5N6T
Thermotoga maritima family 1 glycoside hydrolase complexed with a cyclophellitol analogue transition state mimic
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000272 | biological_process | polysaccharide catabolic process |
| A | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0008422 | molecular_function | beta-glucosidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| A | 0030245 | biological_process | cellulose catabolic process |
| B | 0000272 | biological_process | polysaccharide catabolic process |
| B | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0008422 | molecular_function | beta-glucosidase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| B | 0030245 | biological_process | cellulose catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 501 |
| Chain | Residue |
| A | ARG137 |
| A | HOH742 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 502 |
| Chain | Residue |
| A | ARG240 |
| A | HIS243 |
| A | LYS337 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 503 |
| Chain | Residue |
| A | HOH663 |
| A | GLU405 |
| A | 8P2505 |
| A | HOH601 |
| A | HOH605 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 504 |
| Chain | Residue |
| A | VAL53 |
| A | ALA54 |
| A | TYR410 |
| A | TYR421 |
| A | GLN424 |
| site_id | AC5 |
| Number of Residues | 13 |
| Details | binding site for residue 8P2 A 505 |
| Chain | Residue |
| A | GLN20 |
| A | HIS121 |
| A | ASN165 |
| A | GLU166 |
| A | TYR295 |
| A | TRP324 |
| A | GLU351 |
| A | TRP398 |
| A | GLU405 |
| A | TRP406 |
| A | PHE414 |
| A | EDO503 |
| A | HOH601 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 501 |
| Chain | Residue |
| B | ARG237 |
| B | PHE241 |
| B | ALA308 |
| B | LYS309 |
| B | VAL310 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 502 |
| Chain | Residue |
| B | ASN222 |
| B | ASN223 |
| B | GLY224 |
| B | ASN246 |
| B | ASN247 |
| B | HIS298 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 503 |
| Chain | Residue |
| A | HOH649 |
| B | TYR177 |
| B | PRO307 |
| site_id | AC9 |
| Number of Residues | 12 |
| Details | binding site for residue 8P2 B 504 |
| Chain | Residue |
| B | GLN20 |
| B | HIS121 |
| B | ASN165 |
| B | GLU166 |
| B | TYR295 |
| B | TRP324 |
| B | GLU351 |
| B | TRP398 |
| B | GLU405 |
| B | TRP406 |
| B | PHE414 |
| B | HOH607 |
Functional Information from PROSITE/UniProt
| site_id | PS00572 |
| Number of Residues | 9 |
| Details | GLYCOSYL_HYDROL_F1_1 Glycosyl hydrolases family 1 active site. VYITENGAA |
| Chain | Residue | Details |
| A | VAL347-ALA355 |
| site_id | PS00653 |
| Number of Residues | 15 |
| Details | GLYCOSYL_HYDROL_F1_2 Glycosyl hydrolases family 1 N-terminal signature. FlWGvAtASYQiEgS |
| Chain | Residue | Details |
| A | PHE10-SER24 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PROSITE-ProRule","id":"PRU10055","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
