5MXQ

Crystal Structure of the Acquired VIM-2 Metallo-beta-Lactamase in Complex with ANT-90 Inhibitor

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016787	molecular_function	hydrolase activity
A	0017001	biological_process	antibiotic catabolic process
A	0042597	cellular_component	periplasmic space
A	0046677	biological_process	response to antibiotic
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 301

Chain	Residue
A	HIS153
A	HIS251
A	ACT306
A	ACT307

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site_id	AC2
Number of Residues	4
Details	binding site for residue ZN A 302

Chain	Residue
A	HIS114
A	HIS116
A	HIS179
A	HOH418

---

site_id	AC3
Number of Residues	5
Details	binding site for residue ZN A 303

Chain	Residue
A	CYS198
A	HIS240
A	U8K304
A	HOH418
A	ASP118

---

site_id	AC4
Number of Residues	6
Details	binding site for residue ACT A 306

Chain	Residue
A	ALA132
A	HIS153
A	HIS251
A	ASN254
A	ZN301
A	ACT307

---

site_id	AC5
Number of Residues	8
Details	binding site for residue ACT A 307

Chain	Residue
A	ALA132
A	THR133
A	THR152
A	HIS153
A	HIS251
A	ZN301
A	ACT306
A	HOH423

---

site_id	AC6
Number of Residues	15
Details	binding site for residues U8K A 304 and CL A 305

Chain	Residue
A	PHE62
A	TYR67
A	TRP87
A	ASP118
A	HIS179
A	CYS198
A	ARG205
A	GLY209
A	ASN210
A	HIS240
A	ZN303
A	HOH418
A	HOH429
A	HOH439
A	HOH462

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