Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004089 | molecular_function | carbonate dehydratase activity |
| A | 0008270 | molecular_function | zinc ion binding |
| B | 0004089 | molecular_function | carbonate dehydratase activity |
| B | 0008270 | molecular_function | zinc ion binding |
| C | 0004089 | molecular_function | carbonate dehydratase activity |
| C | 0008270 | molecular_function | zinc ion binding |
| D | 0004089 | molecular_function | carbonate dehydratase activity |
| D | 0008270 | molecular_function | zinc ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 301 |
| Chain | Residue |
| A | HIS91 |
| A | HIS93 |
| A | HIS117 |
| A | V13303 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 302 |
| Chain | Residue |
| A | GLU147 |
| A | PRO214 |
| A | GLN216 |
| A | HOH416 |
| A | HOH458 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | binding site for residue V13 A 303 |
| Chain | Residue |
| A | GLN89 |
| A | HIS91 |
| A | HIS93 |
| A | HIS117 |
| A | VAL119 |
| A | LEU139 |
| A | VAL141 |
| A | LEU197 |
| A | THR198 |
| A | THR199 |
| A | TRP208 |
| A | ZN301 |
| A | HOH552 |
| A | HOH580 |
| A | HOH625 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 301 |
| Chain | Residue |
| B | HIS91 |
| B | HIS93 |
| B | HIS117 |
| B | V13305 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue PEG B 302 |
| Chain | Residue |
| B | VAL107 |
| B | GLN110 |
| B | HIS111 |
| B | PHE112 |
| B | HOH409 |
| B | HOH529 |
| B | HOH581 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 303 |
| Chain | Residue |
| A | PHE7 |
| A | ASN244 |
| A | HOH572 |
| B | LYS251 |
| B | ASP253 |
| B | HOH406 |
| B | HOH487 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 304 |
| Chain | Residue |
| B | ARG212 |
| B | ASN213 |
| site_id | AC8 |
| Number of Residues | 18 |
| Details | binding site for residue V13 B 305 |
| Chain | Residue |
| B | GLN89 |
| B | HIS91 |
| B | HIS93 |
| B | HIS117 |
| B | VAL119 |
| B | ALA129 |
| B | LEU139 |
| B | VAL141 |
| B | LEU197 |
| B | THR198 |
| B | THR199 |
| B | PRO200 |
| B | PRO201 |
| B | TRP208 |
| B | ZN301 |
| B | HOH407 |
| B | HOH503 |
| B | HOH606 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue ZN C 301 |
| Chain | Residue |
| C | HIS91 |
| C | HIS93 |
| C | HIS117 |
| C | V13302 |
| site_id | AD1 |
| Number of Residues | 14 |
| Details | binding site for residue V13 C 302 |
| Chain | Residue |
| C | GLN89 |
| C | HIS91 |
| C | HIS93 |
| C | HIS117 |
| C | VAL119 |
| C | LEU139 |
| C | VAL141 |
| C | LEU197 |
| C | THR198 |
| C | THR199 |
| C | TRP208 |
| C | ZN301 |
| C | HOH560 |
| C | HOH567 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN D 301 |
| Chain | Residue |
| D | HIS91 |
| D | HIS93 |
| D | HIS117 |
| D | V13305 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO D 302 |
| Chain | Residue |
| D | SER42 |
| D | THR44 |
| D | GLY80 |
| D | TYR190 |
| D | ARG192 |
| D | HOH569 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue EDO D 303 |
| Chain | Residue |
| D | LEU43 |
| D | ARG192 |
| D | HOH569 |
| site_id | AD5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO D 304 |
| Chain | Residue |
| D | HOH527 |
| D | SER133 |
| D | ASN134 |
| D | PRO201 |
| D | ASN203 |
| D | HOH430 |
| D | HOH452 |
| site_id | AD6 |
| Number of Residues | 16 |
| Details | binding site for residue V13 D 305 |
| Chain | Residue |
| D | GLN89 |
| D | HIS91 |
| D | HIS93 |
| D | HIS117 |
| D | VAL119 |
| D | ALA129 |
| D | SER130 |
| D | LEU139 |
| D | VAL141 |
| D | LEU197 |
| D | THR198 |
| D | THR199 |
| D | TRP208 |
| D | ZN301 |
| D | HOH422 |
| D | HOH577 |
Functional Information from PROSITE/UniProt
| site_id | PS00162 |
| Number of Residues | 17 |
| Details | ALPHA_CA_1 Alpha-carbonic anhydrases signature. SEHtVsgqhFaaELHIV |
| Chain | Residue | Details |
| A | SER103-VAL119 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | HIS66 | |
| B | HIS66 | |
| C | HIS66 | |
| D | HIS66 | |
| Chain | Residue | Details |
| A | HIS91 | |
| A | HIS93 | |
| A | HIS117 | |
| B | HIS91 | |
| B | HIS93 | |
| B | HIS117 | |
| C | HIS91 | |
| C | HIS93 | |
| C | HIS117 | |
| D | HIS91 | |
| D | HIS93 | |
| D | HIS117 | |
| Chain | Residue | Details |
| A | THR198 | |
| B | THR198 | |
| C | THR198 | |
| D | THR198 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN52 | |
| A | ASN134 | |
| B | ASN52 | |
| B | ASN134 | |
| C | ASN52 | |
| C | ASN134 | |
| D | ASN52 | |
| D | ASN134 | |
