5NZL

Crystal structure of UDP-glucose pyrophosphorylase from Leishmania major in complex with resveratrol

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003983	molecular_function	UTP:glucose-1-phosphate uridylyltransferase activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005977	biological_process	glycogen metabolic process
A	0006011	biological_process	UDP-alpha-D-glucose metabolic process
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0031981	cellular_component	nuclear lumen
A	0070569	molecular_function	uridylyltransferase activity
A	0097014	cellular_component	ciliary plasm

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue STL A 601

Chain	Residue
A	CYS247
A	ARG248
A	THR250
A	VAL371
A	PRO372
A	ARG373
A	SER374
A	EDO604

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site_id	AC2
Number of Residues	2
Details	binding site for residue EDO A 602

Chain	Residue
A	GLU180
A	ALA177

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site_id	AC3
Number of Residues	2
Details	binding site for residue EDO A 603

Chain	Residue
A	MET161
A	SER201

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site_id	AC4
Number of Residues	5
Details	binding site for residue EDO A 604

Chain	Residue
A	LEU61
A	ASP62
A	VAL370
A	PRO372
A	STL601

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site_id	AC5
Number of Residues	5
Details	binding site for residue EDO A 605

Chain	Residue
A	LYS80
A	GLN113
A	ALA225
A	THR226
A	ILE227

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site_id	AC6
Number of Residues	3
Details	binding site for residue EDO A 606

Chain	Residue
A	GLY190
A	HIS191
A	THR354

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site_id	AC7
Number of Residues	4
Details	binding site for residue EDO A 607

Chain	Residue
A	LYS140
A	LYS144
A	TYR151
A	ASN482

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site_id	AC8
Number of Residues	8
Details	binding site for residue EDO A 608

Chain	Residue
A	ALA51
A	ILE52
A	MET53
A	GLU67
A	CYS68
A	ASP69
A	GLN262
A	THR263

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site_id	AC9
Number of Residues	3
Details	binding site for residue EDO A 609

Chain	Residue
A	TYR184
A	ASP340
A	SER341

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