5NCR

OH1 from the Orf virus: a tyrosine phosphatase that displays distinct structural features and triple substrate specificity

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004721	molecular_function	phosphoprotein phosphatase activity
A	0006470	biological_process	protein dephosphorylation
A	0008330	molecular_function	protein tyrosine/threonine phosphatase activity
A	0016311	biological_process	dephosphorylation
A	0017017	molecular_function	MAP kinase tyrosine/serine/threonine phosphatase activity
A	0019049	biological_process	virus-mediated perturbation of host defense response
A	0030430	cellular_component	host cell cytoplasm
A	0033550	molecular_function	MAP kinase tyrosine phosphatase activity
A	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
A	0039563	biological_process	symbiont-mediated suppression of host JAK-STAT cascade via inhibition of STAT1 activity
A	0043409	biological_process	negative regulation of MAPK cascade
A	0052170	biological_process	symbiont-mediated suppression of host innate immune response
B	0004721	molecular_function	phosphoprotein phosphatase activity
B	0006470	biological_process	protein dephosphorylation
B	0008330	molecular_function	protein tyrosine/threonine phosphatase activity
B	0016311	biological_process	dephosphorylation
B	0017017	molecular_function	MAP kinase tyrosine/serine/threonine phosphatase activity
B	0019049	biological_process	virus-mediated perturbation of host defense response
B	0030430	cellular_component	host cell cytoplasm
B	0033550	molecular_function	MAP kinase tyrosine phosphatase activity
B	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
B	0039563	biological_process	symbiont-mediated suppression of host JAK-STAT cascade via inhibition of STAT1 activity
B	0043409	biological_process	negative regulation of MAPK cascade
B	0052170	biological_process	symbiont-mediated suppression of host innate immune response

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	binding site for residue PO4 A 200

Chain	Residue
A	ASP81
A	SER112
A	VAL113
A	ALA114
A	GLY115
A	VAL116
A	ASN117
A	ARG118
A	HOH302

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site_id	AC2
Number of Residues	8
Details	binding site for residue PO4 B 201

Chain	Residue
B	ASP81
B	SER112
B	ALA114
B	GLY115
B	VAL116
B	ASN117
B	ARG118
B	HOH303

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site_id	AC3
Number of Residues	4
Details	binding site for residue SO4 B 202

Chain	Residue
B	THR62
B	MET63
B	VAL113
B	ARG118

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