Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0070012 | molecular_function | oligopeptidase activity |
| B | 0004252 | molecular_function | serine-type endopeptidase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006508 | biological_process | proteolysis |
| B | 0008233 | molecular_function | peptidase activity |
| B | 0008236 | molecular_function | serine-type peptidase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0070012 | molecular_function | oligopeptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | binding site for residue GOL A 801 |
| Chain | Residue |
| A | GLN59 |
| A | HOH1466 |
| B | LYS389 |
| A | LEU62 |
| A | ASP63 |
| A | ILE68 |
| A | GLN69 |
| A | LYS709 |
| A | ASP713 |
| A | HOH1082 |
| A | HOH1215 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 802 |
| Chain | Residue |
| A | SER421 |
| A | PRO426 |
| A | PHE506 |
| A | PHE507 |
| A | HOH943 |
| A | HOH1073 |
| A | HOH1103 |
| A | HOH1136 |
| C | ASP15 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue GOL B 801 |
| Chain | Residue |
| B | SER421 |
| B | PRO426 |
| B | PHE506 |
| B | PHE507 |
| B | HOH1105 |
| B | HOH1107 |
| D | ASP15 |
| D | HOH208 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue GOL D 101 |
| Chain | Residue |
| B | ASN409 |
| B | ARG410 |
| B | GLN411 |
| B | HOH1256 |
| B | HOH1321 |
| D | CYS25 |
| D | HOH203 |
| D | HOH205 |
Functional Information from PROSITE/UniProt
| site_id | PS00708 |
| Number of Residues | 31 |
| Details | PRO_ENDOPEP_SER Prolyl endopeptidase family serine active site. DfiaAaqfLvknkyaapgkvainGaSnGGLL |
| Chain | Residue | Details |
| A | ASP552-LEU582 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Active site: {"description":"Charge relay system","evidences":[{"source":"PROSITE-ProRule","id":"PRU10084","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"29051530","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 32 |
| Details | Propeptide: {"featureId":"PRO_0000443566","evidences":[{"source":"UniProtKB","id":"A8W7M4","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"4-hydroxyproline","evidences":[{"source":"UniProtKB","id":"P85421","evidenceCode":"ECO:0000250"}]} |
