5MX7

1a,20S-dihydroxyvitamin D3 VDR complex

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A1	0003677	molecular_function	DNA binding
A1	0004879	molecular_function	nuclear receptor activity
A1	0005634	cellular_component	nucleus
A1	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	binding site for residue D3V A1 4000

Chain	Residue
A1	TYR175
A1	VAL328
A1	HIS333
A1	HIS423
A1	VAL262
A1	SER265
A1	ILE299
A1	ARG302
A1	SER303
A1	SER306
A1	TRP314
A1	CYS316

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	18
Details	Region: {"description":"Interaction with coactivator LXXLL motif","evidences":[{"source":"UniProtKB","id":"P13053","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	8
Details	Motif: {"description":"9aaTAD","evidences":[{"source":"UniProtKB","id":"P11473","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17218092","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2HC4","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	4
Details	Motif: {"description":"LXXLL motif 4"}

Chain

Residue

Details

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