5NA4

NADH:quinone oxidoreductase (NDH-II) from Staphylococcus aureus - E172S mutant

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003955	molecular_function	NAD(P)H dehydrogenase (quinone) activity
A	0005886	cellular_component	plasma membrane
A	0016491	molecular_function	oxidoreductase activity
A	0019646	biological_process	aerobic electron transport chain
A	0050136	molecular_function	NADH:ubiquinone reductase (non-electrogenic) activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	32
Details	binding site for residue FAD A 1001

Chain	Residue
A	GLY12
A	HIS51
A	ALA81
A	GLU82
A	VAL83
A	LEU109
A	GLY110
A	PHE111
A	PHE168
A	THR169
A	LEU270
A	GLY14
A	GLY301
A	ASP302
A	THR317
A	THR318
A	ALA319
A	GLN320
A	LYS379
A	HOH1101
A	HOH1104
A	HOH1110
A	TYR15
A	HOH1113
A	HOH1116
A	HOH1125
A	ALA16
A	ASN39
A	LYS40
A	ASN41
A	ALA47
A	THR48

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: ACT_SITE => ECO:0000305|PubMed:28181562, ECO:0000305|PubMed:28801048

Chain	Residue	Details
A	SER172

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site_id	SWS_FT_FI2
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269|PubMed:28801048

Chain	Residue	Details
A	GLY12
A	ASN39
A	VAL83
A	ASP302
A	ALA319
A	LYS379

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