5NHC
Crystal structure of xylose isomerase from Piromyces E2 in complex with two Co2+ ions and xylulose
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0009045 | molecular_function | xylose isomerase activity |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0042732 | biological_process | D-xylose metabolic process |
| A | 0044577 | biological_process | D-xylose catabolic process to ethanol |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0009045 | molecular_function | xylose isomerase activity |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0042732 | biological_process | D-xylose metabolic process |
| B | 0044577 | biological_process | D-xylose catabolic process to ethanol |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0005975 | biological_process | carbohydrate metabolic process |
| C | 0009045 | molecular_function | xylose isomerase activity |
| C | 0016853 | molecular_function | isomerase activity |
| C | 0042732 | biological_process | D-xylose metabolic process |
| C | 0044577 | biological_process | D-xylose catabolic process to ethanol |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0005975 | biological_process | carbohydrate metabolic process |
| D | 0009045 | molecular_function | xylose isomerase activity |
| D | 0016853 | molecular_function | isomerase activity |
| D | 0042732 | biological_process | D-xylose metabolic process |
| D | 0044577 | biological_process | D-xylose catabolic process to ethanol |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue CO A 501 |
| Chain | Residue |
| A | GLU233 |
| A | GLU269 |
| A | ASP297 |
| A | ASP340 |
| A | XUL503 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue CO A 502 |
| Chain | Residue |
| A | XUL503 |
| A | HOH824 |
| A | GLU269 |
| A | HIS272 |
| A | ASP308 |
| A | ASP310 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | binding site for residue XUL A 503 |
| Chain | Residue |
| A | TRP50 |
| A | HIS102 |
| A | TRP140 |
| A | TRP189 |
| A | GLU233 |
| A | LYS235 |
| A | GLU269 |
| A | HIS272 |
| A | ASP297 |
| A | ASP308 |
| A | ASP340 |
| A | CO501 |
| A | CO502 |
| A | HOH824 |
| A | HOH845 |
| C | PHE61 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | binding site for residue HYP A 504 |
| Chain | Residue |
| A | LYS265 |
| A | GLY291 |
| A | MET292 |
| A | LEU293 |
| A | GLY329 |
| A | GLY331 |
| A | VAL333 |
| A | HOH608 |
| A | HOH621 |
| A | HOH685 |
| A | HOH896 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue CO B 501 |
| Chain | Residue |
| B | GLU233 |
| B | GLU269 |
| B | ASP297 |
| B | ASP340 |
| B | XUL503 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue CO B 502 |
| Chain | Residue |
| B | GLU269 |
| B | HIS272 |
| B | ASP308 |
| B | ASP310 |
| B | XUL503 |
| B | HOH758 |
| site_id | AC7 |
| Number of Residues | 15 |
| Details | binding site for residue XUL B 503 |
| Chain | Residue |
| B | TRP50 |
| B | HIS102 |
| B | TRP189 |
| B | GLU233 |
| B | LYS235 |
| B | GLU269 |
| B | HIS272 |
| B | ASP297 |
| B | ASP308 |
| B | ASP340 |
| B | CO501 |
| B | CO502 |
| B | HOH758 |
| B | HOH787 |
| D | PHE61 |
| site_id | AC8 |
| Number of Residues | 11 |
| Details | binding site for residue HYP B 504 |
| Chain | Residue |
| B | LYS265 |
| B | GLY291 |
| B | MET292 |
| B | LEU293 |
| B | GLY329 |
| B | GLY331 |
| B | VAL333 |
| B | HOH607 |
| B | HOH664 |
| B | HOH679 |
| B | HOH867 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue CO C 501 |
| Chain | Residue |
| C | GLU233 |
| C | GLU269 |
| C | ASP297 |
| C | ASP340 |
| C | XUL503 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue CO C 502 |
| Chain | Residue |
| C | GLU269 |
| C | HIS272 |
| C | ASP308 |
| C | ASP310 |
| C | XUL503 |
| C | HOH733 |
| site_id | AD2 |
| Number of Residues | 16 |
| Details | binding site for residue XUL C 503 |
| Chain | Residue |
| C | HOH733 |
| C | HOH780 |
| C | HOH830 |
| A | PHE61 |
| C | TRP50 |
| C | HIS102 |
| C | TRP189 |
| C | GLU233 |
| C | LYS235 |
| C | GLU269 |
| C | HIS272 |
| C | ASP297 |
| C | ASP308 |
| C | ASP340 |
| C | CO501 |
| C | CO502 |
| site_id | AD3 |
| Number of Residues | 12 |
| Details | binding site for residue HYP C 504 |
| Chain | Residue |
| C | LYS265 |
| C | GLY291 |
| C | MET292 |
| C | LEU293 |
| C | GLY329 |
| C | GLY331 |
| C | PHE332 |
| C | VAL333 |
| C | HOH602 |
| C | HOH649 |
| C | HOH675 |
| C | HOH752 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue CO D 501 |
| Chain | Residue |
| D | GLU233 |
| D | GLU269 |
| D | ASP297 |
| D | ASP340 |
| D | XUL503 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue CO D 502 |
| Chain | Residue |
| D | GLU269 |
| D | HIS272 |
| D | ASP308 |
| D | ASP310 |
| D | XUL503 |
| D | HOH761 |
| site_id | AD6 |
| Number of Residues | 15 |
| Details | binding site for residue XUL D 503 |
| Chain | Residue |
| B | PHE61 |
| D | TRP50 |
| D | HIS102 |
| D | TRP189 |
| D | GLU233 |
| D | LYS235 |
| D | GLU269 |
| D | HIS272 |
| D | ASP297 |
| D | ASP308 |
| D | ASP340 |
| D | CO501 |
| D | CO502 |
| D | HOH761 |
| D | HOH860 |
| site_id | AD7 |
| Number of Residues | 12 |
| Details | binding site for residue HYP D 504 |
| Chain | Residue |
| D | LYS265 |
| D | GLY291 |
| D | MET292 |
| D | LEU293 |
| D | GLY329 |
| D | GLY331 |
| D | VAL333 |
| D | HOH610 |
| D | HOH633 |
| D | HOH680 |
| D | HOH834 |
| D | HOH967 |
