5NFP
Glucocorticoid Receptor in complex with budesonide
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue CPS A 801 |
| Chain | Residue |
| A | TRP610 |
| A | ASP638 |
| A | TYR660 |
| A | TYR735 |
| A | GLN738 |
| A | THR739 |
| A | MET745 |
| A | GLN776 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 802 |
| Chain | Residue |
| A | ALA574 |
| A | TRP577 |
| A | MET604 |
| A | LYS667 |
| A | HOH922 |
| A | HOH971 |
| A | PRO541 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue GOL A 803 |
| Chain | Residue |
| A | ARG655 |
| A | ARG714 |
| site_id | AC4 |
| Number of Residues | 16 |
| Details | binding site for residue 8W5 A 804 |
| Chain | Residue |
| A | MET560 |
| A | LEU563 |
| A | ASN564 |
| A | GLY567 |
| A | GLN570 |
| A | MET604 |
| A | ARG611 |
| A | PHE623 |
| A | MET639 |
| A | GLN642 |
| A | TYR735 |
| A | CYS736 |
| A | THR739 |
| A | ILE747 |
| A | PHE749 |
| A | HOH957 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 165 |
| Details | Region: {"description":"Interaction with CRY1","evidences":[{"source":"PubMed","id":"22170608","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO)","evidences":[{"source":"PubMed","id":"12144530","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Motif: {"description":"LXXLL motif 3"} |
| Chain | Residue | Details |
