5NCV
Crystal Structure of Cytochrome c in complex with p-Methylphosphonatocalix[4]arene
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005758 | cellular_component | mitochondrial intermembrane space |
| A | 0006122 | biological_process | mitochondrial electron transport, ubiquinol to cytochrome c |
| A | 0006123 | biological_process | mitochondrial electron transport, cytochrome c to oxygen |
| A | 0009055 | molecular_function | electron transfer activity |
| A | 0020037 | molecular_function | heme binding |
| A | 0022904 | biological_process | respiratory electron transport chain |
| A | 0046872 | molecular_function | metal ion binding |
| A | 1901612 | molecular_function | cardiolipin binding |
| B | 0005515 | molecular_function | protein binding |
| B | 0005739 | cellular_component | mitochondrion |
| B | 0005758 | cellular_component | mitochondrial intermembrane space |
| B | 0006122 | biological_process | mitochondrial electron transport, ubiquinol to cytochrome c |
| B | 0006123 | biological_process | mitochondrial electron transport, cytochrome c to oxygen |
| B | 0009055 | molecular_function | electron transfer activity |
| B | 0020037 | molecular_function | heme binding |
| B | 0022904 | biological_process | respiratory electron transport chain |
| B | 0046872 | molecular_function | metal ion binding |
| B | 1901612 | molecular_function | cardiolipin binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | binding site for residue HEC A 201 |
| Chain | Residue |
| A | ARG13 |
| A | TYR48 |
| A | THR49 |
| A | ASN52 |
| A | TRP59 |
| A | MET64 |
| A | TYR67 |
| A | THR78 |
| A | LYS79 |
| A | MET80 |
| A | HOH304 |
| A | CYS14 |
| A | HOH345 |
| A | CYS17 |
| A | HIS18 |
| A | VAL28 |
| A | ILE35 |
| A | SER40 |
| A | GLY41 |
| A | TYR46 |
| site_id | AC2 |
| Number of Residues | 21 |
| Details | binding site for residue 8TE A 202 |
| Chain | Residue |
| A | ASP50 |
| A | ALA51 |
| A | ILE53 |
| A | LYS54 |
| A | ASN56 |
| A | HOH305 |
| A | HOH309 |
| A | HOH310 |
| A | HOH314 |
| A | HOH318 |
| A | HOH323 |
| A | HOH325 |
| A | HOH328 |
| A | HOH332 |
| A | HOH342 |
| A | HOH392 |
| A | HOH402 |
| A | HOH406 |
| B | LYS22 |
| B | LYS27 |
| B | HOH355 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | binding site for residue 8TE A 203 |
| Chain | Residue |
| A | ASN70 |
| A | GLY83 |
| A | LYS86 |
| A | HOH306 |
| A | HOH311 |
| A | HOH320 |
| A | HOH335 |
| A | HOH339 |
| A | HOH398 |
| A | HOH418 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue CL A 204 |
| Chain | Residue |
| A | LYS27 |
| A | ASN63 |
| A | TYR74 |
| A | HOH367 |
| A | HOH447 |
| site_id | AC5 |
| Number of Residues | 15 |
| Details | binding site for residue 8TE B 202 |
| Chain | Residue |
| B | ARG13 |
| B | THR69 |
| B | GLY83 |
| B | LYS86 |
| B | LYS87 |
| B | HOH304 |
| B | HOH305 |
| B | HOH307 |
| B | HOH308 |
| B | HOH319 |
| B | HOH331 |
| B | HOH340 |
| B | HOH358 |
| B | HOH374 |
| B | HOH379 |
| site_id | AC6 |
| Number of Residues | 24 |
| Details | binding site for Di-peptide HEC B 201 and CYS B 17 |
| Chain | Residue |
| B | ARG13 |
| B | CYS14 |
| B | LEU15 |
| B | GLN16 |
| B | HIS18 |
| B | LYS27 |
| B | VAL28 |
| B | GLY29 |
| B | ILE35 |
| B | SER40 |
| B | GLY41 |
| B | TYR46 |
| B | TYR48 |
| B | THR49 |
| B | ASN52 |
| B | TRP59 |
| B | MET64 |
| B | TYR67 |
| B | THR78 |
| B | LYS79 |
| B | MET80 |
| B | LEU94 |
| B | HOH325 |
| B | HOH329 |
| site_id | AC7 |
| Number of Residues | 23 |
| Details | binding site for Di-peptide HEC B 201 and CYS B 14 |
| Chain | Residue |
| B | CYS17 |
| B | HIS18 |
| B | VAL28 |
| B | ILE35 |
| B | SER40 |
| B | GLY41 |
| B | TYR46 |
| B | TYR48 |
| B | THR49 |
| B | ASN52 |
| B | TRP59 |
| B | MET64 |
| B | TYR67 |
| B | THR78 |
| B | LYS79 |
| B | MET80 |
| B | LEU94 |
| B | HOH325 |
| B | HOH329 |
| B | PHE10 |
| B | ARG13 |
| B | LEU15 |
| B | GLN16 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Binding site: {"description":"covalent","evidences":[{"source":"PubMed","id":"11880631","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18390544","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1KYO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CX5","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"description":"axial binding residue","evidences":[{"source":"PubMed","id":"11880631","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18390544","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1KYO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CX5","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6,N6,N6-trimethyllysine; by CTM1","evidences":[{"source":"PubMed","id":"10791961","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11880631","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1KYO","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6,N6,N6-trimethyllysine","evidences":[{"source":"PubMed","id":"10821864","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18390544","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
