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5NZT

The structure of the COPI coat linkage I

Functional Information from GO Data
ChainGOidnamespacecontents
A0000139cellular_componentGolgi membrane
A0003729molecular_functionmRNA binding
A0005179molecular_functionhormone activity
A0005198molecular_functionstructural molecule activity
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0005737cellular_componentcytoplasm
A0005794cellular_componentGolgi apparatus
A0006886biological_processintracellular protein transport
A0006888biological_processendoplasmic reticulum to Golgi vesicle-mediated transport
A0006890biological_processretrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
A0006891biological_processintra-Golgi vesicle-mediated transport
A0007165biological_processsignal transduction
A0015031biological_processprotein transport
A0016020cellular_componentmembrane
A0016192biological_processvesicle-mediated transport
A0030117cellular_componentmembrane coat
A0030126cellular_componentCOPI vesicle coat
A0030137cellular_componentCOPI-coated vesicle
A0030157biological_processpancreatic juice secretion
A0030424cellular_componentaxon
A0030426cellular_componentgrowth cone
A0030663cellular_componentCOPI-coated vesicle membrane
A0031410cellular_componentcytoplasmic vesicle
A0043025cellular_componentneuronal cell body
A0099612biological_processprotein localization to axon
A1902463biological_processprotein localization to cell leading edge
B0000139cellular_componentGolgi membrane
B0005198molecular_functionstructural molecule activity
B0005737cellular_componentcytoplasm
B0005793cellular_componentendoplasmic reticulum-Golgi intermediate compartment
B0005794cellular_componentGolgi apparatus
B0005798cellular_componentGolgi-associated vesicle
B0005829cellular_componentcytosol
B0005886cellular_componentplasma membrane
B0006886biological_processintracellular protein transport
B0006888biological_processendoplasmic reticulum to Golgi vesicle-mediated transport
B0006891biological_processintra-Golgi vesicle-mediated transport
B0015031biological_processprotein transport
B0016192biological_processvesicle-mediated transport
B0030117cellular_componentmembrane coat
B0030126cellular_componentCOPI vesicle coat
B0030137cellular_componentCOPI-coated vesicle
B0030663cellular_componentCOPI-coated vesicle membrane
B0031410cellular_componentcytoplasmic vesicle
B0043231cellular_componentintracellular membrane-bounded organelle
C0000139cellular_componentGolgi membrane
C0005080molecular_functionprotein kinase C binding
C0005198molecular_functionstructural molecule activity
C0005737cellular_componentcytoplasm
C0005794cellular_componentGolgi apparatus
C0005829cellular_componentcytosol
C0006886biological_processintracellular protein transport
C0006888biological_processendoplasmic reticulum to Golgi vesicle-mediated transport
C0006890biological_processretrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
C0006891biological_processintra-Golgi vesicle-mediated transport
C0015031biological_processprotein transport
C0016020cellular_componentmembrane
C0016192biological_processvesicle-mediated transport
C0030117cellular_componentmembrane coat
C0030126cellular_componentCOPI vesicle coat
C0030663cellular_componentCOPI-coated vesicle membrane
C0031410cellular_componentcytoplasmic vesicle
D0000139cellular_componentGolgi membrane
D0005737cellular_componentcytoplasm
D0005783cellular_componentendoplasmic reticulum
D0005794cellular_componentGolgi apparatus
D0006888biological_processendoplasmic reticulum to Golgi vesicle-mediated transport
D0006890biological_processretrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
D0008344biological_processadult locomotory behavior
D0015031biological_processprotein transport
D0016020cellular_componentmembrane
D0016192biological_processvesicle-mediated transport
D0021691biological_processcerebellar Purkinje cell layer maturation
D0030126cellular_componentCOPI vesicle coat
D0030137cellular_componentCOPI-coated vesicle
D0030663cellular_componentCOPI-coated vesicle membrane
D0031410cellular_componentcytoplasmic vesicle
D0043473biological_processpigmentation
D0048193biological_processGolgi vesicle transport
D0051645biological_processGolgi localization
D0051649biological_processestablishment of localization in cell
E0000139cellular_componentGolgi membrane
E0005198molecular_functionstructural molecule activity
E0005515molecular_functionprotein binding
E0005654cellular_componentnucleoplasm
E0005737cellular_componentcytoplasm
E0005794cellular_componentGolgi apparatus
E0006888biological_processendoplasmic reticulum to Golgi vesicle-mediated transport
E0006890biological_processretrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
E0006891biological_processintra-Golgi vesicle-mediated transport
E0015031biological_processprotein transport
E0016020cellular_componentmembrane
E0016192biological_processvesicle-mediated transport
E0030126cellular_componentCOPI vesicle coat
E0030137cellular_componentCOPI-coated vesicle
E0030663cellular_componentCOPI-coated vesicle membrane
E0031410cellular_componentcytoplasmic vesicle
E0099612biological_processprotein localization to axon
F0003924molecular_functionGTPase activity
F0005515molecular_functionprotein binding
F0005525molecular_functionGTP binding
F0005794cellular_componentGolgi apparatus
F0005829cellular_componentcytosol
F0005886cellular_componentplasma membrane
F0006886biological_processintracellular protein transport
F0006888biological_processendoplasmic reticulum to Golgi vesicle-mediated transport
F0006893biological_processGolgi to plasma membrane transport
F0010636biological_processpositive regulation of mitochondrial fusion
F0015031biological_processprotein transport
F0016192biological_processvesicle-mediated transport
F0016236biological_processmacroautophagy
F0016787molecular_functionhydrolase activity
F0019217biological_processregulation of fatty acid metabolic process
F0044232cellular_componentorganelle membrane contact site
F0048193biological_processGolgi vesicle transport
F0090141biological_processpositive regulation of mitochondrial fission
F1903292biological_processprotein localization to Golgi membrane
F1903358biological_processregulation of Golgi organization
G0000139cellular_componentGolgi membrane
G0005198molecular_functionstructural molecule activity
G0005737cellular_componentcytoplasm
G0005783cellular_componentendoplasmic reticulum
G0005793cellular_componentendoplasmic reticulum-Golgi intermediate compartment
G0005794cellular_componentGolgi apparatus
G0005829cellular_componentcytosol
G0006886biological_processintracellular protein transport
G0006888biological_processendoplasmic reticulum to Golgi vesicle-mediated transport
G0006891biological_processintra-Golgi vesicle-mediated transport
G0009306biological_processprotein secretion
G0015031biological_processprotein transport
G0016020cellular_componentmembrane
G0016192biological_processvesicle-mediated transport
G0030117cellular_componentmembrane coat
G0030126cellular_componentCOPI vesicle coat
G0030663cellular_componentCOPI-coated vesicle membrane
G0031410cellular_componentcytoplasmic vesicle
G0051683biological_processestablishment of Golgi localization
G0072384biological_processorganelle transport along microtubule
H0000139cellular_componentGolgi membrane
H0005080molecular_functionprotein kinase C binding
H0005198molecular_functionstructural molecule activity
H0005737cellular_componentcytoplasm
H0005794cellular_componentGolgi apparatus
H0005829cellular_componentcytosol
H0006886biological_processintracellular protein transport
H0006888biological_processendoplasmic reticulum to Golgi vesicle-mediated transport
H0006890biological_processretrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
H0006891biological_processintra-Golgi vesicle-mediated transport
H0015031biological_processprotein transport
H0016020cellular_componentmembrane
H0016192biological_processvesicle-mediated transport
H0030117cellular_componentmembrane coat
H0030126cellular_componentCOPI vesicle coat
H0030663cellular_componentCOPI-coated vesicle membrane
H0031410cellular_componentcytoplasmic vesicle
I0000139cellular_componentGolgi membrane
I0005737cellular_componentcytoplasm
I0005783cellular_componentendoplasmic reticulum
I0005794cellular_componentGolgi apparatus
I0006888biological_processendoplasmic reticulum to Golgi vesicle-mediated transport
I0006890biological_processretrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
I0008344biological_processadult locomotory behavior
I0015031biological_processprotein transport
I0016020cellular_componentmembrane
I0016192biological_processvesicle-mediated transport
I0021691biological_processcerebellar Purkinje cell layer maturation
I0030126cellular_componentCOPI vesicle coat
I0030137cellular_componentCOPI-coated vesicle
I0030663cellular_componentCOPI-coated vesicle membrane
I0031410cellular_componentcytoplasmic vesicle
I0043473biological_processpigmentation
I0048193biological_processGolgi vesicle transport
I0051645biological_processGolgi localization
I0051649biological_processestablishment of localization in cell
J0003924molecular_functionGTPase activity
J0005515molecular_functionprotein binding
J0005525molecular_functionGTP binding
J0005794cellular_componentGolgi apparatus
J0005829cellular_componentcytosol
J0005886cellular_componentplasma membrane
J0006886biological_processintracellular protein transport
J0006888biological_processendoplasmic reticulum to Golgi vesicle-mediated transport
J0006893biological_processGolgi to plasma membrane transport
J0010636biological_processpositive regulation of mitochondrial fusion
J0015031biological_processprotein transport
J0016192biological_processvesicle-mediated transport
J0016236biological_processmacroautophagy
J0016787molecular_functionhydrolase activity
J0019217biological_processregulation of fatty acid metabolic process
J0044232cellular_componentorganelle membrane contact site
J0048193biological_processGolgi vesicle transport
J0090141biological_processpositive regulation of mitochondrial fission
J1903292biological_processprotein localization to Golgi membrane
J1903358biological_processregulation of Golgi organization
K0000139cellular_componentGolgi membrane
K0005198molecular_functionstructural molecule activity
K0005737cellular_componentcytoplasm
K0005783cellular_componentendoplasmic reticulum
K0005793cellular_componentendoplasmic reticulum-Golgi intermediate compartment
K0005794cellular_componentGolgi apparatus
K0005829cellular_componentcytosol
K0006886biological_processintracellular protein transport
K0006888biological_processendoplasmic reticulum to Golgi vesicle-mediated transport
K0006891biological_processintra-Golgi vesicle-mediated transport
K0009306biological_processprotein secretion
K0015031biological_processprotein transport
K0016020cellular_componentmembrane
K0016192biological_processvesicle-mediated transport
K0030117cellular_componentmembrane coat
K0030126cellular_componentCOPI vesicle coat
K0030663cellular_componentCOPI-coated vesicle membrane
K0031410cellular_componentcytoplasmic vesicle
K0051683biological_processestablishment of Golgi localization
K0072384biological_processorganelle transport along microtubule
L0000139cellular_componentGolgi membrane
L0003674molecular_functionmolecular_function
L0005737cellular_componentcytoplasm
L0005794cellular_componentGolgi apparatus
L0006886biological_processintracellular protein transport
L0006890biological_processretrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
L0006891biological_processintra-Golgi vesicle-mediated transport
L0015031biological_processprotein transport
L0016020cellular_componentmembrane
L0016192biological_processvesicle-mediated transport
L0030117cellular_componentmembrane coat
L0030126cellular_componentCOPI vesicle coat
L0030663cellular_componentCOPI-coated vesicle membrane
L0031410cellular_componentcytoplasmic vesicle
M0003924molecular_functionGTPase activity
M0005515molecular_functionprotein binding
M0005525molecular_functionGTP binding
M0005794cellular_componentGolgi apparatus
M0005829cellular_componentcytosol
M0005886cellular_componentplasma membrane
M0006886biological_processintracellular protein transport
M0006888biological_processendoplasmic reticulum to Golgi vesicle-mediated transport
M0006893biological_processGolgi to plasma membrane transport
M0010636biological_processpositive regulation of mitochondrial fusion
M0015031biological_processprotein transport
M0016192biological_processvesicle-mediated transport
M0016236biological_processmacroautophagy
M0016787molecular_functionhydrolase activity
M0019217biological_processregulation of fatty acid metabolic process
M0044232cellular_componentorganelle membrane contact site
M0048193biological_processGolgi vesicle transport
M0090141biological_processpositive regulation of mitochondrial fission
M1903292biological_processprotein localization to Golgi membrane
M1903358biological_processregulation of Golgi organization
N0000139cellular_componentGolgi membrane
N0005198molecular_functionstructural molecule activity
N0005737cellular_componentcytoplasm
N0005793cellular_componentendoplasmic reticulum-Golgi intermediate compartment
N0005794cellular_componentGolgi apparatus
N0005798cellular_componentGolgi-associated vesicle
N0005829cellular_componentcytosol
N0005886cellular_componentplasma membrane
N0006886biological_processintracellular protein transport
N0006888biological_processendoplasmic reticulum to Golgi vesicle-mediated transport
N0006891biological_processintra-Golgi vesicle-mediated transport
N0015031biological_processprotein transport
N0016192biological_processvesicle-mediated transport
N0030117cellular_componentmembrane coat
N0030126cellular_componentCOPI vesicle coat
N0030137cellular_componentCOPI-coated vesicle
N0030663cellular_componentCOPI-coated vesicle membrane
N0031410cellular_componentcytoplasmic vesicle
N0043231cellular_componentintracellular membrane-bounded organelle
R0003924molecular_functionGTPase activity
R0005515molecular_functionprotein binding
R0005525molecular_functionGTP binding
R0005794cellular_componentGolgi apparatus
R0005829cellular_componentcytosol
R0005886cellular_componentplasma membrane
R0006886biological_processintracellular protein transport
R0006888biological_processendoplasmic reticulum to Golgi vesicle-mediated transport
R0006893biological_processGolgi to plasma membrane transport
R0010636biological_processpositive regulation of mitochondrial fusion
R0015031biological_processprotein transport
R0016192biological_processvesicle-mediated transport
R0016236biological_processmacroautophagy
R0016787molecular_functionhydrolase activity
R0019217biological_processregulation of fatty acid metabolic process
R0044232cellular_componentorganelle membrane contact site
R0048193biological_processGolgi vesicle transport
R0090141biological_processpositive regulation of mitochondrial fission
R1903292biological_processprotein localization to Golgi membrane
R1903358biological_processregulation of Golgi organization
Z0000139cellular_componentGolgi membrane
Z0003674molecular_functionmolecular_function
Z0005737cellular_componentcytoplasm
Z0005794cellular_componentGolgi apparatus
Z0006886biological_processintracellular protein transport
Z0006890biological_processretrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
Z0006891biological_processintra-Golgi vesicle-mediated transport
Z0015031biological_processprotein transport
Z0016020cellular_componentmembrane
Z0016192biological_processvesicle-mediated transport
Z0030117cellular_componentmembrane coat
Z0030126cellular_componentCOPI vesicle coat
Z0030663cellular_componentCOPI-coated vesicle membrane
Z0031410cellular_componentcytoplasmic vesicle
Functional Information from PROSITE/UniProt
site_idPS00678
Number of Residues15
DetailsWD_REPEATS_1 Trp-Asp (WD) repeats signature. VVSAslDqTVRVWDI
ChainResidueDetails
AVAL150-ILE164

site_idPS00989
Number of Residues11
DetailsCLAT_ADAPTOR_S Clathrin adaptor complexes small chain signature. VVYKssidLYF
ChainResidueDetails
ZVAL67-PHE77

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsMOD_RES: N-acetylmethionine => ECO:0000250|UniProtKB:P61923
ChainResidueDetails
ZMET1
RALA160
MLEU25
MTHR48
MGLY70
MASN126
MALA160
JLEU25
JTHR48
JGLY70
JASN126
LMET1
JALA160
FGLY70
FASN126
FALA160
RLEU25
RTHR48
RGLY70
RASN126

site_idSWS_FT_FI2
Number of Residues4
DetailsLIPID: N-myristoyl glycine => ECO:0000269|PubMed:19141284, ECO:0000269|PubMed:20601958
ChainResidueDetails
FGLY2
RGLY2
MGLY2
JGLY2

site_idSWS_FT_FI3
Number of Residues8
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0007744|PubMed:22106047
ChainResidueDetails
FLYS127
DLYS351
RLYS127
ILYS351
MLYS127
JLYS127

site_idSWS_FT_FI4
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P53621
ChainResidueDetails
ASER1193

222624

PDB entries from 2024-07-17

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