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5MS3

Kallikrein-related peptidase 8 calcium complex

Functional Information from GO Data
ChainGOidnamespacecontents
A0004252molecular_functionserine-type endopeptidase activity
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0005737cellular_componentcytoplasm
A0006508biological_processproteolysis
A0007613biological_processmemory
A0008233molecular_functionpeptidase activity
A0008236molecular_functionserine-type peptidase activity
A0009611biological_processresponse to wounding
A0030141cellular_componentsecretory granule
A0043616biological_processkeratinocyte proliferation
A0048812biological_processneuron projection morphogenesis
A0050807biological_processregulation of synapse organization
A0050808biological_processsynapse organization
A0097180cellular_componentserine protease inhibitor complex
Functional Information from PDB Data
site_idAC1
Number of Residues6
Detailsbinding site for residue CA A 3001
ChainResidue
AASP70
ASER72
AASN75
AASP77
AGLU80
AHOH3139

Functional Information from PROSITE/UniProt
site_idPS00134
Number of Residues6
DetailsTRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC
ChainResidueDetails
ALEU53-CYS58

site_idPS00135
Number of Residues12
DetailsTRYPSIN_SER Serine proteases, trypsin family, serine active site. DTcqGDSGGPLV
ChainResidueDetails
AASP189-VAL200

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsACT_SITE: Charge relay system => ECO:0000250
ChainResidueDetails
ALYS59
APHE151

site_idSWS_FT_FI2
Number of Residues1
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
AGLY49

220472

PDB entries from 2024-05-29

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