5MVA

Structure of the thin filament at high calcium concentration

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0001725	cellular_component	stress fiber
A	0003785	molecular_function	actin monomer binding
A	0005509	molecular_function	calcium ion binding
A	0005515	molecular_function	protein binding
A	0005523	molecular_function	tropomyosin binding
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005856	cellular_component	cytoskeleton
A	0005865	cellular_component	striated muscle thin filament
A	0005884	cellular_component	actin filament
A	0010628	biological_process	positive regulation of gene expression
A	0016787	molecular_function	hydrolase activity
A	0019904	molecular_function	protein domain specific binding
A	0030027	cellular_component	lamellipodium
A	0030041	biological_process	actin filament polymerization
A	0030175	cellular_component	filopodium
A	0030240	biological_process	skeletal muscle thin filament assembly
A	0031013	molecular_function	troponin I binding
A	0031432	molecular_function	titin binding
A	0031941	cellular_component	filamentous actin
A	0032036	molecular_function	myosin heavy chain binding
A	0032432	cellular_component	actin filament bundle
A	0042802	molecular_function	identical protein binding
A	0044297	cellular_component	cell body
A	0048306	molecular_function	calcium-dependent protein binding
A	0048741	biological_process	skeletal muscle fiber development
A	0051017	biological_process	actin filament bundle assembly
A	0090131	biological_process	mesenchyme migration
A	0098723	cellular_component	skeletal muscle myofibril
A	0140660	molecular_function	cytoskeletal motor activator activity
B	0000287	molecular_function	magnesium ion binding
B	0001725	cellular_component	stress fiber
B	0003785	molecular_function	actin monomer binding
B	0005509	molecular_function	calcium ion binding
B	0005515	molecular_function	protein binding
B	0005523	molecular_function	tropomyosin binding
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005856	cellular_component	cytoskeleton
B	0005865	cellular_component	striated muscle thin filament
B	0005884	cellular_component	actin filament
B	0010628	biological_process	positive regulation of gene expression
B	0016787	molecular_function	hydrolase activity
B	0019904	molecular_function	protein domain specific binding
B	0030027	cellular_component	lamellipodium
B	0030041	biological_process	actin filament polymerization
B	0030175	cellular_component	filopodium
B	0030240	biological_process	skeletal muscle thin filament assembly
B	0031013	molecular_function	troponin I binding
B	0031432	molecular_function	titin binding
B	0031941	cellular_component	filamentous actin
B	0032036	molecular_function	myosin heavy chain binding
B	0032432	cellular_component	actin filament bundle
B	0042802	molecular_function	identical protein binding
B	0044297	cellular_component	cell body
B	0048306	molecular_function	calcium-dependent protein binding
B	0048741	biological_process	skeletal muscle fiber development
B	0051017	biological_process	actin filament bundle assembly
B	0090131	biological_process	mesenchyme migration
B	0098723	cellular_component	skeletal muscle myofibril
B	0140660	molecular_function	cytoskeletal motor activator activity
C	0000287	molecular_function	magnesium ion binding
C	0001725	cellular_component	stress fiber
C	0003785	molecular_function	actin monomer binding
C	0005509	molecular_function	calcium ion binding
C	0005515	molecular_function	protein binding
C	0005523	molecular_function	tropomyosin binding
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0005856	cellular_component	cytoskeleton
C	0005865	cellular_component	striated muscle thin filament
C	0005884	cellular_component	actin filament
C	0010628	biological_process	positive regulation of gene expression
C	0016787	molecular_function	hydrolase activity
C	0019904	molecular_function	protein domain specific binding
C	0030027	cellular_component	lamellipodium
C	0030041	biological_process	actin filament polymerization
C	0030175	cellular_component	filopodium
C	0030240	biological_process	skeletal muscle thin filament assembly
C	0031013	molecular_function	troponin I binding
C	0031432	molecular_function	titin binding
C	0031941	cellular_component	filamentous actin
C	0032036	molecular_function	myosin heavy chain binding
C	0032432	cellular_component	actin filament bundle
C	0042802	molecular_function	identical protein binding
C	0044297	cellular_component	cell body
C	0048306	molecular_function	calcium-dependent protein binding
C	0048741	biological_process	skeletal muscle fiber development
C	0051017	biological_process	actin filament bundle assembly
C	0090131	biological_process	mesenchyme migration
C	0098723	cellular_component	skeletal muscle myofibril
C	0140660	molecular_function	cytoskeletal motor activator activity
D	0000287	molecular_function	magnesium ion binding
D	0001725	cellular_component	stress fiber
D	0003785	molecular_function	actin monomer binding
D	0005509	molecular_function	calcium ion binding
D	0005515	molecular_function	protein binding
D	0005523	molecular_function	tropomyosin binding
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0005856	cellular_component	cytoskeleton
D	0005865	cellular_component	striated muscle thin filament
D	0005884	cellular_component	actin filament
D	0010628	biological_process	positive regulation of gene expression
D	0016787	molecular_function	hydrolase activity
D	0019904	molecular_function	protein domain specific binding
D	0030027	cellular_component	lamellipodium
D	0030041	biological_process	actin filament polymerization
D	0030175	cellular_component	filopodium
D	0030240	biological_process	skeletal muscle thin filament assembly
D	0031013	molecular_function	troponin I binding
D	0031432	molecular_function	titin binding
D	0031941	cellular_component	filamentous actin
D	0032036	molecular_function	myosin heavy chain binding
D	0032432	cellular_component	actin filament bundle
D	0042802	molecular_function	identical protein binding
D	0044297	cellular_component	cell body
D	0048306	molecular_function	calcium-dependent protein binding
D	0048741	biological_process	skeletal muscle fiber development
D	0051017	biological_process	actin filament bundle assembly
D	0090131	biological_process	mesenchyme migration
D	0098723	cellular_component	skeletal muscle myofibril
D	0140660	molecular_function	cytoskeletal motor activator activity
E	0000287	molecular_function	magnesium ion binding
E	0001725	cellular_component	stress fiber
E	0003785	molecular_function	actin monomer binding
E	0005509	molecular_function	calcium ion binding
E	0005515	molecular_function	protein binding
E	0005523	molecular_function	tropomyosin binding
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0005856	cellular_component	cytoskeleton
E	0005865	cellular_component	striated muscle thin filament
E	0005884	cellular_component	actin filament
E	0010628	biological_process	positive regulation of gene expression
E	0016787	molecular_function	hydrolase activity
E	0019904	molecular_function	protein domain specific binding
E	0030027	cellular_component	lamellipodium
E	0030041	biological_process	actin filament polymerization
E	0030175	cellular_component	filopodium
E	0030240	biological_process	skeletal muscle thin filament assembly
E	0031013	molecular_function	troponin I binding
E	0031432	molecular_function	titin binding
E	0031941	cellular_component	filamentous actin
E	0032036	molecular_function	myosin heavy chain binding
E	0032432	cellular_component	actin filament bundle
E	0042802	molecular_function	identical protein binding
E	0044297	cellular_component	cell body
E	0048306	molecular_function	calcium-dependent protein binding
E	0048741	biological_process	skeletal muscle fiber development
E	0051017	biological_process	actin filament bundle assembly
E	0090131	biological_process	mesenchyme migration
E	0098723	cellular_component	skeletal muscle myofibril
E	0140660	molecular_function	cytoskeletal motor activator activity
F	0000287	molecular_function	magnesium ion binding
F	0001725	cellular_component	stress fiber
F	0003785	molecular_function	actin monomer binding
F	0005509	molecular_function	calcium ion binding
F	0005515	molecular_function	protein binding
F	0005523	molecular_function	tropomyosin binding
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0005856	cellular_component	cytoskeleton
F	0005865	cellular_component	striated muscle thin filament
F	0005884	cellular_component	actin filament
F	0010628	biological_process	positive regulation of gene expression
F	0016787	molecular_function	hydrolase activity
F	0019904	molecular_function	protein domain specific binding
F	0030027	cellular_component	lamellipodium
F	0030041	biological_process	actin filament polymerization
F	0030175	cellular_component	filopodium
F	0030240	biological_process	skeletal muscle thin filament assembly
F	0031013	molecular_function	troponin I binding
F	0031432	molecular_function	titin binding
F	0031941	cellular_component	filamentous actin
F	0032036	molecular_function	myosin heavy chain binding
F	0032432	cellular_component	actin filament bundle
F	0042802	molecular_function	identical protein binding
F	0044297	cellular_component	cell body
F	0048306	molecular_function	calcium-dependent protein binding
F	0048741	biological_process	skeletal muscle fiber development
F	0051017	biological_process	actin filament bundle assembly
F	0090131	biological_process	mesenchyme migration
F	0098723	cellular_component	skeletal muscle myofibril
F	0140660	molecular_function	cytoskeletal motor activator activity
G	0000287	molecular_function	magnesium ion binding
G	0001725	cellular_component	stress fiber
G	0003785	molecular_function	actin monomer binding
G	0005509	molecular_function	calcium ion binding
G	0005515	molecular_function	protein binding
G	0005523	molecular_function	tropomyosin binding
G	0005524	molecular_function	ATP binding
G	0005737	cellular_component	cytoplasm
G	0005856	cellular_component	cytoskeleton
G	0005865	cellular_component	striated muscle thin filament
G	0005884	cellular_component	actin filament
G	0010628	biological_process	positive regulation of gene expression
G	0016787	molecular_function	hydrolase activity
G	0019904	molecular_function	protein domain specific binding
G	0030027	cellular_component	lamellipodium
G	0030041	biological_process	actin filament polymerization
G	0030175	cellular_component	filopodium
G	0030240	biological_process	skeletal muscle thin filament assembly
G	0031013	molecular_function	troponin I binding
G	0031432	molecular_function	titin binding
G	0031941	cellular_component	filamentous actin
G	0032036	molecular_function	myosin heavy chain binding
G	0032432	cellular_component	actin filament bundle
G	0042802	molecular_function	identical protein binding
G	0044297	cellular_component	cell body
G	0048306	molecular_function	calcium-dependent protein binding
G	0048741	biological_process	skeletal muscle fiber development
G	0051017	biological_process	actin filament bundle assembly
G	0090131	biological_process	mesenchyme migration
G	0098723	cellular_component	skeletal muscle myofibril
G	0140660	molecular_function	cytoskeletal motor activator activity
H	0000287	molecular_function	magnesium ion binding
H	0001725	cellular_component	stress fiber
H	0003785	molecular_function	actin monomer binding
H	0005509	molecular_function	calcium ion binding
H	0005515	molecular_function	protein binding
H	0005523	molecular_function	tropomyosin binding
H	0005524	molecular_function	ATP binding
H	0005737	cellular_component	cytoplasm
H	0005856	cellular_component	cytoskeleton
H	0005865	cellular_component	striated muscle thin filament
H	0005884	cellular_component	actin filament
H	0010628	biological_process	positive regulation of gene expression
H	0016787	molecular_function	hydrolase activity
H	0019904	molecular_function	protein domain specific binding
H	0030027	cellular_component	lamellipodium
H	0030041	biological_process	actin filament polymerization
H	0030175	cellular_component	filopodium
H	0030240	biological_process	skeletal muscle thin filament assembly
H	0031013	molecular_function	troponin I binding
H	0031432	molecular_function	titin binding
H	0031941	cellular_component	filamentous actin
H	0032036	molecular_function	myosin heavy chain binding
H	0032432	cellular_component	actin filament bundle
H	0042802	molecular_function	identical protein binding
H	0044297	cellular_component	cell body
H	0048306	molecular_function	calcium-dependent protein binding
H	0048741	biological_process	skeletal muscle fiber development
H	0051017	biological_process	actin filament bundle assembly
H	0090131	biological_process	mesenchyme migration
H	0098723	cellular_component	skeletal muscle myofibril
H	0140660	molecular_function	cytoskeletal motor activator activity
I	0000287	molecular_function	magnesium ion binding
I	0001725	cellular_component	stress fiber
I	0003785	molecular_function	actin monomer binding
I	0005509	molecular_function	calcium ion binding
I	0005515	molecular_function	protein binding
I	0005523	molecular_function	tropomyosin binding
I	0005524	molecular_function	ATP binding
I	0005737	cellular_component	cytoplasm
I	0005856	cellular_component	cytoskeleton
I	0005865	cellular_component	striated muscle thin filament
I	0005884	cellular_component	actin filament
I	0010628	biological_process	positive regulation of gene expression
I	0016787	molecular_function	hydrolase activity
I	0019904	molecular_function	protein domain specific binding
I	0030027	cellular_component	lamellipodium
I	0030041	biological_process	actin filament polymerization
I	0030175	cellular_component	filopodium
I	0030240	biological_process	skeletal muscle thin filament assembly
I	0031013	molecular_function	troponin I binding
I	0031432	molecular_function	titin binding
I	0031941	cellular_component	filamentous actin
I	0032036	molecular_function	myosin heavy chain binding
I	0032432	cellular_component	actin filament bundle
I	0042802	molecular_function	identical protein binding
I	0044297	cellular_component	cell body
I	0048306	molecular_function	calcium-dependent protein binding
I	0048741	biological_process	skeletal muscle fiber development
I	0051017	biological_process	actin filament bundle assembly
I	0090131	biological_process	mesenchyme migration
I	0098723	cellular_component	skeletal muscle myofibril
I	0140660	molecular_function	cytoskeletal motor activator activity
J	0000287	molecular_function	magnesium ion binding
J	0001725	cellular_component	stress fiber
J	0003785	molecular_function	actin monomer binding
J	0005509	molecular_function	calcium ion binding
J	0005515	molecular_function	protein binding
J	0005523	molecular_function	tropomyosin binding
J	0005524	molecular_function	ATP binding
J	0005737	cellular_component	cytoplasm
J	0005856	cellular_component	cytoskeleton
J	0005865	cellular_component	striated muscle thin filament
J	0005884	cellular_component	actin filament
J	0010628	biological_process	positive regulation of gene expression
J	0016787	molecular_function	hydrolase activity
J	0019904	molecular_function	protein domain specific binding
J	0030027	cellular_component	lamellipodium
J	0030041	biological_process	actin filament polymerization
J	0030175	cellular_component	filopodium
J	0030240	biological_process	skeletal muscle thin filament assembly
J	0031013	molecular_function	troponin I binding
J	0031432	molecular_function	titin binding
J	0031941	cellular_component	filamentous actin
J	0032036	molecular_function	myosin heavy chain binding
J	0032432	cellular_component	actin filament bundle
J	0042802	molecular_function	identical protein binding
J	0044297	cellular_component	cell body
J	0048306	molecular_function	calcium-dependent protein binding
J	0048741	biological_process	skeletal muscle fiber development
J	0051017	biological_process	actin filament bundle assembly
J	0090131	biological_process	mesenchyme migration
J	0098723	cellular_component	skeletal muscle myofibril
J	0140660	molecular_function	cytoskeletal motor activator activity
K	0000287	molecular_function	magnesium ion binding
K	0001725	cellular_component	stress fiber
K	0003785	molecular_function	actin monomer binding
K	0005509	molecular_function	calcium ion binding
K	0005515	molecular_function	protein binding
K	0005523	molecular_function	tropomyosin binding
K	0005524	molecular_function	ATP binding
K	0005737	cellular_component	cytoplasm
K	0005856	cellular_component	cytoskeleton
K	0005865	cellular_component	striated muscle thin filament
K	0005884	cellular_component	actin filament
K	0010628	biological_process	positive regulation of gene expression
K	0016787	molecular_function	hydrolase activity
K	0019904	molecular_function	protein domain specific binding
K	0030027	cellular_component	lamellipodium
K	0030041	biological_process	actin filament polymerization
K	0030175	cellular_component	filopodium
K	0030240	biological_process	skeletal muscle thin filament assembly
K	0031013	molecular_function	troponin I binding
K	0031432	molecular_function	titin binding
K	0031941	cellular_component	filamentous actin
K	0032036	molecular_function	myosin heavy chain binding
K	0032432	cellular_component	actin filament bundle
K	0042802	molecular_function	identical protein binding
K	0044297	cellular_component	cell body
K	0048306	molecular_function	calcium-dependent protein binding
K	0048741	biological_process	skeletal muscle fiber development
K	0051017	biological_process	actin filament bundle assembly
K	0090131	biological_process	mesenchyme migration
K	0098723	cellular_component	skeletal muscle myofibril
K	0140660	molecular_function	cytoskeletal motor activator activity
L	0000287	molecular_function	magnesium ion binding
L	0001725	cellular_component	stress fiber
L	0003785	molecular_function	actin monomer binding
L	0005509	molecular_function	calcium ion binding
L	0005515	molecular_function	protein binding
L	0005523	molecular_function	tropomyosin binding
L	0005524	molecular_function	ATP binding
L	0005737	cellular_component	cytoplasm
L	0005856	cellular_component	cytoskeleton
L	0005865	cellular_component	striated muscle thin filament
L	0005884	cellular_component	actin filament
L	0010628	biological_process	positive regulation of gene expression
L	0016787	molecular_function	hydrolase activity
L	0019904	molecular_function	protein domain specific binding
L	0030027	cellular_component	lamellipodium
L	0030041	biological_process	actin filament polymerization
L	0030175	cellular_component	filopodium
L	0030240	biological_process	skeletal muscle thin filament assembly
L	0031013	molecular_function	troponin I binding
L	0031432	molecular_function	titin binding
L	0031941	cellular_component	filamentous actin
L	0032036	molecular_function	myosin heavy chain binding
L	0032432	cellular_component	actin filament bundle
L	0042802	molecular_function	identical protein binding
L	0044297	cellular_component	cell body
L	0048306	molecular_function	calcium-dependent protein binding
L	0048741	biological_process	skeletal muscle fiber development
L	0051017	biological_process	actin filament bundle assembly
L	0090131	biological_process	mesenchyme migration
L	0098723	cellular_component	skeletal muscle myofibril
L	0140660	molecular_function	cytoskeletal motor activator activity
M	0000287	molecular_function	magnesium ion binding
M	0001725	cellular_component	stress fiber
M	0003785	molecular_function	actin monomer binding
M	0005509	molecular_function	calcium ion binding
M	0005515	molecular_function	protein binding
M	0005523	molecular_function	tropomyosin binding
M	0005524	molecular_function	ATP binding
M	0005737	cellular_component	cytoplasm
M	0005856	cellular_component	cytoskeleton
M	0005865	cellular_component	striated muscle thin filament
M	0005884	cellular_component	actin filament
M	0010628	biological_process	positive regulation of gene expression
M	0016787	molecular_function	hydrolase activity
M	0019904	molecular_function	protein domain specific binding
M	0030027	cellular_component	lamellipodium
M	0030041	biological_process	actin filament polymerization
M	0030175	cellular_component	filopodium
M	0030240	biological_process	skeletal muscle thin filament assembly
M	0031013	molecular_function	troponin I binding
M	0031432	molecular_function	titin binding
M	0031941	cellular_component	filamentous actin
M	0032036	molecular_function	myosin heavy chain binding
M	0032432	cellular_component	actin filament bundle
M	0042802	molecular_function	identical protein binding
M	0044297	cellular_component	cell body
M	0048306	molecular_function	calcium-dependent protein binding
M	0048741	biological_process	skeletal muscle fiber development
M	0051017	biological_process	actin filament bundle assembly
M	0090131	biological_process	mesenchyme migration
M	0098723	cellular_component	skeletal muscle myofibril
M	0140660	molecular_function	cytoskeletal motor activator activity
N	0000287	molecular_function	magnesium ion binding
N	0001725	cellular_component	stress fiber
N	0003785	molecular_function	actin monomer binding
N	0005509	molecular_function	calcium ion binding
N	0005515	molecular_function	protein binding
N	0005523	molecular_function	tropomyosin binding
N	0005524	molecular_function	ATP binding
N	0005737	cellular_component	cytoplasm
N	0005856	cellular_component	cytoskeleton
N	0005865	cellular_component	striated muscle thin filament
N	0005884	cellular_component	actin filament
N	0010628	biological_process	positive regulation of gene expression
N	0016787	molecular_function	hydrolase activity
N	0019904	molecular_function	protein domain specific binding
N	0030027	cellular_component	lamellipodium
N	0030041	biological_process	actin filament polymerization
N	0030175	cellular_component	filopodium
N	0030240	biological_process	skeletal muscle thin filament assembly
N	0031013	molecular_function	troponin I binding
N	0031432	molecular_function	titin binding
N	0031941	cellular_component	filamentous actin
N	0032036	molecular_function	myosin heavy chain binding
N	0032432	cellular_component	actin filament bundle
N	0042802	molecular_function	identical protein binding
N	0044297	cellular_component	cell body
N	0048306	molecular_function	calcium-dependent protein binding
N	0048741	biological_process	skeletal muscle fiber development
N	0051017	biological_process	actin filament bundle assembly
N	0090131	biological_process	mesenchyme migration
N	0098723	cellular_component	skeletal muscle myofibril
N	0140660	molecular_function	cytoskeletal motor activator activity
O	0000287	molecular_function	magnesium ion binding
O	0001725	cellular_component	stress fiber
O	0003785	molecular_function	actin monomer binding
O	0005509	molecular_function	calcium ion binding
O	0005515	molecular_function	protein binding
O	0005523	molecular_function	tropomyosin binding
O	0005524	molecular_function	ATP binding
O	0005737	cellular_component	cytoplasm
O	0005856	cellular_component	cytoskeleton
O	0005865	cellular_component	striated muscle thin filament
O	0005884	cellular_component	actin filament
O	0010628	biological_process	positive regulation of gene expression
O	0016787	molecular_function	hydrolase activity
O	0019904	molecular_function	protein domain specific binding
O	0030027	cellular_component	lamellipodium
O	0030041	biological_process	actin filament polymerization
O	0030175	cellular_component	filopodium
O	0030240	biological_process	skeletal muscle thin filament assembly
O	0031013	molecular_function	troponin I binding
O	0031432	molecular_function	titin binding
O	0031941	cellular_component	filamentous actin
O	0032036	molecular_function	myosin heavy chain binding
O	0032432	cellular_component	actin filament bundle
O	0042802	molecular_function	identical protein binding
O	0044297	cellular_component	cell body
O	0048306	molecular_function	calcium-dependent protein binding
O	0048741	biological_process	skeletal muscle fiber development
O	0051017	biological_process	actin filament bundle assembly
O	0090131	biological_process	mesenchyme migration
O	0098723	cellular_component	skeletal muscle myofibril
O	0140660	molecular_function	cytoskeletal motor activator activity
P	0000287	molecular_function	magnesium ion binding
P	0001725	cellular_component	stress fiber
P	0003785	molecular_function	actin monomer binding
P	0005509	molecular_function	calcium ion binding
P	0005515	molecular_function	protein binding
P	0005523	molecular_function	tropomyosin binding
P	0005524	molecular_function	ATP binding
P	0005737	cellular_component	cytoplasm
P	0005856	cellular_component	cytoskeleton
P	0005865	cellular_component	striated muscle thin filament
P	0005884	cellular_component	actin filament
P	0010628	biological_process	positive regulation of gene expression
P	0016787	molecular_function	hydrolase activity
P	0019904	molecular_function	protein domain specific binding
P	0030027	cellular_component	lamellipodium
P	0030041	biological_process	actin filament polymerization
P	0030175	cellular_component	filopodium
P	0030240	biological_process	skeletal muscle thin filament assembly
P	0031013	molecular_function	troponin I binding
P	0031432	molecular_function	titin binding
P	0031941	cellular_component	filamentous actin
P	0032036	molecular_function	myosin heavy chain binding
P	0032432	cellular_component	actin filament bundle
P	0042802	molecular_function	identical protein binding
P	0044297	cellular_component	cell body
P	0048306	molecular_function	calcium-dependent protein binding
P	0048741	biological_process	skeletal muscle fiber development
P	0051017	biological_process	actin filament bundle assembly
P	0090131	biological_process	mesenchyme migration
P	0098723	cellular_component	skeletal muscle myofibril
P	0140660	molecular_function	cytoskeletal motor activator activity
Q	0000287	molecular_function	magnesium ion binding
Q	0001725	cellular_component	stress fiber
Q	0003785	molecular_function	actin monomer binding
Q	0005509	molecular_function	calcium ion binding
Q	0005515	molecular_function	protein binding
Q	0005523	molecular_function	tropomyosin binding
Q	0005524	molecular_function	ATP binding
Q	0005737	cellular_component	cytoplasm
Q	0005856	cellular_component	cytoskeleton
Q	0005865	cellular_component	striated muscle thin filament
Q	0005884	cellular_component	actin filament
Q	0010628	biological_process	positive regulation of gene expression
Q	0016787	molecular_function	hydrolase activity
Q	0019904	molecular_function	protein domain specific binding
Q	0030027	cellular_component	lamellipodium
Q	0030041	biological_process	actin filament polymerization
Q	0030175	cellular_component	filopodium
Q	0030240	biological_process	skeletal muscle thin filament assembly
Q	0031013	molecular_function	troponin I binding
Q	0031432	molecular_function	titin binding
Q	0031941	cellular_component	filamentous actin
Q	0032036	molecular_function	myosin heavy chain binding
Q	0032432	cellular_component	actin filament bundle
Q	0042802	molecular_function	identical protein binding
Q	0044297	cellular_component	cell body
Q	0048306	molecular_function	calcium-dependent protein binding
Q	0048741	biological_process	skeletal muscle fiber development
Q	0051017	biological_process	actin filament bundle assembly
Q	0090131	biological_process	mesenchyme migration
Q	0098723	cellular_component	skeletal muscle myofibril
Q	0140660	molecular_function	cytoskeletal motor activator activity
R	0000287	molecular_function	magnesium ion binding
R	0001725	cellular_component	stress fiber
R	0003785	molecular_function	actin monomer binding
R	0005509	molecular_function	calcium ion binding
R	0005515	molecular_function	protein binding
R	0005523	molecular_function	tropomyosin binding
R	0005524	molecular_function	ATP binding
R	0005737	cellular_component	cytoplasm
R	0005856	cellular_component	cytoskeleton
R	0005865	cellular_component	striated muscle thin filament
R	0005884	cellular_component	actin filament
R	0010628	biological_process	positive regulation of gene expression
R	0016787	molecular_function	hydrolase activity
R	0019904	molecular_function	protein domain specific binding
R	0030027	cellular_component	lamellipodium
R	0030041	biological_process	actin filament polymerization
R	0030175	cellular_component	filopodium
R	0030240	biological_process	skeletal muscle thin filament assembly
R	0031013	molecular_function	troponin I binding
R	0031432	molecular_function	titin binding
R	0031941	cellular_component	filamentous actin
R	0032036	molecular_function	myosin heavy chain binding
R	0032432	cellular_component	actin filament bundle
R	0042802	molecular_function	identical protein binding
R	0044297	cellular_component	cell body
R	0048306	molecular_function	calcium-dependent protein binding
R	0048741	biological_process	skeletal muscle fiber development
R	0051017	biological_process	actin filament bundle assembly
R	0090131	biological_process	mesenchyme migration
R	0098723	cellular_component	skeletal muscle myofibril
R	0140660	molecular_function	cytoskeletal motor activator activity
S	0000287	molecular_function	magnesium ion binding
S	0001725	cellular_component	stress fiber
S	0003785	molecular_function	actin monomer binding
S	0005509	molecular_function	calcium ion binding
S	0005515	molecular_function	protein binding
S	0005523	molecular_function	tropomyosin binding
S	0005524	molecular_function	ATP binding
S	0005737	cellular_component	cytoplasm
S	0005856	cellular_component	cytoskeleton
S	0005865	cellular_component	striated muscle thin filament
S	0005884	cellular_component	actin filament
S	0010628	biological_process	positive regulation of gene expression
S	0016787	molecular_function	hydrolase activity
S	0019904	molecular_function	protein domain specific binding
S	0030027	cellular_component	lamellipodium
S	0030041	biological_process	actin filament polymerization
S	0030175	cellular_component	filopodium
S	0030240	biological_process	skeletal muscle thin filament assembly
S	0031013	molecular_function	troponin I binding
S	0031432	molecular_function	titin binding
S	0031941	cellular_component	filamentous actin
S	0032036	molecular_function	myosin heavy chain binding
S	0032432	cellular_component	actin filament bundle
S	0042802	molecular_function	identical protein binding
S	0044297	cellular_component	cell body
S	0048306	molecular_function	calcium-dependent protein binding
S	0048741	biological_process	skeletal muscle fiber development
S	0051017	biological_process	actin filament bundle assembly
S	0090131	biological_process	mesenchyme migration
S	0098723	cellular_component	skeletal muscle myofibril
S	0140660	molecular_function	cytoskeletal motor activator activity
T	0000287	molecular_function	magnesium ion binding
T	0001725	cellular_component	stress fiber
T	0003785	molecular_function	actin monomer binding
T	0005509	molecular_function	calcium ion binding
T	0005515	molecular_function	protein binding
T	0005523	molecular_function	tropomyosin binding
T	0005524	molecular_function	ATP binding
T	0005737	cellular_component	cytoplasm
T	0005856	cellular_component	cytoskeleton
T	0005865	cellular_component	striated muscle thin filament
T	0005884	cellular_component	actin filament
T	0010628	biological_process	positive regulation of gene expression
T	0016787	molecular_function	hydrolase activity
T	0019904	molecular_function	protein domain specific binding
T	0030027	cellular_component	lamellipodium
T	0030041	biological_process	actin filament polymerization
T	0030175	cellular_component	filopodium
T	0030240	biological_process	skeletal muscle thin filament assembly
T	0031013	molecular_function	troponin I binding
T	0031432	molecular_function	titin binding
T	0031941	cellular_component	filamentous actin
T	0032036	molecular_function	myosin heavy chain binding
T	0032432	cellular_component	actin filament bundle
T	0042802	molecular_function	identical protein binding
T	0044297	cellular_component	cell body
T	0048306	molecular_function	calcium-dependent protein binding
T	0048741	biological_process	skeletal muscle fiber development
T	0051017	biological_process	actin filament bundle assembly
T	0090131	biological_process	mesenchyme migration
T	0098723	cellular_component	skeletal muscle myofibril
T	0140660	molecular_function	cytoskeletal motor activator activity
U	0000287	molecular_function	magnesium ion binding
U	0001725	cellular_component	stress fiber
U	0003785	molecular_function	actin monomer binding
U	0005509	molecular_function	calcium ion binding
U	0005515	molecular_function	protein binding
U	0005523	molecular_function	tropomyosin binding
U	0005524	molecular_function	ATP binding
U	0005737	cellular_component	cytoplasm
U	0005856	cellular_component	cytoskeleton
U	0005865	cellular_component	striated muscle thin filament
U	0005884	cellular_component	actin filament
U	0010628	biological_process	positive regulation of gene expression
U	0016787	molecular_function	hydrolase activity
U	0019904	molecular_function	protein domain specific binding
U	0030027	cellular_component	lamellipodium
U	0030041	biological_process	actin filament polymerization
U	0030175	cellular_component	filopodium
U	0030240	biological_process	skeletal muscle thin filament assembly
U	0031013	molecular_function	troponin I binding
U	0031432	molecular_function	titin binding
U	0031941	cellular_component	filamentous actin
U	0032036	molecular_function	myosin heavy chain binding
U	0032432	cellular_component	actin filament bundle
U	0042802	molecular_function	identical protein binding
U	0044297	cellular_component	cell body
U	0048306	molecular_function	calcium-dependent protein binding
U	0048741	biological_process	skeletal muscle fiber development
U	0051017	biological_process	actin filament bundle assembly
U	0090131	biological_process	mesenchyme migration
U	0098723	cellular_component	skeletal muscle myofibril
U	0140660	molecular_function	cytoskeletal motor activator activity
V	0000287	molecular_function	magnesium ion binding
V	0001725	cellular_component	stress fiber
V	0003785	molecular_function	actin monomer binding
V	0005509	molecular_function	calcium ion binding
V	0005515	molecular_function	protein binding
V	0005523	molecular_function	tropomyosin binding
V	0005524	molecular_function	ATP binding
V	0005737	cellular_component	cytoplasm
V	0005856	cellular_component	cytoskeleton
V	0005865	cellular_component	striated muscle thin filament
V	0005884	cellular_component	actin filament
V	0010628	biological_process	positive regulation of gene expression
V	0016787	molecular_function	hydrolase activity
V	0019904	molecular_function	protein domain specific binding
V	0030027	cellular_component	lamellipodium
V	0030041	biological_process	actin filament polymerization
V	0030175	cellular_component	filopodium
V	0030240	biological_process	skeletal muscle thin filament assembly
V	0031013	molecular_function	troponin I binding
V	0031432	molecular_function	titin binding
V	0031941	cellular_component	filamentous actin
V	0032036	molecular_function	myosin heavy chain binding
V	0032432	cellular_component	actin filament bundle
V	0042802	molecular_function	identical protein binding
V	0044297	cellular_component	cell body
V	0048306	molecular_function	calcium-dependent protein binding
V	0048741	biological_process	skeletal muscle fiber development
V	0051017	biological_process	actin filament bundle assembly
V	0090131	biological_process	mesenchyme migration
V	0098723	cellular_component	skeletal muscle myofibril
V	0140660	molecular_function	cytoskeletal motor activator activity
W	0000287	molecular_function	magnesium ion binding
W	0001725	cellular_component	stress fiber
W	0003785	molecular_function	actin monomer binding
W	0005509	molecular_function	calcium ion binding
W	0005515	molecular_function	protein binding
W	0005523	molecular_function	tropomyosin binding
W	0005524	molecular_function	ATP binding
W	0005737	cellular_component	cytoplasm
W	0005856	cellular_component	cytoskeleton
W	0005865	cellular_component	striated muscle thin filament
W	0005884	cellular_component	actin filament
W	0010628	biological_process	positive regulation of gene expression
W	0016787	molecular_function	hydrolase activity
W	0019904	molecular_function	protein domain specific binding
W	0030027	cellular_component	lamellipodium
W	0030041	biological_process	actin filament polymerization
W	0030175	cellular_component	filopodium
W	0030240	biological_process	skeletal muscle thin filament assembly
W	0031013	molecular_function	troponin I binding
W	0031432	molecular_function	titin binding
W	0031941	cellular_component	filamentous actin
W	0032036	molecular_function	myosin heavy chain binding
W	0032432	cellular_component	actin filament bundle
W	0042802	molecular_function	identical protein binding
W	0044297	cellular_component	cell body
W	0048306	molecular_function	calcium-dependent protein binding
W	0048741	biological_process	skeletal muscle fiber development
W	0051017	biological_process	actin filament bundle assembly
W	0090131	biological_process	mesenchyme migration
W	0098723	cellular_component	skeletal muscle myofibril
W	0140660	molecular_function	cytoskeletal motor activator activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	binding site for residue ADP A 401

Chain	Residue
A	GLY156
A	MET305
A	TYR306
A	LYS336
A	ASP157
A	GLY158
A	GLY182
A	LYS213
A	GLU214
A	GLY301
A	GLY302
A	THR303

---

site_id	AC2
Number of Residues	12
Details	binding site for residue ADP B 401

Chain	Residue
B	GLY156
B	ASP157
B	GLY158
B	GLY182
B	LYS213
B	GLU214
B	GLY301
B	GLY302
B	THR303
B	MET305
B	TYR306
B	LYS336

---

site_id	AC3
Number of Residues	12
Details	binding site for residue ADP C 401

Chain	Residue
C	GLY156
C	ASP157
C	GLY158
C	GLY182
C	LYS213
C	GLU214
C	GLY301
C	GLY302
C	THR303
C	MET305
C	TYR306
C	LYS336

---

site_id	AC4
Number of Residues	12
Details	binding site for residue ADP D 401

Chain	Residue
D	GLY156
D	ASP157
D	GLY158
D	GLY182
D	LYS213
D	GLU214
D	GLY301
D	GLY302
D	THR303
D	MET305
D	TYR306
D	LYS336

---

site_id	AC5
Number of Residues	12
Details	binding site for residue ADP E 401

Chain	Residue
E	GLY156
E	ASP157
E	GLY158
E	GLY182
E	LYS213
E	GLU214
E	GLY301
E	GLY302
E	THR303
E	MET305
E	TYR306
E	LYS336

---

site_id	AC6
Number of Residues	12
Details	binding site for residue ADP F 401

Chain	Residue
F	GLY156
F	ASP157
F	GLY158
F	GLY182
F	LYS213
F	GLU214
F	GLY301
F	GLY302
F	THR303
F	MET305
F	TYR306
F	LYS336

---

site_id	AC7
Number of Residues	12
Details	binding site for residue ADP G 401

Chain	Residue
G	GLY156
G	ASP157
G	GLY158
G	GLY182
G	LYS213
G	GLU214
G	GLY301
G	GLY302
G	THR303
G	MET305
G	TYR306
G	LYS336

---

site_id	AC8
Number of Residues	12
Details	binding site for residue ADP H 401

Chain	Residue
H	GLY156
H	ASP157
H	GLY158
H	GLY182
H	LYS213
H	GLU214
H	GLY301
H	GLY302
H	THR303
H	MET305
H	TYR306
H	LYS336

---

site_id	AC9
Number of Residues	12
Details	binding site for residue ADP I 401

Chain	Residue
I	GLY182
I	LYS213
I	GLU214
I	GLY301
I	GLY302
I	THR303
I	MET305
I	TYR306
I	LYS336
I	GLY156
I	ASP157
I	GLY158

---

site_id	AD1
Number of Residues	12
Details	binding site for residue ADP J 401

Chain	Residue
J	GLY156
J	ASP157
J	GLY158
J	GLY182
J	LYS213
J	GLU214
J	GLY301
J	GLY302
J	THR303
J	MET305
J	TYR306
J	LYS336

---

site_id	AD2
Number of Residues	12
Details	binding site for residue ADP K 401

Chain	Residue
K	GLY156
K	ASP157
K	GLY158
K	GLY182
K	LYS213
K	GLU214
K	GLY301
K	GLY302
K	THR303
K	MET305
K	TYR306
K	LYS336

---

site_id	AD3
Number of Residues	12
Details	binding site for residue ADP L 401

Chain	Residue
L	GLY156
L	ASP157
L	GLY158
L	GLY182
L	LYS213
L	GLU214
L	GLY301
L	GLY302
L	THR303
L	MET305
L	TYR306
L	LYS336

---

site_id	AD4
Number of Residues	12
Details	binding site for residue ADP M 401

Chain	Residue
M	GLY156
M	ASP157
M	GLY158
M	GLY182
M	LYS213
M	GLU214
M	GLY301
M	GLY302
M	THR303
M	MET305
M	TYR306
M	LYS336

---

site_id	AD5
Number of Residues	12
Details	binding site for residue ADP N 401

Chain	Residue
N	GLY156
N	ASP157
N	GLY158
N	GLY182
N	LYS213
N	GLU214
N	GLY301
N	GLY302
N	THR303
N	MET305
N	TYR306
N	LYS336

---

site_id	AD6
Number of Residues	12
Details	binding site for residue ADP O 401

Chain	Residue
O	GLY156
O	ASP157
O	GLY158
O	GLY182
O	LYS213
O	GLU214
O	GLY301
O	GLY302
O	THR303
O	MET305
O	TYR306
O	LYS336

---

site_id	AD7
Number of Residues	12
Details	binding site for residue ADP P 401

Chain	Residue
P	GLY156
P	ASP157
P	GLY158
P	GLY182
P	LYS213
P	GLU214
P	GLY301
P	GLY302
P	THR303
P	MET305
P	TYR306
P	LYS336

---

site_id	AD8
Number of Residues	12
Details	binding site for residue ADP Q 401

Chain	Residue
Q	GLY156
Q	ASP157
Q	GLY158
Q	GLY182
Q	LYS213
Q	GLU214
Q	GLY301
Q	GLY302
Q	THR303
Q	MET305
Q	TYR306
Q	LYS336

---

site_id	AD9
Number of Residues	12
Details	binding site for residue ADP R 401

Chain	Residue
R	GLY156
R	ASP157
R	GLY158
R	GLY182
R	LYS213
R	GLU214
R	GLY301
R	GLY302
R	THR303
R	MET305
R	TYR306
R	LYS336

---

site_id	AE1
Number of Residues	12
Details	binding site for residue ADP S 401

Chain	Residue
S	GLY156
S	ASP157
S	GLY158
S	GLY182
S	LYS213
S	GLU214
S	GLY301
S	GLY302
S	THR303
S	MET305
S	TYR306
S	LYS336

---

site_id	AE2
Number of Residues	12
Details	binding site for residue ADP T 401

Chain	Residue
T	GLY156
T	ASP157
T	GLY158
T	GLY182
T	LYS213
T	GLU214
T	GLY301
T	GLY302
T	THR303
T	MET305
T	TYR306
T	LYS336

---

site_id	AE3
Number of Residues	12
Details	binding site for residue ADP U 401

Chain	Residue
U	GLY156
U	ASP157
U	GLY158
U	GLY182
U	LYS213
U	GLU214
U	GLY301
U	GLY302
U	THR303
U	MET305
U	TYR306
U	LYS336

---

site_id	AE4
Number of Residues	12
Details	binding site for residue ADP V 401

Chain	Residue
V	GLY156
V	ASP157
V	GLY158
V	GLY182
V	LYS213
V	GLU214
V	GLY301
V	GLY302
V	THR303
V	MET305
V	TYR306
V	LYS336

---

site_id	AE5
Number of Residues	12
Details	binding site for residue ADP W 401

Chain	Residue
W	GLY156
W	ASP157
W	GLY158
W	GLY182
W	LYS213
W	GLU214
W	GLY301
W	GLY302
W	THR303
W	MET305
W	TYR306
W	LYS336

---

Functional Information from PROSITE/UniProt

site_id	PS00406
Number of Residues	11
Details	ACTINS_1 Actins signature 1. YVGDEAQs.KRG

Chain	Residue	Details
A	TYR53-GLY63

---

site_id	PS00432
Number of Residues	9
Details	ACTINS_2 Actins signature 2. WITKqEYDE

Chain	Residue	Details
A	TRP356-GLU364

---

site_id	PS01132
Number of Residues	13
Details	ACTINS_ACT_LIKE Actins and actin-related proteins signature. LLTEApLNPkaNR

Chain	Residue	Details
A	LEU104-ARG116

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	23
Details	MOD_RES: N-acetylaspartate; in Actin, alpha skeletal muscle => ECO:0000269|PubMed:1150665

Chain	Residue	Details
W	ASP1
A	ASP1
B	ASP1
C	ASP1
D	ASP1
E	ASP1
F	ASP1
G	ASP1
H	ASP1
I	ASP1
J	ASP1
K	ASP1
L	ASP1
M	ASP1
N	ASP1
O	ASP1
P	ASP1
Q	ASP1
R	ASP1
S	ASP1
T	ASP1
U	ASP1
V	ASP1

---

site_id	SWS_FT_FI2
Number of Residues	46
Details	MOD_RES: Methionine (R)-sulfoxide => ECO:0000250|UniProtKB:P68134

Chain	Residue	Details
A	MET44
A	MET47
B	MET44
B	MET47
C	MET44
C	MET47
D	MET44
D	MET47
E	MET44
E	MET47
F	MET44
F	MET47
G	MET44
G	MET47
H	MET44
H	MET47
I	MET44
I	MET47
J	MET44
J	MET47
K	MET44
K	MET47
L	MET44
L	MET47
M	MET44
M	MET47
N	MET44
N	MET47
O	MET44
O	MET47
P	MET44
P	MET47
Q	MET44
Q	MET47
R	MET44
R	MET47
S	MET44
S	MET47
T	MET44
T	MET47
U	MET44
U	MET47
V	MET44
V	MET47
W	MET44
W	MET47

---

site_id	SWS_FT_FI3
Number of Residues	23
Details	MOD_RES: N6-malonyllysine => ECO:0000250

Chain	Residue	Details
A	LYS61
B	LYS61
C	LYS61
D	LYS61
E	LYS61
F	LYS61
G	LYS61
H	LYS61
I	LYS61
J	LYS61
K	LYS61
L	LYS61
M	LYS61
N	LYS61
O	LYS61
P	LYS61
Q	LYS61
R	LYS61
S	LYS61
T	LYS61
U	LYS61
V	LYS61
W	LYS61

---

site_id	SWS_FT_FI4
Number of Residues	23
Details	MOD_RES: Tele-methylhistidine => ECO:0000269|PubMed:1150665, ECO:0000269|PubMed:16905096, ECO:0000269|PubMed:213279, ECO:0000269|PubMed:2395459, ECO:0000269|PubMed:499690, ECO:0007744|PDB:1ATN, ECO:0007744|PDB:1NWK

Chain	Residue	Details
A	HIC73
B	HIC73
C	HIC73
D	HIC73
E	HIC73
F	HIC73
G	HIC73
H	HIC73
I	HIC73
J	HIC73
K	HIC73
L	HIC73
M	HIC73
N	HIC73
O	HIC73
P	HIC73
Q	HIC73
R	HIC73
S	HIC73
T	HIC73
U	HIC73
V	HIC73
W	HIC73

---

site_id	SWS_FT_FI5
Number of Residues	23
Details	MOD_RES: N6-methyllysine => ECO:0000250|UniProtKB:P68133

Chain	Residue	Details
A	LYS84
B	LYS84
C	LYS84
D	LYS84
E	LYS84
F	LYS84
G	LYS84
H	LYS84
I	LYS84
J	LYS84
K	LYS84
L	LYS84
M	LYS84
N	LYS84
O	LYS84
P	LYS84
Q	LYS84
R	LYS84
S	LYS84
T	LYS84
U	LYS84
V	LYS84
W	LYS84

---

site_id	SWS_FT_FI6
Number of Residues	23
Details	MOD_RES: ADP-ribosylarginine; by SpvB => ECO:0000305|PubMed:16905096

Chain	Residue	Details
A	ARG177
B	ARG177
C	ARG177
D	ARG177
E	ARG177
F	ARG177
G	ARG177
H	ARG177
I	ARG177
J	ARG177
K	ARG177
L	ARG177
M	ARG177
N	ARG177
O	ARG177
P	ARG177
Q	ARG177
R	ARG177
S	ARG177
T	ARG177
U	ARG177
V	ARG177
W	ARG177

---