5MSO
Structure of the R domain of carboxylic acid reductase (CAR) from Mycobacterium marinum in complex with NADP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0001676 | biological_process | long-chain fatty acid metabolic process |
| A | 0004467 | molecular_function | long-chain fatty acid-CoA ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0006631 | biological_process | fatty acid metabolic process |
| A | 0016020 | cellular_component | membrane |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| A | 0031177 | molecular_function | phosphopantetheine binding |
| A | 0050661 | molecular_function | NADP binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 28 |
| Details | binding site for residue NAP A 1201 |
| Chain | Residue |
| A | GLY785 |
| A | LYS855 |
| A | PRO880 |
| A | ALA881 |
| A | ALA882 |
| A | THR919 |
| A | SER920 |
| A | TYR956 |
| A | LYS960 |
| A | HOH1329 |
| A | HOH1341 |
| A | THR787 |
| A | HOH1381 |
| A | HOH1395 |
| A | HOH1401 |
| A | HOH1404 |
| A | HOH1409 |
| A | HOH1439 |
| A | HOH1517 |
| A | HOH1569 |
| A | HOH1587 |
| A | GLY788 |
| A | PHE789 |
| A | LEU790 |
| A | GLY791 |
| A | ARG814 |
| A | ARG824 |
| A | ASP854 |
Functional Information from PROSITE/UniProt
| site_id | PS00061 |
| Number of Residues | 29 |
| Details | ADH_SHORT Short-chain dehydrogenases/reductases family signature. SatravddsyAngYSNSKWAGeVLLrEAH |
| Chain | Residue | Details |
| A | SER943-HIS971 |
| site_id | PS00455 |
| Number of Residues | 12 |
| Details | AMP_BINDING Putative AMP-binding domain signature. LIYTSGSTGaPK |
| Chain | Residue | Details |
| A | LEU250-LYS261 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 5 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"28719588","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5MSO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5MSU","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_02247","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"28719588","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5MSO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5MSU","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
