5MX9
High resolution crystal structure of the MCR-2 catalytic domain
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016772 | molecular_function | transferase activity, transferring phosphorus-containing groups |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 601 |
| Chain | Residue |
| A | HIS395 |
| A | GLU405 |
| A | HIS478 |
| A | HOH715 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 602 |
| Chain | Residue |
| A | GLU246 |
| A | THR285 |
| A | ASP465 |
| A | HIS466 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 603 |
| Chain | Residue |
| A | THR502 |
| A | LYS523 |
| A | ASP526 |
| A | GLN540 |
| A | HOH732 |
| A | HOH930 |
| A | HOH959 |
| A | ARG238 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 604 |
| Chain | Residue |
| A | ASP331 |
| A | SER332 |
| A | LYS333 |
| A | GLY334 |
| A | ASP337 |
| A | TYR344 |
| A | HOH784 |
| A | HOH822 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 605 |
| Chain | Residue |
| A | GLU418 |
| A | LEU419 |
| A | ALA420 |
| A | HOH717 |
| A | HOH873 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"28777086","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30194678","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"32432618","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5MX9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6A7W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6SUT","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"32432618","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6SUT","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
