Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006259 | biological_process | DNA metabolic process |
| B | 0006265 | biological_process | DNA topological change |
| D | 0003677 | molecular_function | DNA binding |
| D | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0006259 | biological_process | DNA metabolic process |
| D | 0006265 | biological_process | DNA topological change |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue MN B 1501 |
| Chain | Residue |
| B | ASP508 |
| B | ASP510 |
| B | HOH1740 |
| B | HOH1765 |
| B | HOH1796 |
| D | HOH1714 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue 94K B 1502 |
| Chain | Residue |
| B | VAL1031 |
| B | MET1179 |
| B | ARG1342 |
| B | PRO1343 |
| B | HOH1826 |
| B | HOH1833 |
| B | ARG630 |
| B | ILE633 |
| B | GLU634 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue GOL B 1503 |
| Chain | Residue |
| B | GLU1251 |
| B | GLY1255 |
| B | ARG1256 |
| B | HOH1605 |
| B | HOH1861 |
| D | SER1315 |
| D | ASN1319 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue GOL B 1504 |
| Chain | Residue |
| B | ARG1047 |
| B | ARG1048 |
| B | ILE1147 |
| B | GLU1156 |
| B | HOH1673 |
| B | HOH1722 |
| B | HOH1746 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 1505 |
| Chain | Residue |
| B | GLU1190 |
| B | GLU1214 |
| B | ASP1482 |
| B | ASP1483 |
| B | ARG1484 |
| B | HOH1721 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue NA B 1506 |
| Chain | Residue |
| B | TYR1322 |
| B | LYS1323 |
| B | THR1325 |
| B | GLN1328 |
| B | HOH1926 |
| D | HOH1916 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue DMS B 1507 |
| Chain | Residue |
| B | PHE1097 |
| B | MET1113 |
| B | GLY1115 |
| B | HOH1904 |
| B | HOH1963 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue MN D 1501 |
| Chain | Residue |
| D | ASP508 |
| D | ASP510 |
| D | HOH1673 |
| D | HOH1683 |
| D | HOH1738 |
| F | HOH112 |
| site_id | AC9 |
| Number of Residues | 12 |
| Details | binding site for residue 94K D 1502 |
| Chain | Residue |
| D | ARG630 |
| D | ILE633 |
| D | GLU634 |
| D | ALA637 |
| D | VAL1031 |
| D | MET1179 |
| D | ARG1342 |
| D | PRO1343 |
| D | HOH1672 |
| D | HOH1828 |
| D | HOH1899 |
| D | HOH1965 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue GOL D 1503 |
| Chain | Residue |
| D | PRO1044 |
| D | ARG1047 |
| D | GLU1156 |
| D | HOH1688 |
| D | HOH1737 |
| D | HOH1837 |
| site_id | AD2 |
| Number of Residues | 8 |
| Details | binding site for residue GOL D 1504 |
| Chain | Residue |
| B | ARG1244 |
| B | ASN1319 |
| D | GLU1251 |
| D | GLY1255 |
| D | ARG1256 |
| D | GLN1257 |
| D | HOH1678 |
| D | HOH1754 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue GOL D 1505 |
| Chain | Residue |
| D | GLY1115 |
| D | GLN1267 |
| D | HOH1818 |
| D | HOH1866 |
| F | DC-5 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue GOL D 1506 |
| Chain | Residue |
| D | ASP1389 |
| D | HIS1390 |
| E | DA-8 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 101 |
| Chain | Residue |
| A | DG1 |
| A | DT2 |
| A | HOH216 |
| B | SER1084 |
| B | HOH1742 |
| E | DG-1 |
| site_id | AD6 |
| Number of Residues | 16 |
| Details | binding site for residue 6EJ C 101 |
| Chain | Residue |
| B | HOH1727 |
| B | HOH1855 |
| C | DT2 |
| C | DA3 |
| C | HOH219 |
| D | ALA1068 |
| D | MET1075 |
| D | ASP1083 |
| D | MET1121 |
| A | DT2 |
| A | DA3 |
| B | ALA1068 |
| B | GLY1072 |
| B | MET1075 |
| B | ASP1083 |
| B | MET1121 |
| site_id | AD7 |
| Number of Residues | 8 |
| Details | binding site for residue GOL C 102 |
| Chain | Residue |
| C | DG1 |
| C | DT2 |
| C | HOH206 |
| C | HOH208 |
| D | SER1084 |
| D | HOH1669 |
| F | DA-2 |
| F | DG-1 |
Functional Information from PROSITE/UniProt
| site_id | PS00177 |
| Number of Residues | 9 |
| Details | TOPOISOMERASE_II DNA topoisomerase II signature. LVEGDSAGG |
| Chain | Residue | Details |
| B | LEU433-GLY441 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| B | ASP510 | |
| D | GLU435 | |
| D | ASP508 | |
| D | ASP510 | |
| B | GLU435 | |
| B | ASP508 | |
| Chain | Residue | Details |
| B | LYS460 | |
| B | ASN463 | |
| D | LYS460 | |
| D | ASN463 | |
| Chain | Residue | Details |
| B | TYR1123 | |
| D | TYR1123 | |
