5N2I

F420:NADPH oxidoreductase from Thermobifida fusca with NADP+ bound

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0006740	biological_process	NADPH regeneration
A	0016491	molecular_function	oxidoreductase activity
A	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
A	0050661	molecular_function	NADP binding
A	0070967	molecular_function	coenzyme F420 binding
B	0000166	molecular_function	nucleotide binding
B	0006740	biological_process	NADPH regeneration
B	0016491	molecular_function	oxidoreductase activity
B	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
B	0050661	molecular_function	NADP binding
B	0070967	molecular_function	coenzyme F420 binding
C	0000166	molecular_function	nucleotide binding
C	0006740	biological_process	NADPH regeneration
C	0016491	molecular_function	oxidoreductase activity
C	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
C	0050661	molecular_function	NADP binding
C	0070967	molecular_function	coenzyme F420 binding
D	0000166	molecular_function	nucleotide binding
D	0006740	biological_process	NADPH regeneration
D	0016491	molecular_function	oxidoreductase activity
D	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
D	0050661	molecular_function	NADP binding
D	0070967	molecular_function	coenzyme F420 binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	28
Details	binding site for residue NAP A 301

Chain	Residue
A	GLY26
A	VAL88
A	PRO89
A	GLY92
A	CYS112
A	VAL113
A	ASN114
A	PHE150
A	HIS151
A	VAL153
A	ALA155
A	THR28
A	HOH401
A	HOH415
A	HOH418
A	HOH432
A	HOH435
A	HOH466
A	HOH470
A	HOH471
A	HOH493
A	GLY29
A	ASP30
A	GLN31
A	SER50
A	ARG51
A	ARG55
A	ALA87

---

site_id	AC2
Number of Residues	9
Details	binding site for residue GOL A 302

Chain	Residue
A	GLY174
A	ASP175
A	ARG177
A	THR180
A	TYR197
A	ARG200
B	ARG220
D	PRO142
D	ASP143

---

site_id	AC3
Number of Residues	8
Details	binding site for residue GOL A 303

Chain	Residue
A	GLU65
A	HOH405
A	HOH417
A	HOH441
C	SER216
C	ARG219
C	ARG220
D	TYR197

---

site_id	AC4
Number of Residues	5
Details	binding site for residue GOL A 304

Chain	Residue
A	TRP90
A	ASP91
A	HIS93
A	ARG94
A	GLN136

---

site_id	AC5
Number of Residues	7
Details	binding site for residue GOL A 305

Chain	Residue
A	VAL153
A	ASN218
A	HIS224
A	ALA225
A	HOH401
A	HOH425
A	HOH457

---

site_id	AC6
Number of Residues	25
Details	binding site for residue NAP B 301

Chain	Residue
B	GLY26
B	THR28
B	GLY29
B	ASP30
B	GLN31
B	SER50
B	ARG51
B	ARG55
B	ALA87
B	VAL88
B	PRO89
B	GLY92
B	CYS112
B	VAL113
B	ASN114
B	PHE150
B	HIS151
B	VAL153
B	ALA155
B	HOH405
B	HOH411
B	HOH424
B	HOH429
B	HOH460
B	HOH486

---

site_id	AC7
Number of Residues	8
Details	binding site for residue GOL B 302

Chain	Residue
B	HIS152
B	LEU214
B	ASN218
B	HIS224
B	ALA225
B	HOH417
B	HOH439
B	HOH451

---

site_id	AC8
Number of Residues	28
Details	binding site for residue NAP C 301

Chain	Residue
C	VAL88
C	PRO89
C	GLY92
C	CYS112
C	VAL113
C	ASN114
C	PHE150
C	HIS151
C	VAL153
C	ALA155
C	HOH402
C	HOH412
C	HOH413
C	HOH414
C	HOH419
C	HOH460
C	HOH469
C	HOH470
C	HOH472
C	GLY26
C	THR28
C	GLY29
C	ASP30
C	GLN31
C	SER50
C	ARG51
C	ARG55
C	ALA87

---

site_id	AC9
Number of Residues	8
Details	binding site for residue GOL C 302

Chain	Residue
B	ASP143
C	GLY174
C	ASP175
C	ARG177
C	THR180
C	TYR197
C	ARG200
D	ARG220

---

site_id	AD1
Number of Residues	27
Details	binding site for residue NAP D 301

Chain	Residue
D	GLY26
D	THR28
D	GLY29
D	ASP30
D	GLN31
D	SER50
D	ARG51
D	ARG55
D	ALA87
D	VAL88
D	PRO89
D	GLY92
D	CYS112
D	VAL113
D	ASN114
D	PHE150
D	HIS151
D	VAL153
D	ALA155
D	HOH401
D	HOH413
D	HOH419
D	HOH421
D	HOH440
D	HOH459
D	HOH475
D	HOH491

---

site_id	AD2
Number of Residues	8
Details	binding site for residue GOL D 302

Chain	Residue
D	HIS152
D	THR211
D	LEU214
D	ILE215
D	ASN218
D	HIS224
D	ALA225
D	HOH429

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