5MW8
INOSITOL 1,3,4,5,6-PENTAKISPHOSPHATE 2-KINASE FROM M. MUSCULUS IN COMPLEX WITH ATP and IP5
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016301 | molecular_function | kinase activity |
| A | 0035299 | molecular_function | inositol-1,3,4,5,6-pentakisphosphate 2-kinase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | binding site for residue ATP A 501 |
| Chain | Residue |
| A | HIS14 |
| A | PRO116 |
| A | ASN117 |
| A | LEU118 |
| A | GLU136 |
| A | LYS138 |
| A | ASP400 |
| A | LEU436 |
| A | ASP437 |
| A | 5MY502 |
| A | MG504 |
| A | GLU16 |
| A | MG505 |
| A | HOH611 |
| A | GLY17 |
| A | ASN18 |
| A | LYS19 |
| A | SER20 |
| A | VAL22 |
| A | VAL31 |
| A | ARG33 |
| site_id | AC2 |
| Number of Residues | 22 |
| Details | binding site for residue 5MY A 502 |
| Chain | Residue |
| A | ASN18 |
| A | LYS19 |
| A | ARG100 |
| A | LYS138 |
| A | LYS140 |
| A | ARG160 |
| A | HIS164 |
| A | LYS168 |
| A | LYS173 |
| A | ASN206 |
| A | MET396 |
| A | ASP400 |
| A | LYS441 |
| A | GLN449 |
| A | LEU452 |
| A | ATP501 |
| A | MG504 |
| A | HOH602 |
| A | HOH603 |
| A | HOH611 |
| A | HOH614 |
| A | HOH617 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 503 |
| Chain | Residue |
| A | CYS159 |
| A | CYS162 |
| A | CYS181 |
| A | CYS291 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 504 |
| Chain | Residue |
| A | ASP437 |
| A | ASP439 |
| A | LYS441 |
| A | ATP501 |
| A | 5MY502 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue MG A 505 |
| Chain | Residue |
| A | ASP437 |
| A | ATP501 |
| A | HOH606 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | binding site for residue ACT A 506 |
