5O0C
Crystal structure of Phosphopantetheine adenylyltransferase from Mycobacterium abcessus in complex with 3-(3-methyl-1H-indol-1-yl)propanoic acid (Fragment 3)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004595 | molecular_function | pantetheine-phosphate adenylyltransferase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0015937 | biological_process | coenzyme A biosynthetic process |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004595 | molecular_function | pantetheine-phosphate adenylyltransferase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0015937 | biological_process | coenzyme A biosynthetic process |
| B | 0016779 | molecular_function | nucleotidyltransferase activity |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0004595 | molecular_function | pantetheine-phosphate adenylyltransferase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0009058 | biological_process | biosynthetic process |
| C | 0015937 | biological_process | coenzyme A biosynthetic process |
| C | 0016779 | molecular_function | nucleotidyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue 9F8 A 201 |
| Chain | Residue |
| A | PRO7 |
| A | HOH303 |
| A | GLY8 |
| A | SER9 |
| A | PHE10 |
| A | HIS17 |
| A | VAL20 |
| A | LYS87 |
| A | GLY88 |
| A | THR118 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue 9F8 B 201 |
| Chain | Residue |
| B | PRO7 |
| B | GLY8 |
| B | SER9 |
| B | PHE10 |
| B | HIS17 |
| B | VAL20 |
| B | GLY88 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | binding site for residue 9F8 C 201 |
| Chain | Residue |
| C | PRO7 |
| C | GLY8 |
| C | SER9 |
| C | HIS17 |
| C | VAL20 |
| C | LYS87 |
| C | GLY88 |
| C | THR118 |
| C | HOH366 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 24 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00151 |
| Chain | Residue | Details |
| A | SER9 | |
| B | HIS17 | |
| B | LYS41 | |
| B | LEU73 | |
| B | LYS87 | |
| B | GLY88 | |
| B | GLU98 | |
| B | TYR122 | |
| C | SER9 | |
| C | HIS17 | |
| C | LYS41 | |
| A | HIS17 | |
| C | LEU73 | |
| C | LYS87 | |
| C | GLY88 | |
| C | GLU98 | |
| C | TYR122 | |
| A | LYS41 | |
| A | LEU73 | |
| A | LYS87 | |
| A | GLY88 | |
| A | GLU98 | |
| A | TYR122 | |
| B | SER9 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | SITE: Transition state stabilizer => ECO:0000255|HAMAP-Rule:MF_00151 |
| Chain | Residue | Details |
| A | HIS17 | |
| B | HIS17 | |
| C | HIS17 |
