5O0C

Crystal structure of Phosphopantetheine adenylyltransferase from Mycobacterium abcessus in complex with 3-(3-methyl-1H-indol-1-yl)propanoic acid (Fragment 3)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004595	molecular_function	pantetheine-phosphate adenylyltransferase activity
A	0005737	cellular_component	cytoplasm
A	0009058	biological_process	biosynthetic process
A	0015937	biological_process	coenzyme A biosynthetic process
B	0003824	molecular_function	catalytic activity
B	0004595	molecular_function	pantetheine-phosphate adenylyltransferase activity
B	0005737	cellular_component	cytoplasm
B	0009058	biological_process	biosynthetic process
B	0015937	biological_process	coenzyme A biosynthetic process
C	0003824	molecular_function	catalytic activity
C	0004595	molecular_function	pantetheine-phosphate adenylyltransferase activity
C	0005737	cellular_component	cytoplasm
C	0009058	biological_process	biosynthetic process
C	0015937	biological_process	coenzyme A biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	binding site for residue 9F8 A 201

Chain	Residue
A	PRO7
A	HOH303
A	GLY8
A	SER9
A	PHE10
A	HIS17
A	VAL20
A	LYS87
A	GLY88
A	THR118

---

site_id	AC2
Number of Residues	7
Details	binding site for residue 9F8 B 201

Chain	Residue
B	PRO7
B	GLY8
B	SER9
B	PHE10
B	HIS17
B	VAL20
B	GLY88

---

site_id	AC3
Number of Residues	9
Details	binding site for residue 9F8 C 201

Chain	Residue
C	PRO7
C	GLY8
C	SER9
C	HIS17
C	VAL20
C	LYS87
C	GLY88
C	THR118
C	HOH366

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	43
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00151","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	Site: {"description":"Transition state stabilizer","evidences":[{"source":"HAMAP-Rule","id":"MF_00151","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---