Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5N5V

Structure of p-boronophenylalanyl tRNA synthetase - apo form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004812	molecular_function	aminoacyl-tRNA ligase activity
A	0004831	molecular_function	tyrosine-tRNA ligase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0006412	biological_process	translation
A	0006418	biological_process	tRNA aminoacylation for protein translation
A	0006437	biological_process	tyrosyl-tRNA aminoacylation
B	0000166	molecular_function	nucleotide binding
B	0004812	molecular_function	aminoacyl-tRNA ligase activity
B	0004831	molecular_function	tyrosine-tRNA ligase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0006412	biological_process	translation
B	0006418	biological_process	tRNA aminoacylation for protein translation
B	0006437	biological_process	tyrosyl-tRNA aminoacylation
C	0000166	molecular_function	nucleotide binding
C	0004812	molecular_function	aminoacyl-tRNA ligase activity
C	0004831	molecular_function	tyrosine-tRNA ligase activity
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0006412	biological_process	translation
C	0006418	biological_process	tRNA aminoacylation for protein translation
C	0006437	biological_process	tyrosyl-tRNA aminoacylation
D	0000166	molecular_function	nucleotide binding
D	0004812	molecular_function	aminoacyl-tRNA ligase activity
D	0004831	molecular_function	tyrosine-tRNA ligase activity
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0006412	biological_process	translation
D	0006418	biological_process	tRNA aminoacylation for protein translation
D	0006437	biological_process	tyrosyl-tRNA aminoacylation
E	0000166	molecular_function	nucleotide binding
E	0004812	molecular_function	aminoacyl-tRNA ligase activity
E	0004831	molecular_function	tyrosine-tRNA ligase activity
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0006412	biological_process	translation
E	0006418	biological_process	tRNA aminoacylation for protein translation
E	0006437	biological_process	tyrosyl-tRNA aminoacylation
F	0000166	molecular_function	nucleotide binding
F	0004812	molecular_function	aminoacyl-tRNA ligase activity
F	0004831	molecular_function	tyrosine-tRNA ligase activity
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0006412	biological_process	translation
F	0006418	biological_process	tRNA aminoacylation for protein translation
F	0006437	biological_process	tyrosyl-tRNA aminoacylation
G	0000166	molecular_function	nucleotide binding
G	0004812	molecular_function	aminoacyl-tRNA ligase activity
G	0004831	molecular_function	tyrosine-tRNA ligase activity
G	0005524	molecular_function	ATP binding
G	0005737	cellular_component	cytoplasm
G	0006412	biological_process	translation
G	0006418	biological_process	tRNA aminoacylation for protein translation
G	0006437	biological_process	tyrosyl-tRNA aminoacylation
H	0000166	molecular_function	nucleotide binding
H	0004812	molecular_function	aminoacyl-tRNA ligase activity
H	0004831	molecular_function	tyrosine-tRNA ligase activity
H	0005524	molecular_function	ATP binding
H	0005737	cellular_component	cytoplasm
H	0006412	biological_process	translation
H	0006418	biological_process	tRNA aminoacylation for protein translation
H	0006437	biological_process	tyrosyl-tRNA aminoacylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue CL A 401

Chain	Residue
A	ARG257
A	LEU282
A	HIS283
A	ARG286

site_id	AC2
Number of Residues	2
Details	binding site for residue CL B 401

Chain	Residue
B	ARG257
B	HIS283

site_id	AC3
Number of Residues	3
Details	binding site for residue CL D 401

Chain	Residue
D	ARG257
D	HIS283
D	ARG286

site_id	AC4
Number of Residues	3
Details	binding site for residue CL E 401

Chain	Residue
E	ARG257
E	HIS283
E	ARG286

site_id	AC5
Number of Residues	2
Details	binding site for residue CL G 401

Chain	Residue
G	HIS283
G	ARG286

Functional Information from PROSITE/UniProt

site_id	PS00178
Number of Residues	10
Details	AA_TRNA_LIGASE_I Aminoacyl-transfer RNA synthetases class-I signature. P..SGkIHLGHY

Chain	Residue	Details
A	PRO37-TYR46

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	BINDING: BINDING => ECO:0000269\|PubMed:12754495

Chain	Residue	Details
A	SER32
D	SER32
D	GLU36
D	GLN173
E	SER32
E	GLU36
E	GLN173
F	SER32
F	GLU36
F	GLN173
G	SER32
A	GLU36
G	GLU36
G	GLN173
H	SER32
H	GLU36
H	GLN173
A	GLN173
B	SER32
B	GLU36
B	GLN173
C	SER32
C	GLU36
C	GLN173

site_id	SWS_FT_FI2
Number of Residues	8
Details	BINDING: BINDING => ECO:0000255

Chain	Residue	Details
A	SER207
B	SER207
C	SER207
D	SER207
E	SER207
F	SER207
G	SER207
H	SER207

site_id	SWS_FT_FI3
Number of Residues	8
Details	SITE: Interaction with t-RNA

Chain	Residue	Details
A	ASN143
B	ASN143
C	ASN143
D	ASN143
E	ASN143
F	ASN143
G	ASN143
H	ASN143

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)