Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0006508 | biological_process | proteolysis |
| A | 0006956 | biological_process | complement activation |
| A | 0006957 | biological_process | complement activation, alternative pathway |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| A | 0009617 | biological_process | response to bacterium |
| A | 0031093 | cellular_component | platelet alpha granule lumen |
| A | 0034774 | cellular_component | secretory granule lumen |
| A | 0070062 | cellular_component | extracellular exosome |
| A | 1904813 | cellular_component | ficolin-1-rich granule lumen |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 301 |
| Chain | Residue |
| A | ASP129 |
| A | VAL130 |
| A | VAL162 |
| A | LEU163 |
| A | ASP164 |
| A | ARG165 |
| A | MET181 |
| A | CYS182 |
| A | HOH489 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 302 |
| Chain | Residue |
| A | LEU135 |
| A | VAL200 |
| A | CYS201 |
| A | GLY202 |
| A | GLY207 |
| A | HOH441 |
| site_id | AC3 |
| Number of Residues | 19 |
| Details | binding site for residue 8RT A 303 |
| Chain | Residue |
| A | HIS40 |
| A | LEU41 |
| A | CYS42 |
| A | HIS57 |
| A | CYS58 |
| A | TRP141 |
| A | GLY142 |
| A | ILE143 |
| A | ARG151 |
| A | CYS191 |
| A | LYS192 |
| A | GLY193 |
| A | SER195 |
| A | SER215 |
| A | GLY216 |
| A | SER217 |
| A | ARG218 |
| A | HOH498 |
| A | HOH526 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LSAAHC |
| Chain | Residue | Details |
| A | LEU53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DSckGDSGGPLV |
| Chain | Residue | Details |
| A | ASP189-VAL200 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Charge relay system |
| Chain | Residue | Details |
| A | HIS57 | |
| A | ASP102 | |
| A | SER195 | |
