYR513
A	EDO906
A	HOH1046
A	HOH1365

---

site_id	AC6
Number of Residues	7
Details	binding site for residue EDO A 906

Chain	Residue
A	LYS312
A	ASP444
A	ASN446
A	TYR447
A	EDO905
A	HOH1101
A	HOH1167

---

site_id	AC7
Number of Residues	10
Details	binding site for residue EDO A 907

Chain	Residue
A	MET218
A	ILE219
A	GLY220
A	PHE221
A	PHE222
A	TRP261
A	TYR265
A	LEU342
A	HOH1001
A	HOH1002

---

site_id	AC8
Number of Residues	5
Details	binding site for residue EDO A 908

Chain	Residue
A	LYS644
A	GLU645
A	TRP647
A	ASN648
A	ASN653

---

site_id	AC9
Number of Residues	8
Details	binding site for residue EDO A 909

Chain	Residue
A	LEU96
A	GLU97
A	ILE98
A	GLU260
A	MET345
A	LYS346
A	LYS355
A	HOH1138

---

site_id	AD1
Number of Residues	7
Details	binding site for residue CA A 910

Chain	Residue
A	ASP575
A	ASP577
A	ASP579
A	ILE581
A	ASP583
A	HOH1012
A	HOH1085

---

site_id	AD2
Number of Residues	13
Details	binding site for residue 9FQ A 911

Chain	Residue
A	GLU441
A	TYR445
A	ASP452
A	HIS507
A	TYR523
A	TRP531
A	THR591
A	ASP593
A	TRP732
A	GLU777
A	ARG786
A	TYR790
A	ARG792

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